Transcription initiation factors 3D structures

3D structures of transcription initiation factors3D structures of transcription initiation factors

Updated on 08-December-2020 - For a general description of the protein see Transcription initiation factor

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• TFIIA
  • 5m4s – hTFIIA – human
    
  • 6mzm – hTFIIA+TFIID + TBP + DNA – Cryo EM
    
  • 1nvp – hTFIIA + TBP + DNA
    
  • 5fur – hTFIIA + hTFIIF + TBP + DNA - CryoEM
    
  • 1ytf, 1nh2, 1rm1 – yTFIIA + TBP + DNA – yeast
    
• TFIIB
  • 1tfb – hTFIIB - NMR
    
  • 1dl6 - hTFIIB N terminal – NMR
    
  • 5wh1 - hTFIIB C terminal
    
  • 1rly - hTFIIB Zn ribbon domain + Zn – NMR
    
  • 1ro4 - hTFIIB Zn ribbon domain – NMR
    
  • 1ais, 1d3u - TFIIB C terminal + TBP + DNA – Pyrococcus woesei
    
  • 1pft – PfTFIIB N terminal – Pyrococcus furiosus – NMR
    
  • 5o9j, 5o9i - TFIIB – Methanocaldococcus jannaschii
    
• TFIIA+TFIIB
  • 6o9l – hTFIIA+TFIIB in RNA polymerase II – Cryo EM
    
• TFIIIB
  • 5n9g – hTFIIIB + TBP + DNA
    
  • 6f44, 6f42, 6f41, 6f40, 6eu0, 6cnf, 6cnd, 6cnc, 6cnb – yTFIIIB + RNA polymerase III – Cryo EM
    
• TFIIIC see Transcription factor tau
• TFIID
  • 1bh8 – hTFIID
    
  • 1eqf – hTFIID subunit 1
    
  • 6fic – hTFIID subunit 1 + inhibitor
    
  • 3uv5 – hTFIID subunit 1 bromodomain 1-2
    
  • 3uv4 – hTFIID subunit 1 bromodomain 2 1501-1635
    
  • 6bqd, 5mg2, 6p38, 6p3a, 6p39 – hTFIID subunit 1 bromodomain 2 + inhibitor
    
  • 3aad – hTFIID subunit 1 bromodomain 1-2 + histone chaperone ASF1A
    
  • 5mg2 – hTFIID subunit 1 bromodomain 2 + inhibitor
    
  • 4yym, 4yyn – hTFIID subunit 1 bromodomain 2 + histone peptide
    
  • 5i1q, 5i29 – hTFIID subunit 1 bromodomain 2 + pyrrolopyridone
    
  • 5c13, 5wxg, 5wxh, 5mxy – hTFIID subunit 3 PHD finger + histone peptide
    
  • 5wxh – hTFIID subunit 3 PHD finger + histone peptide
    
  • 4wv4 - hTFIID subunits 8+10
    
  • 4grw - hTFIID subunits 1+7
    
  • 6f3t - hTFIID subunits 5+6+9
    
  • 6mzl - hTFIID subunits 1-13 + TBP – Cryo EM
    
  • 6mzd - hTFIID subunits 1,3-6,9-13 + TBP – Cryo EM
    
  • 6mzc - hTFIID subunits 2,4-6,8-12 – Cryo EM
    
  • 1bh9 – hTFIID + PCMBS
    
  • 6df7, 6df4 – TFIID subunit 1 bromodomain 2 + inhibitor - rabbit
    
  • 1tba – TFIID – Drosophila melanogaster - NMR
    
  • 1qn3, 1qn4, 1qn5, 1qn6, 1qn7, 1qn8, 1qn9, 1qna, 1qnb, 1qnc, 1qne – TFIID + DNA – Arabidopsis thaliana
    
  • 4oy2 - yTFIID subunits 1+7
    
  • 6mip - yTFIID subunits 14
    
  • 6lqz - yTFIID subunit 14 + STH1EBMC - NMR
    
  • 5iok, 5d7e, 6miq, 6mio, 6min – yTFIID subunit 14 YEATS domain 1-137 + histone peptide
    
  • 6t9j - yTFIID subunit 12 + Spt20 + transcription-associated protein – Cryo EM
    
  • 6t9k, 6t9i - yTFIID in SAGA complex – Cryo EM
    
  • 6tbm, 6tb4, 6hqa - TFIID in SAGA complex – Komagataella phaffii – Cryo EM
    
• TFIIE
  • 5gpy - hTFIIE subunits α 1-217+β 141-217
    
  • 1vd4 - hTFIIE Zn finger domain 113-174 – NMR
    
  • 2rnq – hTFIIE C terminal 378-439 - NMR
    
  • 2rnr – hTFIIE C terminal + TFIIH PH domain- NMR
    
  • 6xjf, 6pln – PfTFIIE-a
    
• TFIIF
  • 1f3u – hTFIIF
    
  • 1nha – hTFIIF C terminal - NMR
    
  • 1i27 – hTFIIF C terminal (mutant)
    
  • 1j2x – hTFIIF C terminal + RNA polymerase CTD phosphatase peptide
    
  • 1onv – hTFIIF C terminal + serine phosphatase peptide - NMR
    
  • 2k7l – hTFIIF C terminal + FCP1 peptide - NMR
    
• TFIIH
  • 5ivw, 6o9m – hTFIIH in preinitiation complex – Cryo EM
    
• TF in RNA polymerase II
  • 5iy6, 5iy7, 5iy8, 5iy9, 5iya, 5iyb, 5iyc, 5iyd – hTFIIA + hTFIIB + hTFIIE + hTFIIF + hTFIIH + DNA – Cryo EM
    
  • 5fyw – yTFIIA + yTFIIE + yTFIIF + DNA
    
  • 5fz5, 6gym, 6gyl – yTFIIA + yTFIIE + yTFIIF + DNA – Cryo EM
    
  • 6gyk – yTFIIA + yTFIIB + yTFIIF + DNA – Cryo EM
    
  • 5sva – yTFIIA + yTFIIB + yTFIIE + yTFIIF + DNA – Cryo EM
    
  • 4v1o, 4v1n – yTFIIB + yTFIIF – Cryo EM
    
  • 3k1f, 3k7a, 4bbr, 4bbs – yTFIIB
    
  • 5fmf, 5oqj, 5oqm – yTFIIA + yTFIIB + yTFIIE + yTFIIF + yTFIIH + DNA – Cryo EM
    
  • 6kf4, 6kf9 – TFIIF – Thermococcus kodakarensis - Cryo EM
    
• TF RRN or RNA polymerase I-specific transcription initiation factor RRN
  • 3tj1 – yTF RRN3
    
  • 5g5l – yTF RRN3 in RNA polymerase I
    
  • 6rrd, 6rqt – yTF RRN3 in RNA polymerase I – Cryo EM
    
  • 5o7x – yTF RRN6+RRN7+RRN11
    
  • 6ruo – yTF RRN3+RRN6+RRN11 in RNA polymerase I – Cryo EM
    
  • 5w66, 5w65, 5w64, 5w5y, 5oa1 – yTF RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM
    
  • 6rwe, 6rui, 6rql, 6rqh, 5n61, 5n60, 5n5z, 5n5y – yTF RRN3+RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM