Aminotransferase 3D structures

3D structures of Aminotransferase3D structures of Aminotransferase

Updated on 29-September-2024

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• Histidinol-phosphate aminotransferase
  • 8bj4 – bmHPA – barrel medic
    
  • 8bj3 – bmHPA + PLP
    
  • 8bj1, 8bj2 – bmHPA + PLP derivative
    
  • 1gew, 1iji – EcHPA + PLP – Escherichia coli
    
  • 1gey, 1fg7 – EcHPA + PLP derivative
    
  • 1gex, 1fg3 – EcHPA + PLP + histidinol-phosphate
    
  • 1uu0 – TmHPA + phosphate – Thermotoga maritima
    
  • 1uu1 – TmHPA + PLP derivative + histidinol-phosphate
    
  • 1h1c – TmHPA + PLP
    
  • 1uu2, 2f8j – TmHPA + PLP derivative
    
  • 3cq4 – CgHPA – Corynebacterium glutamicum
    
  • 8ht4 – CgHPA + PLP
    
  • 3cq5, 3cq6 – CgHPA + PLP derivative
    
  • 3ffh – HPA – Listeria innocua
    
  • 3ftb – HPA + phosphate – Clostridium acetobutylicum
    
  • 3hdo – HPA – Geobacter metallireducens
    
  • 4rae – MtHPA – Mycobacterium tuberculosis
    
  • 4r8d, 5c6u, 5yhv – MtHPA + PLP
    
  • 7szp – KpHPA + PLP – Klebsiella pneumoniae
    
• Ornithine aminotransferase
  • 1oat, 7ta1 – hOA + PLP – human
    
  • 1gbn, 2can, 5vwo, 6oia, 6v8c, 6v8d, 7lnm, 7lom, 7lon, 7ted, 7tev, 7tfp, 8v9m – hOA + PLP + inhibitor
    
  • 2oat – hOA + PLP derivative
    
  • 2byj, 2byl – hOA (mutant) + PLP
    
  • 7jx9 – hOA + intermediate + inhibitor
    
  • 7ta0 – hOA + aminovaleric acid
    
  • 5eav – TgOA – Toxoplasma gondii
    
  • 5eqc, 4zwm – TgOA + PLP
    
  • 5e5i – TgOA + inactivator
    
  • 5e3k – TgOA + pentanoic acid derivative
    
  • 5dj9 – TgOA + gabaculine
    
• Acetylornithine aminotransferase
  • 2ord, 2e54 – TmACOAT + PLP
    
  • 2eh6 – ACOAT + PLP – Aquifex aeolicus
    
  • 3nx3 – CjACOAT – Campylobacter jejuni
    
  • 5viu – ACOAT – Elizabethkingia anophelis
    
  • 6w7x – ACOAT (mutant) – Stenotrophomonas maltophila
    
  • 4jev – StACOAT + PLP derivative – Salmonella typhimurium
    
  • 4jey – StACOAT (mutant) + PLP
    
  • 4jf0, 4f01 – StACOAT (mutant) + PLP derivative
    
  • 4jew, 4jex, 4jez – StACOAT (mutant) + canaline
    
• Succinylornithine aminotransferase
  • 4ade – EcSOAT
    
  • 4adb, 4adc – EcSOAT + PLP
    
  • 4add – EcSOAT + PLP + succinylornithine
    
• Aspartate Aminotransferase
• Phosphoserine aminotransferase
• Alanine glyoxylate aminotransferase or serine-pyruvate aminotransferase or 3-hydroxykynurenine transaminase
  • 1h0c, 2yob, 5f9s, 5og0, 6rv1 – hAGA + PLP
    
