ATPase
ATPase is an enzyme which catalyzes the breakdown of ATP into ADP and a phosphate ion. This dephosphorylation releases energy which the enzyme uses to drive other reactions. ATPase types include:
ATPase domains include metal-binding domain (MBD) and nucleotide-binding domain (NBD). For more details see:
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3D Printed Physical Model of ATP Synthase3D Printed Physical Model of ATP Synthase
Shown below is a 3D printed physical model of the Respiration Electron Transport Chain. Complex I is colored red, complex II is purple, complex III is green, complex IV is blue and the atp synthase protein is colored orange, yellow and red.
The MSOE Center for BioMolecular ModelingThe MSOE Center for BioMolecular Modeling
The MSOE Center for BioMolecular Modeling uses 3D printing technology to create physical models of protein and molecular structures, making the invisible molecular world more tangible and comprehensible. To view more protein structure models, visit our Model Gallery.
3D Structures of ATPase3D Structures of ATPase
Updated on 10-May-2018
V-ATPaseV-ATPase
- V-ATPase subunit A
(mutant)
- V-ATPase subunit B
- V-ATPase subunit C
- 1u7l, 3u2f, 3u2y, 3u32, 3ud0 - yATPS subunit C
- 3v3c - ATPS subunit C - pea
- 1ijp, 1l6t – EcF1-ATPS subunit C (mutant) – Escherichia coli - NMR
- 1r5z, 1v9m - TtATPS subunit C – Thermus thermophilus
- 3lg8 - MtATPS subunit C C-terminal
- 2w5j - sATPS subunit C - spinach
- 2wie, 2xqs, 2xqt, 2xqu - ATPS subunit C – Arthrospira platensis
- 3zk1, 3zk2 - ATPS subunit C – Fusobacterium nucleatum<br />
- 1u7l, 3u2f, 3u2y, 3u32, 3ud0 - yATPS subunit C
- V-ATPase subunit D+F
- 4rnd – yATPase subunit D+F
- 4rnd – yATPase subunit D+F
- V-ATPase subunit E
- V-ATPase subunit F
- V-ATPase subunit G
- V-ATPase subunit H
- 1ho8 – yATPS subunit H
- 1ho8 – yATPS subunit H
- V-ATPase subunit K
- V-ATPase subunit I
- 3rrk – ATPS subunit I N terminal – Meiothermus ruber
- V-ATPase multi subunits
- 4dl0, 4efa - yATPase subunits C,G,E
- 3w3a - yATPS subunit A,B,D,F
- 5tj5 - yATPS subunit A,C,C’,C’’,D,E,F
- 5voz, 5voy, 5vox - yATPS subunit A,C,C’,C’’,D,E,F,H – Cryo EM
- 6c6l - yATPS subunit A,C,C’,C’’,D,E,F + V0 assembly protein 1
- 5bw9 - yATPS subunit A,B,D,E,G,H – Cryo EM
- 5d80 - yATPS subunit A,B,D,E,F,G,H
- 3a5c, 3a5d - TtATPS subunit A,B,D,F
- 5tsj - TtATPS subunit A,B,C,D,E,F,G + antibody - Cryo-EM
- 5gas, 5gar - TtATPS subunit A,B,C,D,E,F,G,I - Cryo-EM
- 5y60. 5y5z, 5y5y, 5y5x - TtATPS subunit A,B,C,D,E,F,I,K - Cryo-EM
- 3gqb - TtATPS subunit A (mutant),B (mutant)
- 3k5b - TtATPS subunit E (mutant)+C
- 5knd, 5knc, 5knb - EhATPS subunit A,B,D,F
