Beta-lactamase 3D structures: Difference between revisions
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
* | *β-lactamase class A | ||
**[[ | **[[1btl]], [[1iys]], [[1xpb]], [[1zg4]], [[4gku]], [[4rva]], [[5npo]], [[7u6q]], [[8gii]] - EcBlac A Tem-1- ''Escherichia coli'' | ||
**[[1bza]], [[1ck3]], [[1esu]], [[1jwp]], [[1lhy]], [[1li0]], [[1m40]], [[1zg6]], [[2v1z]], [[2v20]], [[3cmz]], [[3jyi]], [[3dtm]], [[4ibr]], [[4ibx]], [[4mez]], [[4rx2]], [[4rx3]], [[6b2n]], [[5kpu]], [[5iq8]], [[5i63]], [[5i52]], [[5hw5]], [[5hw1]], [[5hvi]], [[6ayk]], [[6apa]], [[8ddz]], [[8gij]], [[8rqu]] - EcBlac A Tem-1 (mutant) | |||
**[[4r4s]], [[4r4r]], [[4qy6]], [[4qy5]] - EcBlac A Tem-1/PSE-4<br /> | **[[4r4s]], [[4r4r]], [[4qy6]], [[4qy5]] - EcBlac A Tem-1/PSE-4<br /> | ||
**[[1lhy]] - EcBlac A Tem-30 (mutant) | **[[8di7]] - EcBlac A CMY-2<br /> | ||
**[[1li0]] - EcBlac A Tem-32 (mutant) | **[[1lhy]] - EcBlac A Tem-30 (mutant) | ||
**[[1li9]] - EcBlac A Tem-34 (mutant) | **[[1li0]] - EcBlac A Tem-32 (mutant) | ||
**[[1yt4]] - EcBlac A Tem-76 (mutant) | **[[1li9]] - EcBlac A Tem-34 (mutant) | ||
**[[3toi]] - EcBlac A Tem-116 (mutant)<br /> | **[[1yt4]] - EcBlac A Tem-76 (mutant) | ||
**[[3toi]] - EcBlac A Tem-116 (mutant) | |||
**[[7qor]] – EcBlac Tem-171 <br /> | |||
**[[5chu]], [[5cgs]] – EcBlac FOX-4<br /> | **[[5chu]], [[5cgs]] – EcBlac FOX-4<br /> | ||
**[[5cgw]] – EcBlac FOX-4 (mutant)<br /> | **[[5cgw]] – EcBlac FOX-4 (mutant)<br /> | ||
**[[4zj2]], [[4zj1]] – EcBlac Tem (mutant) <br /> | **[[4zj2]], [[4zj1]] – EcBlac Tem (mutant) <br /> | ||
**[[4id4]] – EcBlac/PaBlac Tem<br /> | **[[4id4]] – EcBlac/PaBlac Tem<br /> | ||
**[[ | **[[1o7e]], [[1n4o]], [[5ne2]], [[7uhr]], [[7uhs]], [[7uht]], [[8iso]] – StmBlac A – ''Stenotrophonas maltophilia'' | ||
**[[1htz]] – KpBlac A Tem-52 – ''Klebsiella pneumoniae'' | |||
**[[1htz]] – KpBlac A Tem-52 – ''Klebsiella pneumoniae'' | **[[1shv]], [[4fh4]], [[4fcf]], [[4jpm]] - KpBlac A Shv-1 | ||
**[[1shv]], [[4fh4]], [[4fcf]], [[4jpm]] - KpBlac A Shv-1 | **[[1tdl]], [[2a3u]], [[3oph]], [[3opl]], [[3v50]], [[3v5m]], [[4fd8]] - KpBlac A Shv-1 (mutant) | ||
**[[1tdl]], [[2a3u]], [[3oph]], [[3opl]], [[3v50]], [[3v5m]], [[4fd8]] - KpBlac A Shv-1 (mutant) | **[[1n9b]] – KpBlac A Shv-2 | ||
**[[1n9b]] – KpBlac A Shv-2 | |||
**[[6nfd]] - KpBlac A Shv-11 (mutant) <br /> | **[[6nfd]] - KpBlac A Shv-11 (mutant) <br /> | ||
**[[5haq]], [[5hap]] - KpBlac A (mutant) <br /> | **[[5haq]], [[5hap]] - KpBlac A (mutant) <br /> | ||
**[[1hzo]] – Blac A – ''Proteus vulgaris'' | |||
**[[1kge]], [[1kgf]], [[1kgg]], [[1ome]] – SaBlac A (mutant) - ''Staphylococcus aureus'' | |||
**[[1hzo]] – Blac A – ''Proteus vulgaris'' | **[[3blm]] – SaBlac A | ||
**[[1kge]], [[1kgf]], [[1kgg]], [[1ome]] – SaBlac A (mutant) - | **[[1mbl]], [[3ly3]], [[3soi]], [[4n92]], [[5ghx]], [[5zfl]] – BlBlac A (mutant) – ''Bacillus licheniformis'' | ||
**[[3blm]] – SaBlac A | **[[2blm]], [[3sh7]] – BlBlac A | ||
**[[1mbl]], [[3ly3]], [[3soi]], [[4n92]], [[5ghx]], [[5zfl]] – BlBlac A (mutant) – ''Bacillus licheniformis'' | **[[2cc1]] – Blac A – ''Mycobacterium fortuitum'' | ||
**[[2blm]], [[3sh7 | **[[3bfd]], [[3bfe]] – CsBlac A Sed-1 (mutant) - ''Citrobacter sedlakii'' | ||
**[[2cc1]] – Blac A – ''Mycobacterium fortuitum'' | |||
**[[3bfd]], [[3bfe]] – CsBlac A Sed-1 (mutant) - ''Citrobacter sedlakii'' | |||
**[[3s4x]], [[5har]], [[5hai]] - EncBlac A (mutant) – ''Enterobacter cloacae''<br /> | **[[3s4x]], [[5har]], [[5hai]] - EncBlac A (mutant) – ''Enterobacter cloacae''<br /> | ||
**[[3zdj]], [[4b88]] – Blac – precambrian<br /> | **[[3zdj]], [[4b88]] – Blac – precambrian<br /> | ||
**[[4c6y]], [[4c75]], [[5fqm]] – Blac – synthetic<br /> | **[[4c6y]], [[4c75]], [[5fqm]], [[6tww]], [[6txd]], [[6ty6]], [[6yrs]] – Blac – synthetic<br /> | ||
**[[5tfq]] – Blac – ''Bacterioides cellulosilyticus''<br /> | **[[5tfq]] – Blac – ''Bacterioides cellulosilyticus''<br /> | ||
**[[5glc]], [[5gla]], [[5gl9]] - BtBlac A - ''Burkholderia thailandensis''<br /> | **[[5glc]], [[5gla]], [[5gl9]] - BtBlac A - ''Burkholderia thailandensis''<br /> | ||
**[[6afm]], [[6afo]] - BtBlac A (mutant)<br /> | |||
**[[4yfm]] – Blac – ''Mycobacterium abscessus''<br /> | **[[4yfm]] – Blac – ''Mycobacterium abscessus''<br /> | ||
**[[6ni1]] – BsBlac A – ''Bacillus subtilis''<br /> | **[[6ni1]] – BsBlac A – ''Bacillus subtilis''<br /> | ||
**[[6niq]] – Blac A – ''Rhodopseudomonas palustris''<br /> | **[[6niq]] – Blac A – ''Rhodopseudomonas palustris''<br /> | ||
**[[6nj1]] – Blac A – ''Clostridium kluyveri''<br /> | **[[6nj1]] – Blac A – ''Clostridium kluyveri''<br /> | ||
**[[6b6a]], [[6b6b]], [[6b69]], [[6b68]], [[6b5x]] – MtBlac – ''Mycobacterium tuberculosis''<br /> | **[[6b6a]], [[6b6b]], [[6b69]], [[6b68]], [[6b5x]], [[6n14]], [[8gcs]], [[8gcv]], [[8rg2]] – MtBlac – ''Mycobacterium tuberculosis''<br /> | ||
**[[8oe1]], [[8oe5]], [[8rii]] - MtBlac A (mutant)<br /> | |||
**[[6v6n]] - Blac A (mutant) – ''Agrobacterium tumefaciens'' <br /> | |||
**[[6w34]] – BcBlac A (mutant) - ''Bacillus cereus''<br /> | |||
**[[6wip]] – Blac A – ''Micromonospora aurantiaca''<br /> | |||
**[[6l3s]] – MmBlac Imp-27 – ''Morganella morganii''<br /> | |||
**[[9bzn]] – BbBlac A – ''Bordetella bronchiseptica''<br /> | |||
**[[8j6y]], [[8sdl]] - PaBlac A - ''Pseudomonas aeruginosa'' <br /> | |||
**[[8sdn]] - PaBlac A (mutant)<br /> | |||
**[[8qnn]] – Blac A – ''Nocardia cyriacigeorgica''<br /> | |||
**[[8iwv]] – YeBlac A – ''Yersinia enterocolitica''<br /> | |||
*β-lactamase class A binary complex | *β-lactamase class A binary complex | ||
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**[[5ujo]] - EcBlac A (mutant) + organometallics<br /> | **[[5ujo]] - EcBlac A (mutant) + organometallics<br /> | ||
**[[5fa7]] - EcBlac A + inhibitor<br /> | **[[5fa7]] - EcBlac A + inhibitor<br /> | ||
**[[1nxy]], [[1ny0]], [[1nym]], [[1nyy]] - EcBlac A (mutant) + boronic acid inhibitor<br /> | **[[1nxy]], [[1ny0]], [[1nym]], [[1nyy]], [[8sds]] - EcBlac A (mutant) + boronic acid inhibitor<br /> | ||
**[[8de0]] - EcBlac A Tem-1 + drug<br /> | |||
**[[8de1]], [[8de2]] - EcBlac A Tem-1 (mutant) + drug<br /> | |||
**[[1pzo]], [[1pzp]] - EcBlac A Tem-1 (mutant) + inhibitor<br /> | **[[1pzo]], [[1pzp]] - EcBlac A Tem-1 (mutant) + inhibitor<br /> | ||
**[[1erm]], [[1ero]], [[1erq]] – EcBlac A Tem-1 + boronic acid inhibitor<br /> | **[[1erm]], [[1ero]], [[1erq]] – EcBlac A Tem-1 + boronic acid inhibitor<br /> | ||
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**[[1ong]], [[1q2p]], [[1vm1]], [[2h5s]], [[2zd8]], [[3d4f]], [[3mke]], [[3mkf]], [[3mxr]], [[3mxs]], [[4fh2]], [[4gd6]], [[4gd8]], [[4gdb]], [[4mbf]], [[4r3b]], [[5ee8]], [[4zam]] - KpBlac A Shv-1 + inhibitor<br /> | **[[1ong]], [[1q2p]], [[1vm1]], [[2h5s]], [[2zd8]], [[3d4f]], [[3mke]], [[3mkf]], [[3mxr]], [[3mxs]], [[4fh2]], [[4gd6]], [[4gd8]], [[4gdb]], [[4mbf]], [[4r3b]], [[5ee8]], [[4zam]] - KpBlac A Shv-1 + inhibitor<br /> | ||
**[[1rcj]], [[1tdg]], [[2a49]], [[2h0t]], [[2h0y]], [[2h10]], [[4mbh]], [[4mbk]] - KpBlac A Shv-1 (mutant) + inhibitor<br /> | **[[1rcj]], [[1tdg]], [[2a49]], [[2h0t]], [[2h0y]], [[2h10]], [[4mbh]], [[4mbk]] - KpBlac A Shv-1 (mutant) + inhibitor<br /> | ||
**[[5t66]] - KpBlac A + boronic acid inhibitor<br /> | **[[5t66]], [[5zyb]] - KpBlac A + boronic acid inhibitor<br /> | ||
**[[1w7f]], [[3b3x]], [[2y91]], [[4a5r]] - BlBlac A + inhibitor<br /> | **[[1w7f]], [[3b3x]], [[2y91]], [[4a5r]] - BlBlac A + inhibitor<br /> | ||
**[[3m2j]], [[4n9k]], [[4n9l]] - BlBlac A (mutant) + inhibitor<br /> | **[[3m2j]], [[4n9k]], [[4n9l]] - BlBlac A (mutant) + inhibitor<br /> | ||
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**[[2q9m]], [[2q9n]] - EncBlac A + inhibitor <br /> | **[[2q9m]], [[2q9n]] - EncBlac A + inhibitor <br /> | ||