  • 4cbr, 4cbs, 5ofy, 5luc – hAGA (mutant) + PLP
    
  • 1j04, 5hhy, 6rv0 – hAGA + PLP derivative
    
  • 4i8a – hAGA (mutant) + PLP derivative
    
  • 3r9a – hAGA + PLP derivative + peroxisomal targeting signal receptor
    
  • 4kxk, 4kyo – hAGA (mutant) + peroxisomal targeting signal receptor
    
  • 6mfb – AaAGA + PLP – Aedes aegypti
    
  • 2huf – AaAGA + PLP derivative
    
  • 2hui – AaAGA + PLP derivative + glyoxylate
    
  • 2huu – AaAGA + PLP derivative + alanine
    
  • 6pk3 – AtAGA + PLP – Arabidopsis thaliana
    
  • 6pk1 – AtAGA + PLP + pyruvate
    
  • 1vjo – AGA + PLP - Nostoc
    
• D-amino acid aminotransferase
  • 1a0g - BaAAT + PLP derivative – Bacillus
    
  • 1daa, 4daa - BaAAT + PLP
    
  • 2dab, 1g2w - BaAAT (mutant) + PLP
    
  • 2daa, 3daa - BaAAT + PLP derivative
    
  • 5daa - BaAAT (mutant) + PLP derivative
    
  • 3lqs - BaAAT + thiophenecarboxylic acid
    
  • 4m0j - BtAAT – Burkholderia thailandensis
    
  • 4tm5 - BtAAT + PLP
    
  • 8ayk, 8onm - AcAAT + PLP derivative – Aminobacterium colombiense
    
  • 8ahr - AcAAT + PLP
    
  • 8onj, 8onl - AcAAT (mutant) + PLP
    
  • 8ayj - AcAAT + PLP + aminooxypropionic acid
    
  • 8onn - AcAAT (mutant) + PLP + aminooxypropionic acid
    
  • 8aie - AcAAT + PLP derivative + cyclo-Ser
    
• Branched chain amino acid aminotransferase
  • 1ekf, 1ekp, 1ekv – hBCAT + PLP
    
  • 2hdk, 2hgw, 2hgx, 2hhf, 5mpr, 6prx – hBCAT (mutant) + PLP
    
  • 1kt8, 1kta – hBCAT + PLP derivative
    
  • 2alh, 5bwr, 5bwt, 5bwu, 5bwv, 5bwx, 5bww, 5cr5 – hBCAT + PLP + inhibitor
    
  • 5i60, 5i5y, 5i5x, 5i5w, 5i5v, 5i5u, 5i5t, 5i5s, 5hne – hBCAT + PLP + biaryl amide
    
  • 2hg8 – hBCAT (mutant) + PLP + methylleucine
    
  • 4chi – AfBCAT + PLP – Aspergillus fumigatus
    
  • 4uug – AfBCAT + inhibitor
    
  • 4cmd – NhBCAT + PLP – Nectria haematococca
    
  • 4cmf – NhBCAT + inhibitor
    
  • 5cm0 – GaBCAT + PLP – Geoglobus acetivorans
    
  • 5e25 – GaBCAT + PLP + ketoglutarate
    
  • 5ce8 – TuBCAT + PLP – Thermoproteus uzoniensis
    
  • 6thq – TuBCAT + PLP + norvaline
    
  • 5u3f – MtBCAT + cycloserine
    
  • 6nst - PaBCAT (mutant) – Pseudomonas aeruginosa
    
  • 6jif – PaBCAT + PLP
    
  • 6gkr – TteBCAT + PLP – Thermobaculum terrenum
    
  • 7nea – TtBCAT (mutant) + PLP
    
  • 6q8e – TteBCAT + PLP derivative
    
  • 6h65 – TteBCAT + PLP – Haliangium ochraceum
    
  • 4whx – BpBCAT + PLP – Burkholderia pseudomallei
    
  • 7lv7 – BCAT – Giardia lamblia
    
  • 7p3t – BCAT + PLP – Luminiphilus syltensis
    
  • 8ioz – MvBCAT – Mycobacterium vanbaalenii
    
  • 8ivp – MvBCAT + PLP derivative
    
  • 8isc – MvBCAT (mutant) + PLP derivative
    
  • 8pnw, 8pny – BCAT + PLP – Blastococcus saxobsidens
    
• Aromatic amino acid aminotransferase
  • 1ay4 – PdAROAT + PLP – Paracoccus dentrificans
    
