Crystal structure of the metallo-beta-lactamase NDM-1 in complex with a bisthiazolidine inhibitorCrystal structure of the metallo-beta-lactamase NDM-1 in complex with a bisthiazolidine inhibitor

Structural highlights

4u4l is a 4 chain structure with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BLAN1_KLEPN Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.

See Also

4u4l, resolution 1.90Å

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