**[[3bfc]], [[3bff]], [[3bfg]] – CsBlac A Sed-1 (mutant) + inhibitor<br /> | **[[3bfc]], [[3bff]], [[3bfg]] – CsBlac A Sed-1 (mutant) + inhibitor<br /> | ||
**[[3nia]] - PaBlac A Ges-2 + inhibitor<br /> | **[[3nia]] - PaBlac A Ges-2 + inhibitor <br /> | ||
**[[3p98]] – | **[[6q35]], [[8sdv]] - PaBlac A Ges-5 + boronic acid inhibitor <br /> | ||
**[[3p98]] – MmBlac Tem-72 + citrate <br /> | |||
**[[5tg7]], [[5tg6]], [[5tg5]], [[5tg4]] - AbBlac A + boronic acid inhibitor<br /> | **[[5tg7]], [[5tg6]], [[5tg5]], [[5tg4]] - AbBlac A + boronic acid inhibitor<br /> | ||
**[[5gld]], [[5glb]] - BtBlac A + boronic acid inhibitor <br /> | **[[5gld]], [[5glb]] - BtBlac A + boronic acid inhibitor <br /> | ||
**[[6afn]], [[6afp]] - BtBlac A (mutant) + boronic acid inhibitor <br /> | |||
**[[5ne1]] - StmBlac A + boronic acid inhibitor <br /> | **[[5ne1]] - StmBlac A + boronic acid inhibitor <br /> | ||
**[[6qw7]], [[6qw8]], [[7bj8]] - StmBlac A + inhibitor <br /> | |||
**[[6w2z]] - BsBlac A + inhibitor <br /> | |||
**[[6w33]] – BcBlac A (mutant) + inhibitor <br /> | |||
**[[9bzr]] - BbBlac A + drug<br /> | |||
*β-lactamase class A binary complex with antibiotics | *β-lactamase class A binary complex with antibiotics | ||
**[[7qlp]], [[7qnk]] – EcBlac Tem-171 + antibiotic<br /> | |||
**[[1tem]], [[1bt5]], [[1fqg]], [[1iyo]], [[1iyp]], [[1iyq]], [[1jvj]], [[3q07]], [[3q1f]] - EcBlac A (mutant) + antibiotic<br /> | **[[1tem]], [[1bt5]], [[1fqg]], [[1iyo]], [[1iyp]], [[1iyq]], [[1jvj]], [[3q07]], [[3q1f]] - EcBlac A (mutant) + antibiotic<br /> | ||
**[[5kmw]] - EcBlac A (mutant) + penicillin derivative<br /> | **[[5kmw]] - EcBlac A (mutant) + penicillin derivative<br /> | ||
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**[[3ly4]], [[3m2k]], [[3sh8]], [[3sh9]], [[5ghz]], [[5ghy]], [[5zg6]], [[5zft]] – BlBlac A (mutant) + antibiotic<br /> | **[[3ly4]], [[3m2k]], [[3sh8]], [[3sh9]], [[5ghz]], [[5ghy]], [[5zg6]], [[5zft]] – BlBlac A (mutant) + antibiotic<br /> | ||
**[[5l2f]] - AbBlac A + antibiotic<br /> | **[[5l2f]] - AbBlac A + antibiotic<br /> | ||
**[[5ne3]] - StmBlac A + antibiotic <br /> | **[[5ne3]], [[7uhj]], [[7uhk]], [[7uhm]], [[7uhn]], [[7uho]], [[7uhp]], [[7uhq]], [[7zo2]], [[7zo3]], [[7zo4]], [[7zo5]], [[7zo6]], [[7zo7]] - StmBlac A + antibiotic <br /> | ||
**[[6dmh]] - SfBlac A (mutant) + antibiotic - ''Serratia fonticola''<br /> | **[[6dmh]] - SfBlac A (mutant) + antibiotic - ''Serratia fonticola''<br /> | ||
**[[6b6f]], [[6b6e]], [[6b6d]], [[6b6c]], [[6b5y]] – MtBlac + antibiotic<br /> | **[[6b6f]], [[6b6e]], [[6b6d]], [[6b6c]], [[6b5y]], [[8bv4]], [[8ebi]], [[8ebr]], [[8gct]], [[8gcx]] – MtBlac + antibiotic<br /> | ||
**[[8btv]], [[8btw]] – MtBlac A (mutant) + antibiotic<br /> | |||
**[[8v9g]] - KpBlac A + antibiotic<br /> | |||
**[[8ix8]], [[8ixx]], [[8iy4]] – YeBlac A + antibiotic <br /> | |||
**[[9bzq]] - BbBlac A + antibiotic<br /> | |||
**[[8eo6]] - meBlac A + antibiotic<br /> | |||
*Extended-spectrum β-lactamase class A | *Extended-spectrum β-lactamase class A | ||
**[[3ni9]] - PaESBL A | **[[3ni9]] - PaESBL A Ges-2<br /> | ||
**[[4gnu]], [[4h8r]] - PaESBL A | **[[4gnu]], [[4h8r]] - PaESBL A Ges-5<br /> | ||
**[[5f83]], [[5f82]] - PaESBL A | **[[5f83]], [[5f82]] - PaESBL A Ges-5 (mutant)<br /> | ||
**[[3v3s]] – PaESBL | **[[3v3s]] – PaESBL Ges-18<br /> | ||
**[[1e25]] – PaESBL | **[[1e25]] – PaESBL Per-1 (mutant)<br /> | ||
**[[5eoe]], [[5eoo]] – PaESBL Bel-1 <br /> | **[[5eoe]], [[5eoo]], [[8jk3]] – PaESBL Bel-1 <br /> | ||
**[[4wz5]] – PaESBL Oxa-10 <br /> | **[[8joi]] – PaESBL Bel-1 (mutant)<br /> | ||
**[[5mmy]], [[5mnu]] – PaESBL Oxa-10 (mutant)<br /> | **[[4wz5]], [[9ixn]] – PaESBL Oxa-10 <br /> | ||
**[[5mmy]], [[5mnu]], [[9ixp]] – PaESBL Oxa-10 (mutant)<br /> | |||
**[[9ixq]] – PaESBL Oxa-17 <br /> | |||
**[[4yin]] – PaESBL Oxa-145 <br /> | **[[4yin]] – PaESBL Oxa-145 <br /> | ||
**[[4d2o]] - CfESBL | **[[4d2o]], [[6dgu]] - CfESBL Per-2 – ''Citrobacter freundii''<br /> | ||
**[[5kzh]] - AbESBL A - ''Acinetobacter baumannii''<br /> | **[[5kzh]] - AbESBL A - ''Acinetobacter baumannii''<br /> | ||
**[[3v3r]] - AbESBL A GES-11<br /> | **[[3v3r]] - AbESBL A GES-11<br /> | ||
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**[[1ylj]], [[2p74]] – EcESBL Ctx-M-9<br /> | **[[1ylj]], [[2p74]] – EcESBL Ctx-M-9<br /> | ||
**[[3hre]], [[5kmt]], [[5kmu]], [[5kkf]] - EcESBL Ctx-M-9 (mutant)<br /> | **[[3hre]], [[5kmt]], [[5kmu]], [[5kkf]] - EcESBL Ctx-M-9 (mutant)<br /> | ||
**[[4ua6]] – EcESBL Ctx-M-14 <br /> | **[[4ua6]], [[6d7h]] – EcESBL Ctx-M-14 <br /> | ||
**[[1ylt]], [[5vth]], [[5twd]], [[6cyn]], [[6cyk]] - EcBlac A Ctx-M-14 (mutant)<br /> | **[[1ylt]], [[5vth]], [[5twd]], [[6cyn]], [[6cyk]], [[6d7i]], [[6v5e]], [[6v6g]], [[6v6p]], [[7k2x]], [[7uon]], [[8dod]], [[8doe]], [[8don]], [[8dp4]], [[8dpq]], [[8ela]], [[8elb]], [[8sj3]] - EcBlac A Ctx-M-14 (mutant)<br /> | ||
**[[4hbt]] – EcESBL Ctx-M-15<br /> | **[[4hbt]], [[7u57]] – EcESBL Ctx-M-15<br /> | ||
**[[1ylw]] - EcESBL Ctx-M-16<br /> | **[[1ylw]] - EcESBL Ctx-M-16<br /> | ||
**[[1ylp]] - EcESBL Ctx-M-27 (mutant)<br /> | **[[1ylp]] - EcESBL Ctx-M-27 (mutant)<br /> | ||
**[[5zb7]] – EcESBL Ctx-M-64<br /> | **[[5zb7]] – EcESBL Ctx-M-64<br /> | ||
**[[6j25]] - EcESBL Ctx-M-64 (mutant)<br /> | |||
**[[4c3q]], [[5a93]], [[5a92]], [[5a90]] - EcESBL Ctx-M-97 (mutant)<br /> | **[[4c3q]], [[5a93]], [[5a92]], [[5a90]] - EcESBL Ctx-M-97 (mutant)<br /> | ||
**[[6c78]], [[6c79]], [[6c7a]] - EcESBLToho-1 <br /> | **[[6c78]], [[6c79]], [[6c7a]] - EcESBLToho-1 <br /> | ||
**[[1we4]], [[2xr0]], [[2zq7]], [[2zq8]], [[2zq9]], [[2zqa]], [[2zqc]], [[2zqd]], [[4bd0]], [[4bd1]], [[4c3k]] - EcESBLToho-1 (mutant) <br /> | **[[1we4]], [[2xr0]], [[2zq7]], [[2zq8]], [[2zq9]], [[2zqa]], [[2zqc]], [[2zqd]], [[4bd0]], [[4bd1]], [[4c3k]], [[6u58]] - EcESBLToho-1 (mutant) <br /> | ||
**[[2xqz]], [[2wyx]] - EcESBL Toho-1 (mutant) – Neutron<br /> | **[[2xqz]], [[2wyx]] - EcESBL Toho-1 (mutant) – Neutron<br /> | ||
**[[6nvt]] – EcESBL Tla-1 <br /> | |||
**[[6pq9]] – EcESBL Tla-1 (mutant)<br /> | |||
**[[3zny]] - KpBlac A Ctx-M-12A (mutant) <br /> | **[[3zny]] - KpBlac A Ctx-M-12A (mutant) <br /> | ||
**[[4pm8]] - KpBlac A Ctx-M-14 <br /> | **[[4pm8]], [[7q0z]], [[7zpv]], [[8af7]], [[8af8]] - KpBlac A Ctx-M-14 <br /> | ||
**[[4pm6]], [[4pma]] - KpBlac A Ctx-M-14 (mutant) <br /> | **[[4pm6]], [[4pma]] - KpBlac A Ctx-M-14 (mutant) <br /> | ||
**[[2qpn]] – KpESBL A | **[[7bh3]], [[7bh4]], [[7bh5]], [[7bh6]], [[7bh7]] - KpBlac A Ctx-M-15 <br /> | ||
**[[5gs8]] – SmESBL | **[[7qqc]], [[7r3q]], [[7r3r]] - KpBlac A Ctx-M-15 (mutant)<br /> | ||
**[[2qpn]] – KpESBL A Ges-1<br /> | |||
**[[6ts9]] - PaESBL A Ges-5<br /> | |||
**[[5gs8]] – SmESBL Tla-3 <br /> | |||
**[[6bn3]] – SeESBL Ctx-M-151 – ''Salmonela enterica''<br /> | **[[6bn3]] – SeESBL Ctx-M-151 – ''Salmonela enterica''<br /> | ||
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**[[4gog]] - PaESBL A GES-1 + acyl intermediate<br /> | **[[4gog]] - PaESBL A GES-1 + acyl intermediate<br /> | ||
**[[3nia]] - PaESBL A GES-2 + inhibitor<br /> | **[[3nia]] - PaESBL A GES-2 + inhibitor<br /> | ||
**[[ | **[[1yly]], [[1ym1]], [[1yms]], [[3g2y]], [[3g2z]], [[3g30]], [[3g31]], [[3g32]], [[3g34]], [[3g35]], [[4dds]], [[4ddy]], [[4de0]], [[4de1]], [[4de2]], [[4de3]] - EcBlac A Ctx-M-9 + inhibitor<br /> | ||
**[[4len]] - EcESBL Ctx-M-9 (mutant) + inhibitor<br /> | **[[4len]] - EcESBL Ctx-M-9 (mutant) + inhibitor<br /> | ||
**[[4uaa]], [[4ua7]] – EcESBL Ctx-M-14 + inhibitor<br /> | **[[4uaa]], [[4ua7]], [[6md8]], [[6mia]], [[6mz1]], [[6mz2]], [[6ooe]], [[6oof]], [[6ooj]], [[6ook]], [[7s0v]], [[7u70]] – EcESBL Ctx-M-14 + inhibitor<br /> | ||
**[[ | **[[6bt6]], [[6v7h]], [[6v7t]], [[6v83]], [[6v8v]] – EcESBL Ctx-M-14 (mutant) + inhibitor<br /> | ||
**[[5vle]], [[5top]], [[5toy]] - EcESBL Ctx-M-14 (mutant) + ruthenium inhibitor<br /> | **[[1ylz]], [[4ua9]] – EcESBL Ctx-M-14 + boronic acid inhibitor<br /> | ||
**[[ | **[[5vle]], [[5top]], [[5toy]], [[6vnu]] - EcESBL Ctx-M-14 (mutant) + ruthenium inhibitor<br /> | ||
**[[4hbu]] – EcESBL Ctx-M-15 + inhibitor<br /> | **[[6unb]] – EcESBL Ctx-M-14 + antibiotic<br /> | ||
**[[4xuz]] - KpBlac A Ctx-M-15 + boronic acid inhibitor<br /> | **[[7k2w]], [[7k2y]] – EcESBL Ctx-M-14 (mutant) + antibiotic<br /> | ||
**[[4hbu]], [[6sp6]], [[7u48]], [[7u49]] – EcESBL Ctx-M-15 + inhibitor<br /> | |||
**[[8pco]], [[8r7m]] - KpBlac A Ctx-M-14 + boronic acid inhibitor<br /> | |||
**[[7q0y]], [[8b2o]], [[8b2v]], [[8b2w]], [[8b3m]] – KpESBL Ctx-M-14 + antibiotic<br /> | |||
**[[4xuz]], [[7ti0]], [[8r2y]], [[8r2z]], [[8r30]], [[8r31]] - KpBlac A Ctx-M-15 + boronic acid inhibitor<br /> | |||
**[[7u4b]] – EcESBL Ctx-M-15 + antibiotic<br /> | |||
**[[6bu3]] – EcESBL Ctx-M-27 + inhibitor<br /> | **[[6bu3]] – EcESBL Ctx-M-27 + inhibitor<br /> | ||
**[[4x69]] – EcESBL Ctx-M-44 + inhibitor<br /> | **[[4x69]] – EcESBL Ctx-M-44 + inhibitor<br /> | ||
**[[6ity]], [[6j2o]] – EcESBL Ctx-M-64 + inhibitor<br /> | |||
**[[6j2b]], [[6j2k]] – EcESBL Ctx-M-64 (mutant) + inhibitor<br /> | |||
**[[5g18]] - EcESBL Ctx-M-97 + substrate<br /> | **[[5g18]] - EcESBL Ctx-M-97 + substrate<br /> | ||
**[[4oqh]] - EcESBL Tem-63 (mutant) + boronic acid inhibitor<br /> | **[[4oqh]] - EcESBL Tem-63 (mutant) + boronic acid inhibitor<br /> | ||
**[[4oq0]], [[4opz]] - EcESBL Tem-94 (mutant) + boronic acid inhibitor<br /> | **[[4oq0]], [[4opz]] - EcESBL Tem-94 (mutant) + boronic acid inhibitor<br /> | ||
**[[4c3q]], [[4opz]] - EcESBL Toho-1 (mutant) + boronic acid inhibitor - Neutron<br /> | **[[4c3q]], [[4opz]] - EcESBL Toho-1 (mutant) + boronic acid inhibitor - Neutron<br /> | ||
**[[5x5g]] – SmESBL | **[[6nvu]], [[6pq8]] – EcESBL Tla-1 + inhibitor<br /> | ||
**[[5x5g]] – SmESBL Tla-3 + inhibitor<br /> | |||
**[[6bpf]] – SeESBL Ctx-M-151 + inhibitor <br /> | **[[6bpf]] – SeESBL Ctx-M-151 + inhibitor <br /> | ||
**[[6d3g]] – CfESBL Per-2 + inhibitor <br /> | |||
**[[7bds]] – KpESBL Ctx-M-15 + drug <br /> | |||
**[[7bdr]], [[7qq5]] – KpESBL Ctx-M-15 (mutant) + drug <br /> | |||
*Extended-spectrum β-lactamase class A binary complex with antibiotics | *Extended-spectrum β-lactamase class A binary complex with antibiotics | ||
**[[4qu3]] - PaESBL A | **[[4qu3]] - PaESBL A Ges-2 + antibiotic<br /> | ||
**[[5eph]], [[5eua]] – PaESBL Bel-1 + antibiotic<br /> | **[[5eph]], [[5eua]] – PaESBL Bel-1 + antibiotic<br /> | ||
**[[1ymx]] - EcESBL Ctx-M-9 + antibiotic<br /> | **[[1ymx]] - EcESBL Ctx-M-9 + antibiotic<br /> | ||
**[[3hlw]], [[3huo]], [[3hvf]] - EcESBL Ctx-M-9 (mutant) + antibiotic<br /> | **[[3hlw]], [[3huo]], [[3hvf]] - EcESBL Ctx-M-9 (mutant) + antibiotic<br /> | ||
**[[4xxr]], [[5u53]], [[5tw6]], [[5twe]], [[6cyu]], [[6cyq]]. [[6bt6]] - EcESBL Ctx-M-14 (mutant) + antibiotic<br /> | **[[4xxr]], [[5u53]], [[5tw6]], [[5twe]], [[6cyu]], [[6cyq]]. [[6bt6]] - EcESBL Ctx-M-14 (mutant) + antibiotic<br /> | ||
**[[4pm9]] - KpBlac A Ctx-M-14 + antibiotic<br /> | **[[4pm9]], [[7q11]], [[7q14]] - KpBlac A Ctx-M-14 + antibiotic<br /> | ||
**[[4pm5]], [[4pm7]] - KpBlac A Ctx-M-14 (mutant) + antibiotic<br /> | **[[4pm5]], [[4pm7]] - KpBlac A Ctx-M-14 (mutant) + antibiotic<br /> | ||
**[[4s2i]] - KpBlac A Ctx-M-15 + antibiotic<br /> | **[[4s2i]] - KpBlac A Ctx-M-15 + antibiotic<br /> | ||
**[[5gwa]] – SmESBL | **[[8ehh]] - KpBlac A Ctx-M-96 + antibiotic<br /> | ||
**[[5gwa]], [[7o0o]] – SmESBL Tla-3 + antibiotic<br /> | |||
**[[8isp]], [[8isq]], [[8isr]] - StmESBL (mutant) + antibiotic<br /> | |||
* | *beta-lactamase class A complex with β-lactamase inhibitor protein (Blip) | ||
**[[ | **[[1jtg]], [[2b5r]], [[3c7u]], [[3c7v]] – EcBlac A (mutant) + Protein Blip | ||
**[[1jtd]], [[3gmw]] - EcBlac A + Protein Blip | **[[1jtd]], [[3gmw]] - EcBlac A + Protein Blip | ||
**[[1s0w]], [[1xxm]] - EcBlac A + Protein Blip (mutant) | **[[1s0w]], [[1xxm]] - EcBlac A + Protein Blip (mutant) | ||
**[[2g2u]] - KpBlac A Shv-1 + Protein Blip | **[[7s5s]] - EcBlac CTX-M-15 + Protein Blip | ||
**[[2g2w]], [[3n4i]] - KpBlac A Shv-1 (mutant) + Protein Blip | **[[2g2u]] - KpBlac A Shv-1 + Protein Blip | ||
**[[3c4o]], [[3c4p]] - KpBlac A Shv-1 + Protein Blip (mutant) | **[[2g2w]], [[3n4i]] - KpBlac A Shv-1 (mutant) + Protein Blip | ||
**[[3e2k]], [[3e2l]] - KpBlac A Kpc-2 (mutant) + Protein Blip | **[[3c4o]], [[3c4p]] - KpBlac A Shv-1 + Protein Blip (mutant) | ||
**[[3e2k]], [[3e2l]] - KpBlac A Kpc-2 (mutant) + Protein Blip | |||
**[[3qhv]], [[3qhy]] - Blac A + Protein Blip – ''Bacillus anthracis'' | **[[3qhv]], [[3qhy]] - Blac A + Protein Blip – ''Bacillus anthracis'' | ||
* | *beta-lactamase class B (Zn containing) or metallo-beta-lactamase or NDM | ||
**[[ | **[[1bc2]], [[1bmc]], [[1bvt]], [[1mqo]], [[2bc2]], [[3fcz]], [[3i0v]], [[3i11]], [[3i13]], [[3i14]], [[3i15]], [[3bc2]], [[4c09]], [[4nq4]], [[5fqa]], [[6dja]] – BcBlac B | ||
**[[2m5c]] - BcBlac B – NMR<br /> | **[[2m5c]] - BcBlac B – NMR<br /> | ||
** | **[[1dxk]], [[2bfk]], [[2bfl]], [[2bfz]], [[2bg2]], [[2bg6]], [[2bg7]], [[2bg8]], [[2bga]], [[2nxa]], [[2nyp]], [[2nze]], [[2nzf]], [[2uyx]], [[3knr]], [[3kns]] - BcBlac B (mutant) | ||
**[[1a7t]], [[1znb]], [[2bmi]] – BfBlac B – ''Bacterioides fragilis'' | **[[1a7t]], [[1znb]], [[2bmi]] – BfBlac B – ''Bacterioides fragilis'' | ||
**[[2znb]] - BfBlac B | **[[2znb]] - BfBlac B + Cd | ||
**[[3znb]] – BfBlac B | **[[3znb]] – BfBlac B + Zn + Hg | ||
**[[4znb]] - BfBlac B (mutant) | **[[4znb]] - BfBlac B (mutant) | ||
**[[ | **[[5wck]] – FgBlac B - ''Fluoribacter gormanii'' | ||
**[[1l9y]] - FgBlac B (mutant) | **[[1l9y]] - FgBlac B (mutant) | ||
**[[5n5g]] - PaBlac B Vim-1 | **[[5n5g]] - PaBlac B Vim-1<br /> | ||
**[[1ko2]], [[1ko3]], [[4bz3]], [[4nq2]], [[5yd7]] – PaBlac B Vim-2 | **[[1ko2]], [[1ko3]], [[4bz3]], [[4nq2]], [[5yd7]], [[7cjl]], [[8i52]] – PaBlac B Vim-2 | ||
**[[2whg]], [[2wrs]] - PaBlac B Vim-4 | **[[2whg]], [[2wrs]] - PaBlac B Vim-4 | ||
**[[4d1t]] - PaBlac B Vim-7<br /> | **[[2y87]], [[2y8a]], [[2y8b]], [[4d1t]] - PaBlac B Vim-7<br /> | ||
**[[4d1u]], [[4d1v]], [[4d1w]] - PaBlac B Vim-7 (mutant)<br /> | **[[4d1u]], [[4d1v]], [[4d1w]] - PaBlac B Vim-7 (mutant)<br /> | ||
**[[4awy]], [[4awz]], [[4p62]] - PaBlac B Aim-1 | **[[7yrp]] - PaBlac B Vim-28<br /> | ||
**[[4awy]], [[4awz]], [[4p62]] - PaBlac B Aim-1 | |||
**[[2ynt]], [[2ynu]], [[2ynv]], [[2ynw]] - PaBlac B Gim-1<br /> | **[[2ynt]], [[2ynu]], [[2ynv]], [[2ynw]] - PaBlac B Gim-1<br /> | ||
**[[5act]], [[5acs]], [[5acr]], [[5acq]], [[5acp]] - PaBlac B Gim-1 (mutant)<br /> | **[[5act]], [[5acs]], [[5acr]], [[5acq]], [[5acp]] - PaBlac B Gim-1 (mutant)<br /> | ||
**[[4ax0]], [[4ax1]] - PaBlac B Aim-1 (mutant) | **[[4ax0]], [[4ax1]] - PaBlac B Aim-1 (mutant) | ||
**[[ | **[[2x02]], [[7b3r]], [[7b3s]], [[7b3u]] - PaBlac Oxa-10 | ||
**[[2x01]] - PaBlac Oxa-10 (mutant) | **[[2x01]] - PaBlac Oxa-10 (mutant) | ||
**[[ | **[[9ixo]] - PaBlac Oxa-14 | ||
**[[4uam]], [[2fhx]], [[4bp0]], [[5nde]] - PaBlac Imp-1 <br /> | **[[4uam]], [[2fhx]], [[4bp0]], [[5nde]] - PaBlac Imp-1 <br /> | ||
**[[4f6h]], [[4f6z]], [[5ls3]] – PaBlac