  • 1ay5 – PdAROAT + PLP + maleic acid
    
  • 1ay8, 1ay1 – PdAROAT + PLP + cinnamic acid derivative
    
  • 2ay2, 2ay3, 2ay4, 2ay5 – PdAROAT + PLP + propionic acid derivative
    
  • 2ay6, 2ay7, 2ay8 – PdAROAT + PLP + butyric acid derivative
    
  • 2ay9 – PdAROAT + PLP + valeric acid derivative
    
  • 4eff – BpAROAT – Burkholderia pseudomallei
    
  • 4f4e – BpAROAT + PLP derivative
    
  • 4rkc – PsAROAT + PLP derivative - Psychrobacter
    
  • 4rkd – PsAROAT + PLP derivative + PLP
    
  • 6hnb – CaAROAT – Candida albicans
    
  • 6hnu – CaAROAT + PLP + Phe
    
• Tyrosine aminotransferase
  • 3dyd – hTYRAT + PLP
    
  • 3pdx – mTYRAT + PLP derivative – mouse
    
  • 3tat – EcTYRAT + PLP
    
  • 3fsl – EcTYRAT (mutant) + PLP derivative
    
  • 1bw0 – TYRAT + PLP derivative – Trypanosoma cruzi
    
  • 4ix8 – TYRAT + PLP derivative – Leishmania infantum
    
• Tryptophan aminotransferase
  • 3bwn, 3bwo – AtTRYAT + PLP derivative
    
• Beta-phenylalanine aminotransferase
  • 4ao9 – VpPHEAT + PLP – Variovorax paradoxus
    
  • 4aoa – VpPHEAT + PLP derivative
    
• Alanine aminotransferase
  • 3ihj – hALAAT 2 + PLP
    
  • 3tcm – ALAAT 2 (mutant) + PLP derivative - barley
    
• Cysteine aminotransferase
  • 4w91 – CYSAT + PLP – Brucella suis
    
• Glutamine aminotransferase
  • 1v2d – TtGLNAT + PLP – Thermus thermophilus
    
  • 1v2e – TtGLNAT + PLP + keto-methylthiobutyrate
    
  • 1v2f – TtGLNAT + PLP + phenylpropionate
    
• Lysine aminotransferase
  • 2cin – MtLYSAT + PLP
    
  • 2jje – MtLYSAT (mutant) + PLP
    
  • 2jjf – MtLYSAT (mutant)
    
  • 2cjd – MtLYSAT + PLP + lysine
    
  • 2jjg – MtLYSAT + PLP + inhibitor
    
  • 2cjg – MtLYSAT + PLP derivative
    
  • 2cjh – MtLYSAT + PLP + oxoglutarate
    
  • 2jjh – MtLYSAT (mutant) + PLP + oxoglutarate
    
• Gamma-aminobutyrate aminotransferase or 4-aminobutyrate aminotransferase
  • 4zsy, 4zsw, 4y0i, 4y0h, 4y0d, 6b6g – GABA + inactivator - pig
    
  • 1sf2, 7jh3 – EcGABA + PLP
    
  • 1sff – EcGABA + PLP derivative
    
  • 1szk, 1szs, 1szu – EcGABA (mutant) + PLP derivative
    
  • 3r4t – GABA + PLP derivative – Mycobacterium marinum
    
  • 4ffc – GABA + PLP derivative – Mycobacterium abscessus
    
  • 6wj8 – GABA + PLP derivative – Klebsiella pneumoniae
    
• ArnB aminotransferase
  • 1mdo - StArnB + PLP derivative
    
  • 1mdx – StArnB + PLP + oxoglutarate
    
  • 1mdz – StArnB + PLP + PLP derivative
    
• PseC aminotransferase
  • 2fni - HpPseC + PLP – Helicobacter pylori
    
  • 2fn6 - HpPseC + phosphate
    
  • 2fnu - HpPseC + PLP derivative + uridine derivative
    
  • 3hbm - CjPseC (mutant)
    
