Growth factors: Difference between revisions
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Rabbit <scene name='48/481605/Cv/6'>Phosphoglucose isomerase (autocrine motility factor) active site containing the substrate D-fructose 6-phosphate shows the substrate interacting mainly with residues of one subunit</scene><ref>PMID:11425306</ref>. Water molecules are shown as red spheres. | Rabbit <scene name='48/481605/Cv/6'>Phosphoglucose isomerase (autocrine motility factor) active site containing the substrate D-fructose 6-phosphate shows the substrate interacting mainly with residues of one subunit</scene><ref>PMID:11425306</ref>. Water molecules are shown as red spheres. | ||
*[[Bone morphogenetic protein]]. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. | *[[Bone morphogenetic protein]]. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. | ||
*[[Colony-stimulating factor]] | *[[Colony-stimulating factor]] and [[Colony-stimulating factor receptor]] | ||
The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>. | |||
*[[Epidermal growth factor]] and [[Epidermal Growth Factor Receptor]] | *[[Epidermal growth factor]] and [[Epidermal Growth Factor Receptor]] | ||
*[[Ephrin]] and [[Ephrin receptor]] | *[[Ephrin]] and [[Ephrin receptor]] | ||
Revision as of 16:11, 27 July 2021
ReferencesReferences
- ↑ Mohedas AH, Wang Y, Sanvitale CE, Canning P, Choi S, Xing X, Bullock AN, Cuny GD, Yu PB. Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. J Med Chem. 2014 Oct 9;57(19):7900-15. doi: 10.1021/jm501177w. Epub 2014 Sep 4. PMID:25101911 doi:http://dx.doi.org/10.1021/jm501177w
- ↑ Lee JH, Chang KZ, Patel V, Jeffery CJ. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. PMID:11425306
- ↑ Felix J, De Munck S, Verstraete K, Meuris L, Callewaert N, Elegheert J, Savvides SN. Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1. Structure. 2015 Jul 21. pii: S0969-2126(15)00272-5. doi:, 10.1016/j.str.2015.06.019. PMID:26235028 doi:http://dx.doi.org/10.1016/j.str.2015.06.019