Imp-1 (mutant)<br /> | **[[4f6h]], [[4f6z]], [[5ls3]] – PaBlac Imp-1 (mutant)<br /> | ||
**[[6r79]], [[6yi4]] - PaBlac Imp-13 <br /> | |||
**[[5b3r]] - PaBlac Imp-18 <br /> | **[[5b3r]] - PaBlac Imp-18 <br /> | ||
**[[5ev6]], [[5y5b]] - SmBlac Imp-1 – ''Serratia marcescens''<br /> | **[[5ev6]], [[5y5b]], [[7dtm]] - SmBlac Imp-1 – ''Serratia marcescens''<br /> | ||
**[[1wuo]], [[1wup]] - SmBlac Imp-1 (mutant) | **[[1wuo]], [[1wup]], [[7dtn]] - SmBlac Imp-1 (mutant) | ||
**[[3vpe]] - SmBlac Smb-1<br /> | **[[3vpe]] - SmBlac Smb-1<br /> | ||
**[[5fdh]] - SmBlac Oxa-405<br /> | **[[5fdh]] - SmBlac Oxa-405<br /> | ||
**[[2dkf]], [[2zo4]], [[2zwr]] – TtBlac B – ''Thermus thermophilus'' | **[[2dkf]], [[2zo4]], [[2zwr]] – TtBlac B – ''Thermus thermophilus'' | ||
**[[2zzi]] – TtBlac B | **[[2zzi]] – TtBlac B + Fe | ||
**[[2fm6]], [[2fu6]], [[2fu7]], [[2h6a]] – StmMlac B | **[[2fm6]], [[2fu6]], [[2fu7]], [[2h6a]] – StmMlac B | ||
**[[2qin]], [[2qjs]] - StmBlac B (mutant) | **[[2qin]], [[2qjs]] - StmBlac B (mutant) | ||
**[[2gmn]], [[3lvz]] – BjBlac B – ''Bradyrhizobium japonicum'' | **[[2gmn]], [[3lvz]] – BjBlac B – ''Bradyrhizobium japonicum'' | ||
**[[2p4z]] – Blac B – ''Thermoanaerobacter tengcongensis'' | **[[2p4z]] – Blac B – ''Thermoanaerobacter tengcongensis'' | ||
**[[3l6n]] – Blac B – ''Chryseobacter indolegenes'' | **[[3l6n]] – Blac B – ''Chryseobacter indolegenes'' | ||
**[[3r2u]] – SaBlac B | **[[3r2u]] – SaBlac B | ||
**[[3rkj]], [[3sbl]], [[3sfp]], [[3spu]], [[3zr9]], [[3pg4]] | **[[3rkj]], [[3sbl]], [[3sfp]], [[3spu]], [[3zr9]], [[3pg4]], [[3srx]], [[4h0d]], [[6c6i]], [[5xp6]], [[5n0i]], [[5k4m]], [[5jqj]], [[5xp9]], [[5zgi]], [[5nbk]], [[6cac]], [[6ex7]], [[6lhe]], [[6twt]] – KpBlac B Ndm-1 + metal ion | ||
**[[5zgf]], [[7ct2]] - KpBlac B Ndm-1 (mutant) + metal ion<br /> | |||
**[[3rkk]], [[4gyq]], [[4gyu]] - KpBlac B Ndm-1 (mutant) | |||
**[[5zgf]] - KpBlac B Ndm-1 (mutant) + | |||
**[[ | |||
**[[6mh0]] - KpBlac B Ndm-3 + Zn<br /> | **[[6mh0]] - KpBlac B Ndm-3 + Zn<br /> | ||
**[[ | **[[5wig]], [[6mgz]], [[8sk2]] - KpBlac B Ndm-4 + Zn<br /> | ||
**[[6mgy]] - KpBlac B Ndm-5 + Zn<br /> | **[[6mgy]] - KpBlac B Ndm-5 + Zn<br /> | ||
**[[6mgx]] - KpBlac B Ndm-6 + Zn<br /> | **[[6mgx]] - KpBlac B Ndm-6 + Zn<br /> | ||
**[[ | **[[6r78]] - KpBlac Imp-13 <br /> | ||
**[[3s0z]], [[6c89]] - EcBlac B Ndm-1 | **[[3s0z]], [[6c89]], [[5zr8]] - EcBlac B Ndm-1 | ||
**[[4tz9]] - EcBlac B Ndm-3<br /> | **[[4tz9]] - EcBlac B Ndm-3<br /> | ||
**[[4tyf]] - EcBlac B Ndm-4<br /> | **[[4tyf]] - EcBlac B Ndm-4<br /> | ||
Line 222: | Line 265: | ||
**[[5wih]] - EcBlac B Ndm-12<br /> | **[[5wih]] - EcBlac B Ndm-12<br /> | ||
**[[6bm9]] – EcBlac B Vim-2<br /> | **[[6bm9]] – EcBlac B Vim-2<br /> | ||
**[[2yz3]] – Blac Vim-2 – ''Pseudomonas putida'' | **[[7xhw]] - EcBlac Imp-1 <br /> | ||
**[[3sd9]] – SfBlac B | **[[7xhx]], [[7wzu]] - EcBlac Imp-6 <br /> | ||
**[[6skp]], [[6skq]], [[6skr]] - EcBlac Oxa-10 <br /> | |||
**[[6ovz]] - EcBlac <br /> | |||
**[[2yz3]] – Blac Vim-2 – ''Pseudomonas putida'' | |||
**[[3sd9]] – SfBlac B | |||
**[[4ubq]] - AbBlac Imp-2 <br /> | **[[4ubq]] - AbBlac Imp-2 <br /> | ||
**[[5mmd]] - AbBlac Tmb-1 <br /> | **[[5mmd]] - AbBlac Tmb-1 <br /> | ||
**[[5a87]] - KpBlac B | **[[5a87]] - KpBlac B <br /> | ||
**[[4uwo]], [[4uwp]], [[4uwr]], [[4uws]] - KpBlac B Vim-26<br /> | **[[4uwo]], [[4uwp]], [[4uwr]], [[4uws]] - KpBlac B Vim-26<br /> | ||
**[[4wd6]] – PsBlac Dim-1 – ''Pseudomonas stutzeri''<br /> | **[[4wd6]] – PsBlac Dim-1 – ''Pseudomonas stutzeri''<br /> | ||
**[[5iqk]] – Blac – uncultured<br /> | **[[5iqk]], [[7byq]], [[7bz1]], [[7bz3]], [[7bz4]], [[7bzi]] – Blac – uncultured<br /> | ||
**[[5ctn]], [[5ctm]] – Blac – ''Bacillus pumilus''<br /> | **[[5ctn]], [[5ctm]] – Blac – ''Bacillus pumilus''<br /> | ||
**[[4ysb]] – Blac + Fe – ''Myxococcus xanthus''<br /> | **[[4ysb]] – Blac + Fe – ''Myxococcus xanthus''<br /> | ||
**[[6cqs]] – Blac + Zn – Sediminispirochaeta smaragdinae<br /> | **[[6cqs]] – Blac + Zn – ''Sediminispirochaeta smaragdinae''<br /> | ||
**[[6dn4]] – CsBlac – ''Cronobacter sakazakii''<br /> | |||
**[[6dq2]], [[6dqh]], [[6dr8]], [[6nc5]] – CsBlac (mutant)<br /> | |||
**[[6mfi]] – Blac Mim-2 – ''Simiduia agarivorans''<br /> | |||
**[[6t5l]] – Blac B1 Myo-1 – ''Myroides odoratimimus''<br /> | |||
**[[6v54]], [[6v5m]], [[6v70]], [[6v71]] – HbBlac (mutant) – ''Hirschia baltica''<br /> | |||
**[[6v72]], [[6v73]] – ElBlac – ''Erythrobacter litoralis''<br /> | |||
**[[6jv4]] - VaBlac Vmb-1 – ''Vibrio alginolyticus''<br /> | |||
* | *beta-lactamase class B binary complex with antibiotic | ||
**[[5n5i]] - PaBlac B Vim-1 + antibiotic<br /> | **[[5n5i]] - PaBlac B Vim-1 + antibiotic<br /> | ||
**[[4s2o]], [[5mox]], [[5moz]] - PaBlac Oxa-10 + antibiotic<br /> | **[[4s2o]], [[5mox]], [[5moz]], [[9ixr]] - PaBlac Oxa-10 + antibiotic<br /> | ||
**[[6r73]], [[6rzr]], [[6rzs]], [[6s0h]] - PaBlac Imp-13 + antibiotic<br /> | |||
**[[5b1u]], [[5b15]], [[5aya]], [[5axo]] - SmBlac Smb-1 + antibiotic<br /> | **[[5b1u]], [[5b15]], [[5aya]], [[5axo]] - SmBlac Smb-1 + antibiotic<br /> | ||
**[[4zej]] - PsBlac Dim-1 + antibiotic<br /> | **[[4zej]] - PsBlac Dim-1 + antibiotic<br /> | ||
2aio – StmBlac B + antibiotic | **[[2aio]], [[7a63]] – StmBlac B + antibiotic | ||
**[[5zge]], [[4ey2]], [[4eyb]], [[4eyf]], [[4efl]], [[4hl1]], [[4hl2]], [[4eyl]], [[4hky]], [[4ram]], [[4raw]], [[4rbs]], [[4rl0]], [[4rl2]], [[5of2]], [[5o2e]], [[5o2f]], [[6jkb]], [[8gpc]], [[8gpe]] – KpBlac B Ndm-1+ antibiotic | |||
**[[4rm5]] – KpBlac B Ndm-1 (mutant) + antibiotic<br /> | **[[4rm5]] – KpBlac B Ndm-1 (mutant) + antibiotic<br /> | ||
**[[5ypi]], [[5ypk]], [[5ypl]], [[5ypm]], [[5ypn]] – EcBlac B Ndm-1 + antibiotic<br /> | **[[5ypi]], [[5ypk]], [[5ypl]], [[5ypm]], [[5ypn]] – EcBlac B Ndm-1 + antibiotic<br /> | ||
**[[6ol8]] – EcBlac B Ndm-12 + antibiotic<br /> | |||
**[[6lf4]] - VaBlac Vmb-1 + antibiotic <br /> | |||
* | *beta-lactamase class B binary complex | ||
**[[1a8t]], [[1hlk]], [[1kr3]] - BfBlac B + inhibitor | **[[1a8t]], [[1hlk]], [[1kr3]] - BfBlac B + inhibitor | ||
**[[ | **[[5w90]] – FgBlac + captopril | ||
**[[1jje]], [[1jjt]], [[3lce]], [[3wxc]], [[4c1f]], [[4c1g]], [[5ndb]] - PaBlac B Imp-1+ inhibitor | **[[1jje]], [[1jjt]], [[3lce]], [[3wxc]], [[4c1f]], [[4c1g]], [[5ndb]], [[7yh9]], [[7yha]], [[8jao]] - PaBlac B Imp-1 + inhibitor | ||
**[[5n5h]] - PaBlac B Vim-1 + inhibitor<br /> | **[[5n5h]], [[7afy]], [[7ayj]], [[7uya]], [[7uyb]], [[7uyc]], [[8p8y]], [[8p8z]], [[8p92]], [[8p93]], [[8p95]], [[8p9p]], [[8p9q]], [[8p9s]], [[8p9t]], [[8pa3]], [[8pa4]], [[8pa5]], [[8pa7]], [[8paa]], [[8pab]], [[8pac]], [[8pad]], [[8pah]], [[8pal]], [[8pam]], [[8pan]], [[8pao]], [[8pb0]], [[8pb2]], [[8pg2]], [[8pg3]], [[8pg4]], [[8pg5]], [[8pg6]], [[8pg7]], [[8pg8]], [[8pg9]], [[8pga]], [[8pgb]], [[8pgc]], [[8pgd]], [[8pge]], [[8pgf]], [[8pgg]], [[8pgh]], [[8pgi]], [[8pgj]], [[8pgk]], [[8pgl]], [[8pgm]], [[8pgn]], [[8pgo]], [[8pgp]], [[8pgq]], [[8pgr]], [[8pgs]], [[8pgt]], [[8pgu]], [[8pgv]], [[8pgw]], [[8pgx]], [[8pgy]], [[8pgz]], [[8ph0]], [[8ph1]], [[8ph2]], [[8ph3]], [[9c5p]] - PaBlac B Vim-1 + inhibitor<br /> | ||
**[[4c1d]], [[4c1e]], [[4pvo]], [[4pvt]], [[4ua4]], [[5lm6]], [[5le1]], [[5lch]], [[5lcf]], [[5lca]], [[5fqc]], [[5acx]], [[5acw]], [[5acv]], [[5acu]], [[5y6d]], [[5nhz]], [[5ni0]], [[5n4s]], [[5n4t]], [[5mxq]], [[5mxr]], [[5k48]], [[6hf5]], [[6ew3]], [[5y6e]], [[5o7n]] - PaBlac B Vim-2 + inhibitor<br /> | **[[4c1d]], [[4c1e]], [[4pvo]], [[4pvt]], [[4ua4]], [[5lm6]], [[5le1]], [[5lch]], [[5lcf]], [[5lca]], [[5fqc]], [[5acx]], [[5acw]], [[5acv]], [[5acu]], [[5y6d]], [[5nhz]], [[5ni0]], [[5n4s]], [[5n4t]], [[5mxq]], [[5mxr]], [[5k48]], [[6hf5]], [[6ew3]], [[5y6e]], [[5o7n]], [[6dd0]], [[6dd1]], [[6j8r]], [[6kxo]], [[6kzn]], [[6sp7]], [[6v1p]], [[6zyn]], [[6zyo]], [[6zyp]], [[7afx]], [[7chv]], [[7du1]]. [[7dub]], [[7due]], [[7duy]], [[7duz]], [[7dv1]], [[7dyy]], [[7dz0]], [[7dz1]], [[7yhb]], [[7yhc]], [[7yhd]], [[8a4m]], [[8hx5]], [[8hxo]], [[8hxp]], [[8hxu]], [[8hxv]], [[8hxw]], [[8hy1]], [[8hy2]], [[8hyb]], [[8hyd]], [[8r5u]] - PaBlac B Vim-2 + inhibitor<br /> | ||
**[[6ibs]], [[6ibv]], [[6jn6]], [[6o5t]], [[6rpn]] - PaBlac B Vim-2 + boronic acid inhibitor<br /> | |||
**[[7a60]], [[8pjm]] - PaBlac B Vim-2 + antibiotic<br /> | |||
**[[5n55]], [[5n58]] - PaBlac B Vim-5 + inhibitor<br /> | **[[5n55]], [[5n58]] - PaBlac B Vim-5 + inhibitor<br /> | ||
**[[5mm9]] - PaBlac B Vim-17 + inhibitor<br /> | **[[5mm9]] - PaBlac B Vim-17 + inhibitor<br /> | ||
**[[5fq9]] - PaBlac Oxa-10 + inhibitor<br /> | **[[5fq9]], [[6rtn]] - PaBlac Oxa-10 + inhibitor<br /> | ||
**[[1m2x]] – Blac B + captopril – ''Elizabethkingia meningoseptica'' | **[[1m2x]] – Blac B + captopril – ''Elizabethkingia meningoseptica'' | ||
**[[1vgn]], [[3vqz]], [[5hh4]], [[5ewa]], [[5ev8]], [[5axr]] - SmBlac Imp-1+ inhibitor<br /> | **[[1vgn]], [[3vqz]], [[5hh4]], [[5ewa]], [[5ev8]], [[5axr]], [[6jed]], [[6jka]], [[6lbl]], [[8z5l]] - SmBlac Imp-1+ inhibitor | ||
**[[2doo]] - SmBlac Imp-1+ fluorescent agent | **[[6k4t]], [[6k4x]] - SmBlac Smb-1+ inhibitor<br /> | ||
**[[2fu8]], [[2fu9]], [[2gfj]], [[2gfk]], [[2hb9]], [[2qdt]], [[5dpx]] - StmBlac B + inhibitor | **[[2doo]] - SmBlac Imp-1+ fluorescent agent | ||
**[[3iof]], [[1x8i]], [[3iog]]– AhBlac B (mutant) + inhibitor | **[[2fu8]], [[2fu9]], [[2gfj]], [[2gfk]], [[2hb9]], [[2qdt]], [[5dpx]], [[5evk]], [[5evd]], [[5evb]], [[5hh6]], [[5hh5]], [[7afz]], [[7uhi]], [[8hxe]], [[8hxi]] - StmBlac B L1 + inhibitor | ||
**[[1x8g]], [[2gkl]], [[2qds]] – AhBlac B + inhibitor | **[[3iof]], [[1x8i]], [[3iog]]– AhBlac B (mutant) + inhibitor | ||
**[[5wcm]] – BjBlac B + inhibitor | **[[1x8g]], [[2gkl]], [[2qds]] – AhBlac B + inhibitor | ||
**[[2m5d]], [[4c1c]], [[4c1h]], [[4nq5]], [[4nq6]], [[5w8w]], [[4tyt]], [[5jmx]], [[6f2n]], [[6ewe]], [[6eum]] | **[[5wcm]] – BjBlac B + inhibitor | ||
**[[2m5d]], [[4c1c]], [[4c1h]], [[4nq5]], [[4nq6]], [[5w8w]], [[4tyt]], [[5jmx]], [[6f2n]], [[6ewe]], [[6eum]] - BcBlac B + inhibitor<br /> | |||
**[[5ew0]] - SfBlac B + inhibitor<br /> | **[[5ew0]] - SfBlac B + inhibitor<br /> | ||
**[[3q6v]] – SfBlac B + glycerol | **[[3q6v]] – SfBlac B + glycerol | ||
**[[4exy]], [[4exs]], [[4eyl]], [[4hky]], [[ | **[[4exy]], [[4exs]], [[4eyl]], [[4hky]], [[4u4l]], [[5a5z]], [[5n0h]], [[5zjc]], [[5zj8]], [[5zj7]], [[5zj2]], [[5zj1]], [[5zio]], [[5zh1]], [[5zgz]], [[5zgy]], [[5zgx]], [[5zgw]], [[5zgv]] [[5zgu]], [[5zgt]], [[5zgr]], [[5zgq]], [[5zgp]], [[6d1a]], [[6d1b]], [[6d1c]], [[6d1d]], [[6d1e]], [[6d1f]], [[6d1g]], [[6d1h]], [[6d1i]], [[6d1j]], [[6d1k]], [[6efj]], [[6mdu]], [[6ny7]], [[6rmf]], [[6v1m]], [[6xbe]], [[6xbf]], [[6zyq]], [[7up1]], [[7up2]], [[7up3]], [[8hy6]], [[8hyc]], [[8i8e]], [[8r5t]] – KpBlac B Ndm-1+ inhibitor | ||
**[[6o3r]] – KpBlac B Ndm-1 (mutant) + inhibitor<br /> | |||
**[[6q2y]], [[6q30]] – KpBlac B Ndm-1 + boronic acid inhibitor<br /> | |||
**[[5nai]] – KpBlac B Vim-5 + inhibitor<br /> | **[[5nai]] – KpBlac B Vim-5 + inhibitor<br /> | ||
**[[ | **[[6kxi]], [[6kzl]], [[7vqj]] – EcBlac B Ndm-1+ inhibitor<br /> | ||
**[[5fqb]] - BcBlac B + inhibitor<br /> | **[[5fqb]] - BcBlac B + inhibitor<br /> | ||
**[[ | **[[6v61]] – HbBlac (mutant) + inhibitor<br /> | ||
**[[8a76]], [[8b1w]], [[8b1z]], [[8b20]] – PaBlac B Ndm-1+ inhibitor<br /> | |||
* | *beta-lactamase class C | ||
**[[5f1g]], [[5ggw]], [[6g9t]] – EcBlac C<br /> | **[[5f1g]], [[5ggw]], [[6g9t]], [[6xg1]] – EcBlac C<br /> | ||
**[[3fkw]], [[3iwi]], [[3iwo]], [[3iwq]], [[3ixd]] – EcBlac C (mutant) | **[[3fkw]], [[3iwi]], [[3iwo]], [[3iwq]], [[3ixd]] – EcBlac C (mutant) | ||
**[[1zkj]], [[5f1f]], [[5k1d]], [[5gsc]] – EaBlac C – ''Enterobacter aerogenes'' | **[[1zkj]], [[5f1f]], [[5k1d]], [[5gsc]] – EaBlac C – ''Enterobacter aerogenes'' | ||
**[[2qz6]] – Blac C – ''Pseudomonas fluorescens''<br /> | **[[2qz6]] – Blac C – ''Pseudomonas fluorescens'' | ||
**[[3w8k]] – KpBlac C<br /> | **[[7mqn]] – Blac C – ''Rhodobacter sphaeroides''<br /> | ||
**[[3w8k]], [[6k8x]], [[6m5p]] – KpBlac C<br /> | |||
**[[6m5h]], [[6m5q]] – KpBlac C (mutant)<br /> | |||
**[[4u0t]] – AbBlac C Adc-7<br /> | **[[4u0t]] – AbBlac C Adc-7<br /> | ||
**[[8fqv]] – AbBlac C Adc-30<br /> | |||
**[[8fqn]] – AbBlac C Adc-33<br /> | |||
**[[4qd4]] – AbBlac C Adc-68<br /> | **[[4qd4]] – AbBlac C Adc-68<br /> | ||
**[[6fm6]] | **[[8fqp]] – AbBlac C Adc-162<br /> | ||
**[[8fqr]] – AbBlac C Adc-212<br /> | |||
**[[8fqt]] – AbBlac C Adc-219<br /> | |||
**[[6fm6]] - Blac C Tru-1 – ''Aeromonas enteropelogenes''<br /> | |||
* | *beta-lactamase class C binary complex | ||
**[[3bm6]], [[3fkv]], [[3o86]], [[3o87]], [[3o88]] – EcBlac C + boronic acid inhibitor | **[[3gqz]], [[3gr2]], [[3grj]], [[3gsg]], [[3gtc]], [[3gv9]], [[3gvb]], [[6xfs]] - EcBlac C + inhibitor | ||
**[[3ixb]], [[3ixg]] - EcBlac C (mutant) + boronic acid inhibitor | **[[3bm6]], [[3fkv]], [[3o86]], [[3o87]], [[3o88]] – EcBlac C + boronic acid inhibitor | ||
**[[ | **[[3ixb]], [[3ixg]] - EcBlac C (mutant) + boronic acid inhibitor | ||
**[[ | **[[6whf]], [[8ttp]] - EcBlac C + antibiotic<br /> | ||
**[[1onh]], [[1q2q]], [[1y54]] - EncBlac C + inhibitor | **[[3ixh]] - EcBlac C (mutant) + antibiotic | ||
**[[1s6r]] - EncBlac C+ boronic acid inhibitor | **[[1onh]], [[1q2q]], [[1y54]] - EncBlac C + inhibitor | ||
**[[1rgz]], [[5xhr]] - EncBlac C + antibiotic | **[[1s6r]] - EncBlac C+ boronic acid inhibitor | ||
**[1rgy]] - CfBlac C + antibiotic | **[[1rgz]], [[5xhr]] - EncBlac C + antibiotic | ||
**[[1zc2]], [[2zc7]] – KpBlac C + inhibitor | **[[1rgy]] - CfBlac C + antibiotic | ||
**[[1zc2]], [[2zc7]], [[6k9t]], [[6ka5]] – KpBlac C + inhibitor | |||
**[[4wbg]] - KpBlac C + antibiotic<br /> | **[[4wbg]] - KpBlac C + antibiotic<br /> | ||
**[[2wzx]], [[2wzz]], [[6i30]] – PaBlac C + inhibitor | **[[6kby]] - KpBlac C + AMP<br /> | ||
**[[2wzx]], [[2wzz]], [[6i30]] – PaBlac C + inhibitor | |||
**[[4ooy]] - PaBlac C + antibiotic<br /> | **[[4ooy]] - PaBlac C + antibiotic<br /> | ||
**[[4u0x]], [[5wac]], [[5wad]], [[5wae]], [[5waf]], [[5wag]], [[5w12]], [[5w13]], [[5w14]] - AbBlac C Adc-7 + boronic acid inhibitor <br /> | **[[4u0x]], [[5wac]], [[5wad]], [[5wae]], [[5waf]], [[5wag]], [[5w12]], [[5w13]], [[5w14]], [[6tzf]], [[6tzg]], [[6tzi]], [[6tzj]], [[6wif]], [[8fqm]] - AbBlac C Adc-7 + boronic acid inhibitor <br /> | ||
**[[6fm7]] - | **[[8fqw]] - AbBlac C Adc-30 + boronic acid inhibitor <br /> | ||
**[[8fqo]] - AbBlac C Adc-33 + boronic acid inhibitor <br /> | |||
**[[6pwm]] - AbBlac C + antibiotic<br /> | |||
**[[6fm7]] - Blac C Tru-1 + inhibitor <br /> | |||
**[[5k1f]] - EaBlac C + inhibitor <br /> | **[[5k1f]] - EaBlac C + inhibitor <br /> | ||
* | *beta-lactamase class D | ||