  • 3hbn - CjPseC (mutant) + UDP
    
• TlmJ aminotransferase
  • 5uid - TlmJ + PLP – Streptoalloteichus hindustanus
    
• WbpE aminotransferase
  • 3nu7, 3nu8, 3nub, 3nyu - PaWbpE + PLP derivative
    
  • 3nys - PaWbpE (mutant) + PLP
    
  • 3nyt - PaWbpE (mutant) + PLP derivative
    
• Alpha-aminoadipate aminotransferase or kynurenine/alpha-aminoadipate aminotransferase
  • 6t8p, 6t8q - hAADAT + PLP derivative + inhibitor
    
  • 4je5 - AADAT + PLP derivative + PLP - yeast
    
  • 2egy, 5eun - TtAADAT + PLP
    
  • 3cbf, 2zyj - TtAADAT + PLP derivative
    
  • 2zp7, 2z1y - TtAADAT + PLP + leucine
    
• Broad specificity aminotransferase
  • 4wb0 - BsAT – Leishmania mexicana
    
• Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
  • 6ge8 - MtDAPA
    
  • 4w1x, 4w1w, 4w1v, 4xjl, 4xjm, 4xjo, 4xjp, 4wya, 4wyc, 4wyd, 4wye, 4wyf, 4wyg, 4xew - MtDAPA + PLP + inhibitor
    
  • 4mqr, 4mqq, 4mqp - MtDAPA + inhibitor
    
  • 5uc7 - DAPA + PLP derivative – Citrobacter rodentium
    
  • 5te2 - MbDAPA + inhibitor – Mycobacterium bovis
    
  • 5kgs, 5kgt - MbDAPA + PLP + inhibitor
    
• Putrescine aminotransferase
  • 4uoy - EcPAT + PLP
    
  • 4uox - EcPAT + PLP + putrescine
    
  • 6gwi - PAT + PLP – Halomonas elongata
    
• Omega amino acid-pyruvate aminotransferase
  • 4uho, 4uhn, 4uhm - PaOAAT + PLP
    
• C-6’ aminotransferase or GenB
  • 6cbo – MeGenB1 – Micromonospora echinospora
    
  • 5z83 – MeGenB1 + PLP
    
  • 5z8a – MeGenB1 + PLP + JI-20A
    
  • 5z8k – MeGenB1 + PLP + neomycin
    
  • 7lm0 – MeGenB3 + PLP
    
  • 7lle – MeGenB4 + PLP
    
  • 7lld – MeGenB4 + PLP-sisomicin
    
• Kynurenine aminotransferase
  • 4wlh, 4wlj, 4wp0 – hKAT 1 + PLP derivative
    
  • 5efs, 6d0a – hKAT 2
    
  • 5tf5 – hKAT 2 + PLP derivative + inhibitor
    
  • 5vep, 5veq, 5ver – mKAT 3 + PLP derivative
    
  • 5veh – AaKAT + PLP derivative
    
• Diaminopelargonic acid aminotransferase
  • 6erk – DPAAT + PLP – Psychrobacter cryohalolentis
    
  • 6ed7 – EcDPAAT + PLP + inhibitor
    
• D-phenylglycine aminotransferase
  • 6dvs – PsDPGAT – Pseudomonas stutzeri
    
  • 6g1f – PsDPGAT + PLP derivative
    
• Aminopentol aminotransferase
  • 6hbs – SmAPAT + PLP – Sphingopykis macrogoltabida
    