- 4dl0, 4efa - yATPase subunits C,G,E
P-ATPaseP-ATPase
- Cu+2 transporting ATPase
- 2kmv, 2kmx, 2arf, 2koy – hATPase NBD – human – NMR
- 2kij - hATPase actuator domain – NMR
- 1yjr, 1yjt, 1yju, 1yjv - hATPase (mutant) 6th soluble domain – NMR
- 1y3j, 1y3k - hATPase 5th soluble domain – NMR
- 2ew9 - hATPase 5th+6th soluble domains – NMR
- 1s6o, 1s6u, 2lqb - hATPase 2nd soluble domain – NMR
- 1q8l - hATPase 2nd MBD – NMR
- 1aw0, 2aw0 - hATPase 4th MBD – NMR
- 1kvi, 1kvj - hATPase 1st MBD – NMR
- 5t7l - hATPase 1st MBD + Cu transport protein
- 3dxs - AtATPase RAN1 MBD (mutant) – Arabidopsis thaliana
- 5lbd – AtATPase PAA1 N-domain
- 5lbk – AtATPase PAA2 N-domain
- 3voy - AfATPase – Archaeoglobus fulgidus – CryoEM
- 3skx, 3sky - AfATPase NBD
- 2k1r - hATPase MBD+ ATOX1 – NMR
- 2rop, 2g9o, 2ga7 - hATPase MBD – NMR
- 2rml - BsATPase N-terminal – Bacillus subtilis – NMR
- 2gcf - sATPase N-terminal - Synechocystis – NMR
- 4a4j - sATPase N-terminal
- 4a48 - sATPase
- 2iye - SsATPase catalytic domain – Sulfolobus solfataricus
- 2yj3 - SsATPase catalytic domain (mutant)
- 2yj4, 2yj5, 2yj6 - SsATPase catalytic domain (mutant) + nucleotide
- 1fvq, 1fvs - hATPase – NMR
- 3cjk – hATPase + Cu transporting protein ATX1
- 3rfu, 4bbj, 4bev, 4byg – LpATPase – Legionella pneumophila
- 4f2f - ATPase metal-binding domain – Streptococcus pneumonia
- 3j08, 3j09 - AfATPase
- 3a1c – AfATPase + AMPPCP
- 3a1d - AfATPase + ADP-Mg
- 3a1e - AfATPase (mutant) + AMPPCP
- 2kmv, 2kmx, 2arf, 2koy – hATPase NBD – human – NMR
- Na/K transporting ATPase
- 3a3y - SaATPase+K+ouabain – Squalus acanthias
- 3kdp, 3b8e – pATPase – pig
- 3n23 – pATPase + ouabain
- 3wgv, 3wgu – pATPase + oligomycin
- 3b8e - pATPase a+BeF3
- 2hc8 –AfATPase CopA A domain
- 2b8e - AfATPase CopA NBD
- 2xze - SaATPase
- 5aw9, 5aw8, 5aw7, 5aw6, 5aw5, 5aw4, 5aw3, 5aw2, **5aw1, 5aw0, 5avz, 5avy, 5avx, 5avw, 5avv, 5avu, 5avt, 5avs, 5avr, 5avq – SaATPase + phospholemman-like protein
- 4xe5 - bATPase
- 1mo8, 1mo7 - rATPase α-1 – rat
- 1q3i - pATPase NBD
- 4ret, 4res, 4hyt, 4hqj - pATPase subunits α,β,γ
- 2zxe - ATPase subunits α,β + phospholemman-like protein – spiny dogfish
- 3a3y - SaATPase+K+ouabain – Squalus acanthias
- Ca+2 transporting ATPase
- 3fgo - rATPase+CPA+AMPPCP – rabbit
- 3b9r, 1xp5 - rATPase+AlF4
- 1wpg - rATPase+MgF4
- 3w5b - rATPase+Mg
- 4h1w, 3w5a - rATPase+ sarcolipin
- 3w5c, 3w5d, 1iwo - rATPase
- 4bew - rATPase+ phosphate analog
- 2zbe, 3b9b – rATPase+BeF3
- 2zbf - rATPase+BeF3+TG
- 2zbg - rATPase+AlF4+TG
- 2zbd, 3ar8 - rATPase+AlF4+nucleotide+Ca
- 3ar9 - rATPase+BeF3+nucleotide
- 2dqs, 3ar2, 1vfp, 4xou - rATPase+AMPPCP