** | **[[1k55]], [[1k57]], [[1k4e]], [[1ewz]], [[1fof]], [[1ddk]], [[1e3u]], [[1e4d]], [[1h8z]], [[2rl3]] – PaBlac D | ||
**[[2hp5]], [[2hp6]], [[2hp9]], [[2hpb]], [[2wgw]], [[2wki]] - PaBlac D (mutant) | **[[2hp5]], [[2hp6]], [[2hp9]], [[2hpb]], [[2wgw]], [[2wki]] - PaBlac D (mutant) | ||
**[[1k56]], [[2k02]] - PaBlac Pse-2 | **[[1k56]], [[2k02]] - PaBlac Pse-2 | ||
**[[1g68]], [[1k4f]] – PaBlac Pse-4 | **[[1g68]], [[1k4f]] – PaBlac Pse-4 | ||
**[[1g6a]] – PaBlac Pse-4 (mutant) | **[[1g6a]] – PaBlac Pse-4 (mutant) | ||
**[[1ko2]] – PaBlac Vim-2<br /> | **[[1ko2]] – PaBlac Vim-2 | ||
**[[1k38]] – Blac D – ''Salmonella typhimurium'' | **[[7l5v]], [[7n1m]] - PaBlac D Oxa-935<br /> | ||
**[[1m6k]] – EcBlac D | **[[1k38]] – Blac D – ''Salmonella typhimurium'' | ||
**[[3hbr]] – KpBlac D Oxa-48<br /> | **[[1m6k]] – EcBlac D | ||
**[[ | **[[3if6]], [[4s2p]] - KpBlac D Oxa-46 | ||
**[[3hbr]], [[6hoo]], [[7ass]], [[7lxg]] – KpBlac D Oxa-48 | |||
**[[6i5d]], [[6rj7]], [[8pea]], [[8peb]], [[8pec]] - KpBlac D Oxa-48 (mutant)<br /> | |||
**[[6huh]] - KpBlac D Oxa-427<br /> | |||
**[[6hb8]] - KpBlac D Oxa-517<br /> | |||
**[[6n6w]], [[6n6t]] - AbBlac D Oxa-23 (mutant)<br /> | **[[6n6w]], [[6n6t]] - AbBlac D Oxa-23 (mutant)<br /> | ||
**[[4zdx]] - AbBlac D Oxa-51<br /> | **[[4zdx]] - AbBlac D Oxa-51<br /> | ||
**[[4y0o]] - AbBlac D Oxa-58<br /> | **[[4y0o]] - AbBlac D Oxa-58<br /> | ||
**[[6t1h]] - AbBlac D Oxa-66<br /> | |||
**[[6nz8]] - AbBlac D Oxa-231<br /> | |||
**[[4s2l]], [[5odz]] - EncBlac D Oxa-163<br /> | **[[4s2l]], [[5odz]] - EncBlac D Oxa-163<br /> | ||
**[[4ied]] – Blac – ''Fusobacterium nucleatum''<br /> | **[[4ied]] – Blac – ''Fusobacterium nucleatum''<br /> | ||
**[[5e2f]], [[6w5e]] – BsBlac D <br /> | |||
**[[6nlw]] – Blac D – ''Shewanella oneidensis''<br /> | **[[6nlw]] – Blac D – ''Shewanella oneidensis''<br /> | ||
**[[6nhs]] – Blac D – | **[[6nhs]] – Blac D – Nostoc<br /> | ||
**[[6nhu]] – Blac D – ''Agrobacterium fabrum''<br /> | **[[6nhu]] – Blac D – ''Agrobacterium fabrum''<br /> | ||
**[[6ni0]] – BtBlac D <br /> | **[[6ni0]] – BtBlac D <br /> | ||
**[[6n1n]] – Blac D – ''Sebaldella termitidis''<br /> | **[[6n1n]] – Blac D – ''Sebaldella termitidis''<br /> | ||
**[[6ue2]] – Blac D – ''Peptoclostridium difficile''<br /> | |||
**[[6wy4]], [[7rl8]] – CdBlac D – ''Clostridium difficile''<br /> | |||
**[[7rlr]] – CdBlac D (mutant) <br /> | |||
**[[6w5g]] – BaBlac D – ''Bacillus atrophaeus''<br /> | |||
**[[6w5o]] – BaBlac D (mutant) <br /> | |||
**[[7k3m]] – CpBlac D <br /> | |||
* | *beta-lactamase class D binary complex | ||
**[[1k6s]] - PaBlac D + phenylboronic acid | **[[1k6s]] - PaBlac D + phenylboronic acid | ||
**[[1dd6]], [[1h5x]], [[1h8y]], [[2wgv]] - PaBlac D + inhibitor | **[[1dd6]], [[1h5x]], [[1h8y]], [[2wgv]] - PaBlac D + inhibitor | ||
**[[3isg]] – EcBlac D + inhibitor | **[[3isg]] – EcBlac D + inhibitor | ||
**[[4s2m]] - EncBlac D Oxa-163+ inhibitor<br /> | **[[4s2m]] - EncBlac D Oxa-163+ inhibitor<br /> | ||
**[[3pae]], [[3pag]], [[4f94]] - AbBlac D (mutant) + inhibitor | **[[7khy]], [[7khz]] - EncBlac D Oxa-163 (mutant) + drug<br /> | ||
**[[3pae]], [[3pag]], [[4f94]] - AbBlac D (mutant) + inhibitor | |||
**[[3znt]], [[4y0u]], [[4y0t]] - AbBlac D + inhibitor<br /> | **[[3znt]], [[4y0u]], [[4y0t]] - AbBlac D + inhibitor<br /> | ||
**[[6mpq]], [[6b22]] - AbBlac D Oxa-24 + inhibitor<br /> | **[[6mpq]], [[6b22]] - AbBlac D Oxa-24 + inhibitor<br /> | ||
**[[8cul]], [[8cuo]] - AbBlac D Oxa-24 + boronic acid inhibitor<br /> | |||
**[[5vfd]] - AbBlac D Oxa-24 (mutant) + inhibitor<br /> | **[[5vfd]] - AbBlac D Oxa-24 (mutant) + inhibitor<br /> | ||
**[[5fat]], [[5fas]], [[5faq]], [[5fap]], [[5fao]], [[5dva]], [[5dtt]], [[5dts]], [[5dtk]], [[5qa4]], [[5qa5]], [[5qa6]], [[5qa7]], [[5qa8]], [[5qa9]], [[5qaa]], [[5qab]], [[5qac]], [[5qad]], [[5qae]], [[5qaf]], [[5qag]], [[5qah]], [[5qai]], [[5qaj]], [[5qak]], [[5qal]], [[5qam]], [[5qan]], [[5qao]], [[5qap]], [[5qaq]], [[5qar]], [[5qas]], [[5qat]], [[5qau]], [[5qav]], [[5qaw]], [[5qax]], [[5qay]], [[5qaz]], [[5qb0]], [[5qb1]], [[5qb2]], [[5qb3]], [[5qb4]] | **[[5fat]], [[5fas]], [[5faq]], [[5fap]], [[5fao]], [[5dva]], [[5dtt]], [[5dts]], [[5dtk]], [[5qa4]], [[5qa5]], [[5qa6]], [[5qa7]], [[5qa8]], [[5qa9]], [[5qaa]], [[5qab]], [[5qac]], [[5qad]], [[5qae]], [[5qaf]], [[5qag]], [[5qah]], [[5qai]], [[5qaj]], [[5qak]], [[5qal]], [[5qam]], [[5qan]], [[5qao]], [[5qap]], [[5qaq]], [[5qar]], [[5qas]], [[5qat]], [[5qau]], [[5qav]], [[5qaw]], [[5qax]], [[5qay]], [[5qaz]], [[5qb0]], [[5qb1]], [[5qb2]], [[5qb3]], [[5qb4]], [[6uvk]], [[6v1o]], [[7ass]], [[7aux]], [[7aw5]], [[7jhq]], [[7k5v]], [[7l8o]], [[7r6z]], [[8faj]], [[8sqf]], [[8sqg]] - KpBlac D Oxa-48 + inhibitor<br /> | ||
* | *beta-lactamase class D binary complex with antibiotics | ||
**[[1k6r]], [[1k54]] - PaBlac D + antibiotic | **[[1k6r]], [[1k54]], [[7l5t]] - PaBlac D + antibiotic | ||
**[[2wgi]], [[2wkh]] - PaBlac D (mutant) + antibiotic<br /> | **[[2wgi]], [[2wkh]] - PaBlac D (mutant) + antibiotic | ||
**[[7t7g]] - AbBlac D Oxa-23 + antibiotic<br /> | |||
**[[6n6x]], [[6n6y]], [[6n6v]], [[6n6u]] - AbBlac D Oxa-23 (mutant) + antibiotic<br /> | **[[6n6x]], [[6n6y]], [[6n6v]], [[6n6u]] - AbBlac D Oxa-23 (mutant) + antibiotic<br /> | ||
**[[7rpg]], [[7rpe]], [[7rpf]] - AbBlac D Oxa-24 + antibiotic<br /> | |||
**[[7rp8]], [[7rp9]], [[7rpa]], [[7rpb]], [[7rpc]], [[7rpd]] - AbBlac D Oxa-24 (mutant) + antibiotic<br /> | |||
**[[7vvi]], [[7vx3]], [[7vx6]] - AbBlac D Oxa-58 + antibiotic<br /> | |||
**[[8sq7]] - AbBlac D Oxa-82 (mutant) + antibiotic<br /> | |||
**[[8sq8]] - AbBlac D Oxa-109 + antibiotic<br /> | |||
**[[4x56]] - AbBlac D Oxa-160 + antibiotic<br /> | **[[4x56]] - AbBlac D Oxa-160 + antibiotic<br /> | ||
**[[4x53]] - AbBlac D Oxa-160 (mutant) + antibiotic<br /> | **[[4x53]] - AbBlac D Oxa-160 (mutant) + antibiotic<br /> | ||
**[[4x55]] - AbBlac D Oxa-225 (mutant) + antibiotic<br /> | **[[4x55]] - AbBlac D Oxa-225 (mutant) + antibiotic<br /> | ||
**[[4mll]] - KpBlac D Oxa-1 + antibiotic<br /> | **[[4mll]] - KpBlac D Oxa-1 + antibiotic<br /> | ||
**[[4s2j]], [[4s2k]], [[4s2n]], [[4wmc]] - KpBlac D Oxa-48 + antibiotic<br /> | **[[4s2j]], [[4s2k]], [[4s2n]], [[4wmc]], [[6pqi]], [[6psg]], [[6pt1]], [[6pt5]], [[6ptu]], [[7kh9]], [[7khq]] - KpBlac D Oxa-48 + antibiotic<br /> | ||
**[[6pxx]], [[7kh9]] - KpBlac D Oxa-48 (mutant) + antibiotic<br /> | |||
**[[7khy]] - KpBlac D Oxa-163 + antibiotic<br /> | |||
**[[6xj3]], [[8qnz]] - KpBlac D + antibiotic<br /> | |||
**[[8ep6]] – CpBlac + antibiotic – ''Chitinophaga pinensis''<br /> | |||
* | *AmpC beta-lactamase | ||
**[[1ke4]], [[2bls]], [[2zj9]], [[3bls]], [[5gzw]] – EcBlac | **[[1ke4]], [[2bls]], [[2zj9]], [[3bls]], [[5gzw]], [[6t3d]], [[7cin]] – EcBlac | ||
**[[1l0d]], [[1l0e]], [[1l0f]], [[1l0g]], [[4kg6]], [[5joc]] - EcBlac (mutant) | **[[1l0d]], [[1l0e]], [[1l0f]], [[1l0g]], [[4kg6]], [[5joc]] - EcBlac (mutant) | ||
**[[ | **[[6lc7]] - EncBlac <br /> | ||
**[[4gzb]], [[4wz4]], [[4wyy]] – PaBlac<br /> | **[[4gzb]], [[4wz4]], [[4wyy]] – PaBlac<br /> | ||
**[[4net]] – AbBlac<br /> | **[[4net]] – AbBlac<br /> | ||
Line 367: | Line 456: | ||
**[[5e2g]] – Blac – ''Burkholderia cenocepacia''<br /> | **[[5e2g]] – Blac – ''Burkholderia cenocepacia''<br /> | ||
* | *AmpC beta-lactamase binary complex | ||