  • 6hbv – SmAPAT + PLP + PLP derivative
    
• Taurine:2-oxoglutamate aminotransferase
  • 6jix – TOGAT + PLP + Glu – Bifidobacterium kashiwanohense
    
• Diaminopimelate aminotransferase
  • 6oxm – DPAT – Verrucomicrobium spinosum
    
• Glutamine-fructose-6-phosphate aminotransferase
  • 6r4f – hGFPAT + G6P
    
  • 6r4g – hGFPAT + G6P + UDP-GlcNAc
    
  • 6svp – hGFPAT + Glu + G6P + UDP-GlcNAc
    
  • 6r4j – hGFPAT (mutant) + Glu + G6P + UDP-GlcNAc
    
  • 6svm – hGFPAT + Glu + G6P + UDP-GlcNAc + inhibitor
    
  • 6r4h, 6svq – hGFPAT + Glu + G6P
    
  • 6svo – hGFPAT + Glu + G6P derivative
    
  • 6r4i – hGFPAT (mutant) + Glu + G6P
    
  • 6r4e, 6zmk – hGFPAT + PLP + Glu + G6P
    
• Aminotransferase
  • 7vrx – AT + PLP derivative – tomato
    
  • 6l1l – BsAT + PLP – Bacillus subtilis
    
  • 6l1n – BsAT + PLP + Gly
    
  • 6l1o – BsAT + PLP + PLP derivative + Tyr
    
  • 6qp1 – ShAT + inhibitor – Staphylococcus hominis
    
  • 6qp2 – ShAT + PLP + polyHis
    
  • 6t3v – PsAT + PLP + substrate analog
    
  • 6u7a – MtAT + PLP + PLP derivative + kynurenine
    
• Aminotransferase class I/II or PLP-dependent aminotransferase
  • 3op7, 3p6k – AT + PLP derivative – Streptococcus suis
    
  • 8tn2 – ShAT + PLP – Streptomyces hygroscopicus
    
  • 8tn3 – ShAT + PLP derivative
    
  • 7pq9 – AcAT – Alkalihalobacillus clausii
    
  • 7zla, 7zn5, 7zpa, 7zth – AcAT + DNA – Cryo EM
    
  • 7kz3, 7kz6 – BcAT + PLP derivative – Bacillus cereus
    
  • 7kz5 – BcAT + PLP derivative + kanosamine-6-phosphate
    
  • 7kzd – BcAT + PLP derivative + glutarate
    
• Aminotransferase class II
  • 5z0q – AT2 + PLP – Erwinia tasmaniensis
    
• Aminotransferase class III
  • 5ghg, 5ghf – AT3 + PLP derivative – Orchrobactrum anthropi
    
  • 5m46 – RfAT3 + PLP – Rhizobium freirei
    
  • 5m49 – RfAT3 + PLP + azepan derivative
    
  • 5m4b, 5m4d – RfAT3 (mutant) + azepan derivative
    
  • 6k8h – AT3 + PLP derivative – Sphaerobacter thermophilus
    
  • 6io1 – AT3 + PLP derivative – Thermomicrobium roseum
    
• Aminotransferase class IV
  • 4tvi – AT4 + PLP derivative – Brucella abortus
    
  • 7z79 – VpAT4 + PLP
    
  • 7p8o, 8yrt, 8yru – HhAT4 – Haliscomenobacter hydrossis
    
  • 7p7x – HhAT4 + PLP
    
  • 8raf – HhAT4 (mutant) + PLP
    
  • 8ahu – HhAT4 + cyclo-Ser
    
  • 8yrv – HhAT4 + aminooxypropionic acid
    
  • 8rai – HhAT4 + phenylhydrazine
    
  • 8ahu – AT4 + cyclo-Ser – Haliscomenobacter hydrossis
    
• Aminotransferase class V
  • 5f8v – AT5 + PLP derivative – Trichomonas vaginalis
    
  • 9aza – AT5 + PLP – Penicillium expansum