- 5a3r - rATPase + BeF3 + AMPPCP
- 2c88, 2c8k, 3ar4, 3ar3, 3ar5, 3ar7 - rATPase+nucleotide+TG
- 2ear, 2c8l - rATPase+TG
- 2agv - rATPase+TG+BHQ
- 4ycl - rATPase+CPA
- 2eat - rATPase+CPA+GT
- 3ar6 - rATPase+TNP-ADP+GT
- 2eau - rATPase+CPA+curcumin
- 3ba6 - rATPase phosphoenzyme intermediate
- 3fpb - rATPase+ATP+cyclopiazonic acid
- 3fps, 2oa0 - rATPase+ADP+cyclopiazonic acid
- 2o9j - rATPase+MgF4+cyclopiazonic acid
- 1kju, 3n5k - rATPase E2 state
- 2c9m - rATPase Ca2E1 state
- 1t5s, 3n8g - rATPase Ca2E1 state+AMPPCP
- 4nab - rATPase Ca2E1 state (mutant) +AMPPCP
- 1t5t - rATPase Ca2E1 state+ADP+AlF4
- 1su4 - rATPase +2Ca2
- 2by4, 2yfy, 3nal, 3nam, 3nan, 4uu1, 4uu0, 4j2t, **5a3s - rATPase HNE2 state+thapsigargin derivative
- 5a3q - rATPase + thapsigargin derivative + AMPPCP
- 4ycn, 4ycm - rATPase + macrolide
- 4y3u - rATPase + phospholamban
- 3fgo - rATPase+CPA+AMPPCP – rabbit
- Zn+2 transporting ATPase
- K+ transporting ATPase
- As+ transporting ATPase
- 1ii0, 1f48 - EcATPase
- 1ihu – EcATPase+Mg+ADP+AlF3
- 1ii9 - EcATPase
- 3h84, 3idq, 3a36, 3a37 - yATPase GET3
- 4pwx, 5bwk - yATPase GET3 + golgi to ER traffic protein + ubiquitin-like protein
- 5bw8 - yATPase GET3 + golgi to ER traffic protein + ubiquitin-like protein + protein
- 4xwo - yATPase GET3 + antibody + Sec22
- 4xvu - yATPase GET3 + antibody + NYV1
- 4xtr - yATPase GET3 + antibody + pep12p
- 3sja, 3sjb, 3sjc, 3sjd, 3zs8, 3zs9, 3b2e, 3vlc - yATPase GET3 + GET1 cystolic domain
- 1ii0, 1f48 - EcATPase
3ibg - ATPase GET3 – Aspergillus fumigatus
- H+ transporting ATPase
- Na+ transporting ATPase
- H/K transporting ATPase
- Mg+2 transporting ATPase
- 3gwi – EcATPase P-1 NBD
- Arg/ornithine transporting ATPase
- 3md0 – MtATPase+GDP – Mycobacterium tuberculosis
- 1kmh - ATPase alpha subunit+tentoxin – spinach
- 1h8e – cATPase+ADP+AlF4+ADP+SO4 - cow
- 1h8h - cATPase+ AMPPNP
- 1efr - cATPase+efrapeptin
- 3fks – yATPase
- 3ea0 – ATPase ParA, fragment – Chlorobium tepidum
- 2qen – ATPase (mutant) Walker-type – Pyrococcus abyssi
- 3cf0, 3cf1, 3cf3 – mATPase NBD+ADP – mouse
- 3cf2 - mATPase NBD+ADP+AMP-PNP
- 2r31, 2p4x – PdATPase ATP12
- 2zd2 – PdATPase (mutant) ATP12
- 1d8s – EcATPase F1
- 1vdz – PhATPase subunit A – Pyrococcus horikoshii
- 3md0 – MtATPase+GDP – Mycobacterium tuberculosis
- Monosaccharide transporting ATPase
- RNA-dependent ATPase
- 3eaq, 3i31, 3i32 – TtATPase fragment
- 4kbg, 4kbf - TtATPase helicase core domain
- 5mao - TtATPase RRM domain
- 4i69, 4i68 - TtATPase RRM domain (mutant)
- 4i67 - TtATPase RRM domain + RNA
- 3mwj – TtATPase N-terminal (mutant)
- 3mwk, 3nbf – TtATPase N-terminal + 8-oxo-AMP
- 3mwl - TtATPase N-terminal (mutant) + 8-oxoadenine
