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Mre11 Rad50 binding domain in complex with Rad50 and AMP-PNPMre11 Rad50 binding domain in complex with Rad50 and AMP-PNP
Structural highlights
FunctionRAD50_PYRFU Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449] See Also |
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