1pft

N-TERMINAL DOMAIN OF TFIIB, NMRN-TERMINAL DOMAIN OF TFIIB, NMR

Structural highlights

1pft is a 1 chain structure with sequence from Pyrococcus furiosus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TF2B_PYRFU Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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