**[[3f9o]] - AhBlac B – ''Aeromonas hydrophila'' | **[[1fcn]] – EcBlac (mutant) + substrate | ||
**[[3fai]], [[1x8h]], [[3sw3]], [[3t9m]] - AhBlac B (mutant)<br /> | **[[1iel]], [[1fcm]], [[1iem]], [[1kvm]], [[1ll5]], [[1ll9]], [[1llb]], [[4kz3]], [[4kz4]], [[4okp]], [[4olg]], [[4jxg]], [[6t35]], [[6t5y]], [[6tbw]], [[9c6p]]- EcBlac + antibiotic | ||
**[[ | **[[1fco]], [[1i5q]], [[1kvl]], [[4ken]], [[4kg2]], [[4kg5]], [[4kg6]], [[4kz3]], [[4kz4]], [[4kg9]], [[4kz5]], [[4kz6]], [[4kz7]], [[4kz8]], [[4kza]], [[4kzb]] - EcBlac (mutant) + antibiotic | ||
**[[ | **[[1fsw]], [[1fsy]], [[1kds]], [[1kdw]], [[1ke0]], [[1ke3]], [[1mxo]], [[1my8]], [[2i72]], [[4e3i]], [[4e3j]], [[4e3k]], [[4e3l]], [[4e3m]], [[4e3n]], [[4e3o]], [[4lv0]], [[4lv1]], [[4lv2]], [[4lv3]], [[4oqg]], [[6yeo]], [[6ypd]] - EcBlac + boronic acid inhibitor | ||
**[[ | **[[1pi4]], [[1pi5]], [[2ffy]] - EcBlac (mutant) + boronic acid inhibitor | ||
**[[ | **[[1l2s]], [[1xgi]], [[1xgj]], [[2hdq]], [[2hdr]], [[2hds]], [[2hdu]], [[2p9v]], [[2pu2]], [[2pu4]], [[2r9w]], [[2r9x]], [[2rcx]], [[4jxs]], [[4jxv]], [[4jxw]], [[4old]], [[6dpz]], [[6dpy]], [[6dpx]], [[6dpt]], [[6t7l]], [[6tpm]], [[9c81]], [[9c83]], [[9c84]], [[9dhl]] - EcBlac + inhibitor | ||
**[[ | **[[1o07]], [[4kz9]] - EcBlac (mutant) + inhibitor | ||
**[[ | **[[6lc8]], [[6lc9]], [[7ti1]] - EncBlac + inhibitor<br /> | ||
**[[ | **[[4xux]] - EncBlac + boronic acid inhibitor<br /> | ||
**[[4hef]], [[4nk3]], [[4x68]] - PaBlac + inhibitor<br /> | |||
**[[3s1y]], [[3s22]] - PaBlac (mutant) + inhibitor | |||
**[[6s1s]], [[8sdr]], [[8sdt]] - PaBlac + boronic acid inhibitor<br /> | |||
*Carbapenemase | |||
**[[3f9o]] - AhBlac B – ''Aeromonas hydrophila'' | |||
**[[3fai]], [[1x8h]], [[3sw3]], [[3t9m]] - AhBlac B (mutant) | |||
**[[6p96]] - KpBlac Oxa-48 <br /> | |||
**[[7o5t]], [[7o9n]], [[7peh]] - KpBlac D<br /> | |||
**[[7pgo]] - KpBlac D (mutant)<br /> | |||
**[3rxw]], [[3rxx]], [[2ov5]], [[5ul8]] – KpBlac Kpc-2 | |||
**[[6xd5]], [[7ljk]], [[7lk8]], [[7tb7]], [[7tbx]] - KpBlac Kpc-2 (mutant)<br /> | |||
**[[6qwd]] - KpBlac Kpc-3<br /> | |||
**[[6qwe]] - KpBlac Kpc-4<br /> | |||
**[[6z21]], [[6z22]] - KpBlac Kpc-4 (mutant)<br /> | |||
**[[8tjm]], [[8tn0]] - KpBlac Kpc-44<br /> | |||
**[[4eqi]] – SfBlac Sfc-1 | |||
**[[4jf5]], [[4jf6]] - AbBlac Oxa-23 <br /> | **[[4jf5]], [[4jf6]] - AbBlac Oxa-23 <br /> | ||
**[[4oh0]], [[4z9q]] - AbBlac Oxa-58 <br /> | **[[4oh0]], [[4z9q]] - AbBlac Oxa-58 <br /> | ||
**[[5boh]] - AbBlac Oxa-58 (mutant)<br /> | **[[5boh]] - AbBlac Oxa-58 (mutant)<br /> | ||
Line 385: | Line 491: | ||
**[[1bue]] – EncBlac<br /> | **[[1bue]] – EncBlac<br /> | ||
**[[4tze]], [[4tzb]] - EcBlac Ndm-5<br /> | **[[4tze]], [[4tzb]] - EcBlac Ndm-5<br /> | ||
**[[6ogo]] - EcBlac Ndm-9<br /> | |||
**[[3dw0]], [[3c5a]] - EcBlac Kpc-2 <br /> | **[[3dw0]], [[3c5a]] - EcBlac Kpc-2 <br /> | ||
**[[8ehu]] – ChBlac A – ''Chromobacterterium haemolyticum''<br /> | |||
* Carbapenemase binary complexes | |||
**[[6p97]], [[6p98]], [[6p99]], [[6p9c]], [[6pk0]] - KpBlac Oxa-48 + antibiotic<br /> | |||
**[[67dml]] - KpBlac Oxa-48 + inhibitor<br /> | |||
**[[5eec]], [[6td1]], [[7utb]] - KpBlac Kpc-2 + boronic acid inhibitor<br /> | |||
**[[4zbe]], [[6b1y]], [[6b1x]], [[6b1w]], [[6b1j]], [[6b1h]], [[6b1f]], [[6d15]], [[6d16]], [[6d17]], [[6d18]], [[6d19]], [[6j8q]], [[6jn3]], [[6jn4]], [[6jn5]], [[6m7i]], [[6mey]], [[6mll]], [[6mnp]], [[6qw9]], [[6td0]], [[6v1j]], [[7vqn]], [[7ti2]], [[7u8s]], [[7u9b]], [[7ua7]] - KpBlac Kpc-2 + inhibitor<br /> | |||
**[[5uj3]], [[5uj4]], [[6v7i]], [[7a61]], [[7pep]], [[7tc1]] - KpBlac Kpc-2 + antibiotic<br /> | |||
**[[6xd7]], [[6z23]], [[6z25]], [[7llb]], [[7llh]], [[7lnl]], [[7lr9]], [[7pse]], [[7psf]], [[8aki]], [[8akj]], [[8akk]], [[8akl]], [[8akm]], [[8g2r]], [[8g2t]] - KpBlac Kpc-2 (mutant) + antibiotic<br /> | |||
**[[6qwa]] - KpBlac Kpc-3 + inhibitor<br /> | |||
**[[6qwb]], [[6qwc]] - KpBlac Kpc-4 + inhibitor<br /> | |||
**[[8tmr]], [[8tmt]] - KpBlac Kpc-44 + antibiotic<br /> | |||
**[[6tt8]], [[6ttc]], [[7uox]], [[7uoy]] - KpBlac NDM-1 + inhibitor<br /> | |||
**[[6lip]], [[6liz]], [[6lj0]], [[6lj1]], [[6lj2]], [[6lj4]], [[6lj5]], [[6lj6]], [[6lj7]], [[6lj8]], [[8sko]] - KpBlac NDM-1 + drug<br /> | |||
**[[8skp]] - KpBlac NDM-4 + inhibitor<br /> | |||
**[[4euz]], [[4ev4]] – SfBlac Sfc-1 (mutant) + antibiotic | |||
**[[4jf4]] - AbBlac Oxa-23 + antibiotic<br /> | |||
**[[7t7e]] - AbBlac Oxa-23 + inhibitor<br /> | |||
**[[5ll7]] - EcBlac Kpc-2 + boronic acid inhibitor<br /> | **[[5ll7]] - EcBlac Kpc-2 + boronic acid inhibitor<br /> | ||
**[[6mkq]], [[6mk6]] - Blac + inhibitor – ''Vibrio cholerae''<br /> | **[[6mkq]], [[6mk6]] - Blac + inhibitor – ''Vibrio cholerae''<br /> | ||
**[[5mgi]] - KoBlac Kpc-2 + boronic acid inhibitor - ''Klebsiella oxytoca'' <br /> | |||
**[[8ek9]] – ChBlac A + antibiotic <br /> | |||
Non-classified beta-lactamase | |||
**[[1bsg]] – Blac – ''Streptomyces albus''<br /> | **[[1bsg]] – Blac – ''Streptomyces albus'' | ||
**[[1alq]], [[1blp]], [[1dja]], [[1djb]], [[1djc]], [[1ghi]] – SaBlac (mutant) | **[[6wgr]] - SaBlac <br /> | ||
**[[1gce]], [[1xx2]] - EncBlac <br /> | **[[1alq]], [[1blp]], [[1dja]], [[1djb]], [[1djc]], [[1ghi]] – SaBlac (mutant) | ||
**[[4fr7]], [[4fsb]] - EncBlac Vim-31 (mutant)<br /> | **[[1gce]], [[1xx2]] – EncBlac | ||
**[[6op6]], [[6op7]] - EncBlac Vim-20<br /> | |||
**[[4fr7]], [[4fsb]] - EncBlac Vim-31 (mutant)<br /> | |||
**[[5hfo]] - EcBlac Oxa-232<br /> | **[[5hfo]] - EcBlac Oxa-232<br /> | ||
**[[1dy6]] – SmBlac Sme-1 | **[[1dy6]] – SmBlac Sme-1 | ||
**[[1fr1]], [[1fr6]] – CfBlac | **[[1fr1]], [[1fr6]] – CfBlac | ||
**[[1i2s]], [[4blm]] – BlBlac | **[[1i2s]], [[4blm]] – BlBlac | ||
**[[2gdn]], [[3zhh]], [[5oyo]], [[5nj2]] – MtBlac | **[[2gdn]], [[3zhh]], [[5oyo]], [[5nj2]], [[7k8l]] – MtBlac | ||
**[[4whi]] – MtBlac C terminal<br /> | **[[4whi]] – MtBlac C terminal<br /> | ||
**[[4jlf]], [[6h28]], [[6h27]] - MtBlac (mutant)<br /> | **[[4jlf]], [[6h28]], [[6h27]],[[7a5u]], [[7a5w]], [[8r88]], [[8rfz]] - MtBlac (mutant)<br /> | ||
**[[2jc7]], [[3g4p]] – AbBlac | **[[2jc7]], [[3g4p]] – AbBlac | ||
**[[3byd]] – KoBlac | **[[3byd]] – KoBlac | ||
**[[3i7j]] – Blac – ''Mycobacterium bovis'' | **[[3i7j]] – Blac – ''Mycobacterium bovis'' | ||
**[[3lez]] – Blac – ''Oceanobacter iheyensis'' | **[[3lez]] – Blac – ''Oceanobacter iheyensis'' | ||
**[[3p09]] – Blac – ''Francisella tularensis'' | **[[3p09]] – Blac – ''Francisella tularensis'' | ||
**[[4ewf]] – Blac – ''Sphaerobacter thermophilus'' | **[[4ewf]] – Blac – ''Sphaerobacter thermophilus'' | ||
**[[3w4o]], [[3w4p]], [[4efz]] – Blac – ''Burkholderia pseudomallei''<br /> | **[[3w4o]], [[3w4p]], [[4efz]] – Blac – ''Burkholderia pseudomallei''<br /> | ||
**[[3w4q]] – | **[[3w4q]] – BmBlac – ''Burkholderia multivorans''<br /> | ||
**[[7d5j]] – BmBlac (mutant)<br /> | |||
**[[5ihv]] – Blac – ''Burkholderia ambifaria''<br /> | **[[5ihv]] – Blac – ''Burkholderia ambifaria''<br /> | ||
**[[5hx9]], [[5hw3]] – Blac – ''Burkholderia vietnamiensis''<br /> | **[[5hx9]], [[5hw3]] – Blac – ''Burkholderia vietnamiensis''<br /> | ||
Line 415: | Line 546: | ||
**[[5evl]] – Blac – ''Chromobacterterium violaceum''<br /> | **[[5evl]] – Blac – ''Chromobacterterium violaceum''<br /> | ||
**[[5e43]] – Blac – ''Streptoporangium roseum''<br /> | **[[5e43]] – Blac – ''Streptoporangium roseum''<br /> | ||
**[[5e2e]] – | **[[5e2e]] – YeBlac <br /> | ||
**[[4k0w]] – AbBlac Oxa-23 (mutant)<br /> | **[[4k0w]] – AbBlac Oxa-23 (mutant)<br /> | ||
**[[4k0x]] – AbBlac Oxa-23 <br /> | **[[4k0x]] – AbBlac Oxa-23 <br /> | ||
Line 423: | Line 554: | ||
**[[5oe2]] – KpBlac Oxa-245 <br /> | **[[5oe2]] – KpBlac Oxa-245 <br /> | ||
**[[6gth]] – KpBlac <br /> | **[[6gth]] – KpBlac <br /> | ||
**[[7oda]] – Blac Oxa-436 – ''Enterobacter asburiae'' <br /> | |||
**[[3wrt]] – ChBlac – ''Chromohalobacter''<br /> | **[[3wrt]] – ChBlac – ''Chromohalobacter''<br /> | ||
**[[3wrz]], [[3ws0]], [[3ws1]], [[3ws2]], [[3ws3]], [[3ws4]], [[3ws5]] – ChBlac (mutant)<br /> | **[[3wrz]], [[3ws0]], [[3ws1]], [[3ws2]], [[3ws3]], [[3ws4]], [[3ws5]] – ChBlac (mutant)<br /> | ||
**[[6njk]] – Blac – ''Sulfitobacter''<br /> | **[[6njk]] – Blac – ''Sulfitobacter''<br /> | ||
**[[6n9k]] – EcBlac <br /> | **[[6n9k]], [[6x9y]], [[8jb7]] – EcBlac <br /> | ||
**[[6n36]] – | **[[6v3q]] – PaBlac Fim-1<br /> | ||
**[[6v3u]] – ElBlac Fim-1 <br /> | |||
**[[6n36]], [[6v4w]] – CpBlac <br /> | |||
**[[6mu9]] – Blac – ''Bacillus megaterium''<br /> | **[[6mu9]] – Blac – ''Bacillus megaterium''<br /> | ||
**[[6ch0]], [[6cgy]] – AaBlac – ''Alicyclobacillus acidoterrestris''<br /> | **[[6ch0]], [[6cgy]] – AaBlac – ''Alicyclobacillus acidoterrestris''<br /> | ||
**[[6edm]], [[7lno]], [[7lnr]], [[7me9]] – CdBlac <br /> | |||
**[[6izc]] – VpBlac – ''Vibrio parahaemolyticus''<br /> | |||
**[[6izd]] – VpBlac (mutant)<br /> | |||
**[[6wgp]] – Blac – ''Xanthomonas campestris''<br /> | |||
**[[6wgq]] – Blac – ''Shigella flexneri''<br /> | |||
**[[6whl]] – Blac – ''Legionella pneumophila''<br /> | |||
**[[6wjm]] – Blac – ''Desulfarculus baarsii''<br /> | |||
Non-classified beta-lactamase binary complex | |||
**[[1ghm]], [[1ghp]], [[1pio]] - SaBlac (mutant) + antibiotic | |||
**[[1blc]], [[1blh]] – SaBlac + inhibitor | |||
**[[1ghm]], [[1ghp]], [[1pio]] - SaBlac (mutant) + antibiotic | **[[1bls]] – EncBlac + phosphonate derivative | ||
**[[1blc]], [[1blh]] – SaBlac + inhibitor | **[[1bul]] - EncBlac + penicillin derivative | ||
**[[1bls]] – EncBlac + phosphonate derivative | **[[1ga0]] - EncBlac + inhibitor | ||
**[[1bul]] - EncBlac + penicillin derivative | **[[1i2w]] – BlBlac + cifoxitin | ||
**[[1ga0]] - EncBlac + inhibitor | **[[3cg5]], [[4q8i]], [[4qb8]], [[7k8e]], [[7k8f]], [[7k8h]], [[7k8k]], [[8ec4]], [[8ecf]] – MtBlac + antibiotic | ||
**[[1i2w]] – BlBlac + cifoxitin | **[[3n8s]], [[3ny4]], [[3n6i]], [[3n7w]], [[3n8l]], [[3n8r]], [[3nbl]], [[3nc8]], [[3nck]], [[3nde]], [[3ndg]] - MtBlac (mutant) + antibiotic | ||
**[[3cg5]], [[4q8i]], [[4qb8]] – MtBlac + antibiotic | **[[3dwz]], [[3iqa]], [[3m6b]], [[3m6h]], [[4df6]], [[6h2k]], [[6h2i]], [[6h2h]], [[6h2g]], [[6h2c]] – MtBlac + inhibitor | ||
**[[3n8s]], [[3ny4]], [[3n6i]], [[3n7w]], [[3n8l]], [[3n8r]], [[3nbl]], [[3nc8]], [[3nck]], [[3nde]], [[3ndg]] - MtBlac (mutant) + antibiotic | |||
**[[3dwz]], [[3iqa]], [[3m6b]], [[3m6h]], [[4df6]], [[6h2k]], [[6h2i]], [[6h2h]], [[6h2g]], [[6h2c]] – MtBlac + inhibitor | |||
**[[4x6t]], [[4qhc]] – MtBlac (mutant) + inhibitor<br /> | **[[4x6t]], [[4qhc]] – MtBlac (mutant) + inhibitor<br /> | ||
**[[3vff]], [[3vfh]], [[4ebl]], [[4ebn]], [[4ebp]] – MtBlac (mutant) + intermediate | **[[3vff]], [[3vfh]], [[4ebl]], [[4ebn]], [[4ebp]] – MtBlac (mutant) + intermediate | ||
**[[6h2a]] – MtBlac (mutant) + protein<br /> | **[[6h2a]] – MtBlac (mutant) + protein<br /> | ||
**[[3fv7]], [[3fyz]], [[3fzc]], [[3mbz]] – AbBlac + inhibitor<br /> | **[[3fv7]], [[3fyz]], [[3fzc]], [[3mbz]] – AbBlac + inhibitor | ||
**[[8cum]], [[8cup]], [[8cuq]], [[8fqq]], [[8fqs]], [[8fqu]] – AbBlac + boronic acid inhibitor<br /> | |||
**[[7t7d]], [[7t7f]] – AbBlac Oxa-23 + inhibitor<br /> | |||
**[[4wm9]] – AbBlac Oxa-24 + antibiotic <br /> | **[[4wm9]] – AbBlac Oxa-24 + antibiotic <br /> | ||
**[[6q5b]], [[6q5f]] – KpBlac Oxa-48 (mutant) + | **[[8hxn]] – SfBlac + inhibitor<br /> | ||
**[[8v9g]] – KpBlac Ges-5 + inhibitor<br /> | |||
**[[6q5b]], [[6q5f]] – KpBlac Oxa-48 (mutant) + inhibitor<br /> | |||
**[[6uqs]], [[6uqt]], [[6uqu]], [[6ur3]] – PaBlac (mutant) + boronic acid inhibitor<br /> | |||
*[[6yrp]], [[7a5z]] - PaBlac Vim-2 + drug<br /> | |||
**[[6cgz]] – AaBlac + lactone derivative<br /> | **[[6cgz]] – AaBlac + lactone derivative<br /> | ||
**[[7kep]], [[7keq]], [[7ker]], [[7lnq]], [[7mea]], [[7meb]], [[7mec]], [[7med]], [[7mee]], [[7mef]], [[7meg]], [[7meh]] – CdBlac + drug<br /> | |||
**[[6pqc]] – CdBlac (mutant) + antibiotic <br /> | |||
**[[7doo]] – BmBlac + antibiotic <br /> | |||
**[[7ddm]] – BmBlac + peptide <br /> | |||
*Serine beta-lactamase (ClbP) | |||
**[[7mde]], [[7mdf]] – EcClbP (mutant)<br /> | |||
**[[7ul6]] – EcClbP – Cryo EM <br /> | |||
**[[3o3v]] – EcClbP peptidase domain 38-372<br /> | |||
**[[4e6w]], [[4e6x]], [[7mdc]] – EcClbP + boronic acid inhibitor<br /> | |||
**[[7v1y]] – EcClbP + peptide + inhibitor<br /> | |||
**[[8pc9]], [[8pca]], [[8pcb]], [[8pcc]], [[8pcd]], [[8pce]], [[[8pcf]], [8pcg]], [[8pci]], [[8pcj]], [[8pck]], [[8pcl]], [[8pcm]], [[8pcn]], [[8pcp]], [[8pcq]], [[8pcr]], [[8pcs]], [[8pct]], [[8pcu]], [[8pcv]] – KpClbP CTX-M-14 + bo | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Latest revision as of 10:23, 15 January 2025
3D Structures of Beta-lactamase3D Structures of Beta-lactamase
Updated on 15-January-2025
Non-classified beta-lactamase
- 1bsg – Blac – Streptomyces albus
- 6wgr - SaBlac
- 1alq, 1blp, 1dja, 1djb, 1djc, 1ghi – SaBlac (mutant)
- 1gce, 1xx2 – EncBlac
- 6op6, 6op7 - EncBlac Vim-20
- 4fr7, 4fsb - EncBlac Vim-31 (mutant)
- 5hfo - EcBlac Oxa-232
- 1dy6 – SmBlac Sme-1
- 1fr1, 1fr6 – CfBlac
- 1i2s, 4blm – BlBlac
- 2gdn, 3zhh, 5oyo, 5nj2, 7k8l – MtBlac
- 4whi – MtBlac C terminal
- 4jlf, 6h28, 6h27,7a5u, 7a5w, 8r88, 8rfz - MtBlac (mutant)
- 2jc7, 3g4p – AbBlac
- 3byd – KoBlac
- 3i7j – Blac – Mycobacterium bovis
- 3lez – Blac – Oceanobacter iheyensis
- 3p09 – Blac – Francisella tularensis
- 4ewf – Blac – Sphaerobacter thermophilus
- 3w4o, 3w4p, 4efz – Blac – Burkholderia pseudomallei
- 3w4q – BmBlac – Burkholderia multivorans
- 7d5j – BmBlac (mutant)
- 5ihv – Blac – Burkholderia ambifaria
- 5hx9, 5hw3 – Blac – Burkholderia vietnamiensis
- 5vpq – Blac – Burkholderia phymatum
- 5evl – Blac – Chromobacterterium violaceum
- 5e43 – Blac – Streptoporangium roseum
- 5e2e – YeBlac
- 4k0w – AbBlac Oxa-23 (mutant)
- 4k0x – AbBlac Oxa-23
- 6goa – AbBlac Oxa-48 (mutant)
- 5oft – KpBlac Oxa-48 (mutant)
- 5oe0 – KpBlac Oxa-181
- 5oe2 – KpBlac Oxa-245
- 6gth – KpBlac
- 7oda – Blac Oxa-436 – Enterobacter asburiae
- 3wrt – ChBlac – Chromohalobacter
- 3wrz, 3ws0, 3ws1, 3ws2, 3ws3, 3ws4, 3ws5 – ChBlac (mutant)
- 6njk – Blac – Sulfitobacter
- 6n9k, 6x9y, 8jb7 – EcBlac
- 6v3q – PaBlac Fim-1
- 6v3u – ElBlac Fim-1
- 6n36, 6v4w – CpBlac
- 6mu9 – Blac – Bacillus megaterium
- 6ch0, 6cgy – AaBlac – Alicyclobacillus acidoterrestris
- 6edm, 7lno, 7lnr, 7me9 – CdBlac
- 6izc – VpBlac – Vibrio parahaemolyticus
- 6izd – VpBlac (mutant)
- 6wgp – Blac – Xanthomonas campestris
- 6wgq – Blac – Shigella flexneri
- 6whl – Blac – Legionella pneumophila
- 6wjm – Blac – Desulfarculus baarsii
Non-classified beta-lactamase binary complex
- 1ghm, 1ghp, 1pio - SaBlac (mutant) + antibiotic
- 1blc, 1blh – SaBlac + inhibitor
- 1bls – EncBlac + phosphonate derivative
- 1bul - EncBlac + penicillin derivative
- 1ga0 - EncBlac + inhibitor
- 1i2w – BlBlac + cifoxitin
- 3cg5, 4q8i, 4qb8, 7k8e, 7k8f, 7k8h, 7k8k, 8ec4, 8ecf – MtBlac + antibiotic
- 3n8s, 3ny4, 3n6i, 3n7w, 3n8l, 3n8r, 3nbl, 3nc8, 3nck, 3nde, 3ndg - MtBlac (mutant) + antibiotic
- 3dwz, 3iqa, 3m6b, 3m6h, 4df6, 6h2k, 6h2i, 6h2h, 6h2g, 6h2c – MtBlac + inhibitor
- 4x6t, 4qhc – MtBlac (mutant) + inhibitor
- 3vff, 3vfh, 4ebl, 4ebn, 4ebp – MtBlac (mutant) + intermediate
- 6h2a – MtBlac (mutant) + protein
- 3fv7, 3fyz, 3fzc, 3mbz – AbBlac + inhibitor
- 8cum, 8cup, 8cuq, 8fqq, 8fqs, 8fqu – AbBlac + boronic acid inhibitor
- 7t7d, 7t7f – AbBlac Oxa-23 + inhibitor
- 4wm9 – AbBlac Oxa-24 + antibiotic
- 8hxn – SfBlac + inhibitor
- 8v9g – KpBlac Ges-5 + inhibitor
- 6q5b, 6q5f – KpBlac Oxa-48 (mutant) + inhibitor
- 6uqs, 6uqt, 6uqu, 6ur3 – PaBlac (mutant) + boronic acid inhibitor
- 6yrp, 7a5z - PaBlac Vim-2 + drug
- Serine beta-lactamase (ClbP)
- 7mde, 7mdf – EcClbP (mutant)
- 7ul6 – EcClbP – Cryo EM
- 3o3v – EcClbP peptidase domain 38-372
- 4e6w, 4e6x, 7mdc – EcClbP + boronic acid inhibitor
- 7v1y – EcClbP + peptide + inhibitor
- 8pc9, 8pca, 8pcb, 8pcc, 8pcd, 8pce, [[[8pcf]], [8pcg]], 8pci, 8pcj, 8pck, 8pcl, 8pcm, 8pcn, 8pcp, 8pcq, 8pcr, 8pcs, 8pct, 8pcu, 8pcv – KpClbP CTX-M-14 + bo
- 7mde, 7mdf – EcClbP (mutant)