6ed7

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Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor MAC13772Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor MAC13772

Structural highlights

6ed7 is a 8 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:bioA, EL75_3021, EL79_3111, EL80_3072 ("Bacillus coli" Migula 1895)
Activity:Adenosylmethionine--8-amino-7-oxononanoate transaminase, with EC number 2.6.1.62
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A0A0GYM0_ECOLX] Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.[HAMAP-Rule:MF_00834]

6ed7, resolution 2.43Å

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OCA