- 3nej - TtATPase reca-like domain (mutant)
- 3eaq, 3i31, 3i32 – TtATPase fragment
- DNA-dependent ATPase
- 5tnu - ATPase – Sulfolobus tokodaii
- 5tnu - ATPase – Sulfolobus tokodaii
- ATP-dependent ATPase
- Proteasome-associated ATPase
- Transitional endoplasmic reticulum ATPase
- 5c19 – hTer-ATPase (mutant)
- 3hu1, 3hu2, 3hu3, 5ftn, 5ftm, 5ftl, 5ftk, 5ftj – hTer-ATPase + ATPGS
- 4ko8, 4kln, 5dyg, 5c18 – hTer-ATPase (mutant) + ATPGS
- 5dyi – hTer-ATPase + ADP
- 4kod – hTer-ATPase (mutant) + ADP
- 3qc8, 3qq8, 3qwz - hTer-ATPase N terminal + FAS-associated factor 1
- 3qq7 - hTer-ATPase N terminal
- 3tiw - hTer-ATPase N terminal + E3 ubiquitin-protein ligase peptide
- 5c1b - hTer-ATPase N terminal + UFD1--SHP peptide
- 5glf - hTer-ATPase N terminal + derlin-1 peptide
- 5epp - hTer-ATPase N terminal + rhomboid-related protein 4 peptide
- 4kdl, 4kdi - hTer-ATPase N terminal + ubiquitin thioesterase OTU1
- 5b6c - hTer-ATPase N terminal + ubiquitin fusion degradation protein
- 5ifw, 5ifs - hTer-ATPase + tether containing UBX domain
- 5x4l - hTer-ATPase + UBX domain-containing protein
- 5kiy, 5kiw - hTer-ATPase (mutant) + Selenoprotein S
- 1s3s - mTer-ATPase ND1 domain + P47 C terminal
- 4rv0 - Ter-ATPase N terminal + nuclear protein localization protein – Drosophila melanogaster
- 5c19 – hTer-ATPase (mutant)
- Sarcoplasmic/endoplasmic reticulum ATPase
- LAO/AO transport system ATPase
- 3nxs – ATPase – Mycobacterium smegmatis
- DNA double-strand repair ATPase (Rad50)
- 3aux – MjRad50 – Methanocaldococcus jannaschii
- 3auy - MjRad50 + ADP
- 3av0 - MjRad50 + ATP
- 5f3w - MjRad50 + MRE11 + ATPGS
- 5dny - MjRad50 + MRE11 + DNA
- 3qg5 – Rad50 NBD + MRE11 – Thermotoga maritima
- 3qkr, 3qks, 3qf7 - PfRad50 NBD + MRE11 – Pyrococcus furiosus
- 4nck, 4nci, 4nch - PfRad50 NBD (mutant)
- 4ncj - PfRad50 NBD (mutant) + BeF3 + ADP
- 3qkt - PfRad50 NBD + AMPPNP
- 3qku - PfRad50 NBD + AMPPNP + MRE11
- 3aux – MjRad50 – Methanocaldococcus jannaschii
- MipZ ATPase
2xit, 2xj4 – CcMipZ – Caulobacter crescentus
2xj9 – CcMipZ (mutant)
- ATPase Rava
- FlaI ATPase
- The RuvBL1/RuvBL2 complex (ATPase)
- RuvBL1/RuvBL2 complex (ATPase) - Structural and functional insights into a dodecameric molecular machine[1]
- RuvBL1/RuvBL2 complex (ATPase) - Structural and functional insights into a dodecameric molecular machine[1]
ReferencesReferences
- ↑ Gorynia S, Bandeiras TM, Pinho FG, McVey CE, Vonrhein C, Round A, Svergun DI, Donner P, Matias PM, Carrondo MA. Structural and functional insights into a dodecameric molecular machine - The RuvBL1/RuvBL2 complex. J Struct Biol. 2011 Sep 10. PMID:21933716 doi:10.1016/j.jsb.2011.09.001