Peroxisome proliferator-activated receptor 3D structures: Difference between revisions

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*'''PPARα'''
*'''PPARα''';Ligand-binding domain 201-468


**[[1k7l]] – hPPARα LBD + G2409544 + NCOA1 - human<br />
**[[1k7l]] – hPPARα + G2409544 + NCOA1 - human<br />
**[[3e94]] – hPPARα LBD + fatty acid activator <br />
**[[3e94]] – hPPARα + fatty acid activator <br />
**[[4bcr]], [[5hyk]] - hPPARα LBD + ligand<br />
**[[4bcr]], [[5hyk]] - hPPARα + ligand<br />
**[[1kkq]] – hPPARα LBD + GW6471 Antagonist + SMRT<br />
**[[1kkq]] – hPPARα + GW6471 Antagonist + SMRT<br />
**[[2npa]] - hPPARα LBD+ propanoic acid derivative + NCOA1<br />
**[[2npa]] - hPPARα + propanoic acid derivative + NCOA1<br />
**[[2p54]] - hPPARα LBD + NCOA1<br />
**[[2p54]] - hPPARα + NCOA1<br />
**[[2rew]] - hPPARα LBD + azetidinone derivative activator<br />
**[[2rew]] - hPPARα + azetidinone derivative activator<br />
**[[2znn]], [[2zno]], [[2znp]], [[2znq]], [[3kdu]], [[3vi8]], [[1i7g]], [[4bcr]], [[5hyk]] - hPPARα LBD+ agonist<br />
**[[2znn]], [[2zno]], [[2znp]], [[2znq]], [[3kdu]], [[3vi8]], [[1i7g]], [[4bcr]], [[5hyk]] - hPPARα + agonist<br />
**[[3fei]], [[3fej]], [[3g8i]], [[3sp6]] - hPPARα LBD+ agonist + NCOA1<br />
**[[3fei]], [[3fej]], [[3g8i]], [[3sp6]] - hPPARα + agonist + NCOA1<br />
**[[3et1]] - hPPARα LBD + NCOA1 + indole derivative
**[[3et1]] - hPPARα + NCOA1 + indole derivative


*'''PPARγ'''
*'''PPARγ''';Ligand-binding domain 202-475


**[[3prg]], [[2qmv]], [[1prg]] – hPPARγ LBD<br />
**[[3prg]], [[2qmv]], [[1prg]] – hPPARγ<br />
**[[6fzy]], [[6fzg]] - hPPARγ LBD (mutant) <br />
**[[6fzy]], [[6fzg]] - hPPARγ (mutant) <br />
**[[2zk0]], [[2zk1]], [[2zk2]], [[2zk3]], [[2zk4]], [[2zk5]], [[2zk6]], [[3vjh]], [[3vji]], [[4e4k]], [[4e4q]], [[4jl4]], [[5hzc]], [[4ci5]], [[4ci4]], [[6an1]], [[2f4b]], [[1zeo]], [[2ath]], [[2hwq]], [[2hwr]], [[2i4j]], [[2q59]], [[2q8s]], [[3b3k]], [[3bc5]], [[3cds]], [[3g9e]], [[3gbk]], [[3gz9]], [[3ia6]], [[3kdt]], [[3an3]], [[3an4]], [[3noa]], [[3r5n]], [[3r8a]], [[3vso]], [[3vsp]], [[2xkw]], [[3b0q]], [[3ho0]], [[3hod]], [[1knu]], [[1i7i]], [[1nyx]], [[2pob]], [[5azv]], [[6f2l]], [[6c5t]], [[6c5q]], [[5wr1]], [[5wr0]], [[5wqx]], [[6md2]], [[6md4]], [[6md1]], [[6md0]], [[6mcz]], [[6k0t]], [[6avi]], [[6aug]] – hPPARγ LBD + ligand <br />
**[[2zk0]], [[2zk1]], [[2zk2]], [[2zk3]], [[2zk4]], [[2zk5]], [[2zk6]], [[3vjh]], [[3vji]], [[4e4k]], [[4e4q]], [[4jl4]], [[5hzc]], [[4ci5]], [[4ci4]], [[6an1]], [[2f4b]], [[1zeo]], [[2ath]], [[2hwq]], [[2hwr]], [[2i4j]], [[2q59]], [[2q8s]], [[3b3k]], [[3bc5]], [[3cds]], [[3g9e]], [[3gbk]], [[3gz9]], [[3ia6]], [[3kdt]], [[3an3]], [[3an4]], [[3noa]], [[3r5n]], [[3r8a]], [[3vso]], [[3vsp]], [[2xkw]], [[3b0q]], [[3ho0]], [[3hod]], [[1knu]], [[1i7i]], [[1nyx]], [[2pob]], [[5azv]], [[6f2l]], [[6c5t]], [[6c5q]], [[5wr1]], [[5wr0]], [[5wqx]], [[6md2]], [[6md4]], [[6md1]], [[6md0]], [[6mcz]], [[6k0t]], [[6avi]], [[6aug]] – hPPARγ + ligand <br />
**[[4l98]], [[4l96]] - hPPARγ LBD (mutant) + ligand<br />
**[[4l98]], [[4l96]] - hPPARγ (mutant) + ligand<br />
**[[3r8i]] - hPPARγ LBD + ureidofibrate derivative<br />
**[[3r8i]] - hPPARγ + ureidofibrate derivative<br />
**[[6o67]], [[6o68]], [[6dgr]], [[6dgq]], [[6dgo]], [[6dgl]], [[6d8x]], [[6c1i]] - hPPARγ LBD + agonist<br />
**[[6o67]], [[6o68]], [[6dgr]], [[6dgq]], [[6dgo]], [[6dgl]], [[6d8x]], [[6c1i]] - hPPARγ + agonist<br />
**[[2g0h]], [[2g0g]], [[2i4p]], [[2i4z]], [[2q5g]], [[2q5p]], [[2q5s]], [[2q61]], [[2q6r]], [[3cdp]], [[3d6d]], [[4em9]], [[4ema]], [[4prg]], [[2q6s]], [[5f9b]], [[4yt1]], [[3wmh]], [[6d3e]]  - hPPARγ LBD+ partial agonist<br />
**[[2g0h]], [[2g0g]], [[2i4p]], [[2i4z]], [[2q5g]], [[2q5p]], [[2q5s]], [[2q61]], [[2q6r]], [[3cdp]], [[3d6d]], [[4em9]], [[4ema]], [[4prg]], [[2q6s]], [[5f9b]], [[4yt1]], [[3wmh]], [[6d3e]]  - hPPARγ + partial agonist<br />
**[[2om9]] - hPPARγ LBD + cannabinoid<br />
**[[2om9]] - hPPARγ + cannabinoid<br />
**[[3b0r]], [[5lsg]], [[4r6s]], [[4r2u]], [[4r06]],  [[6dh9]], [[6dcu]], [[6dbh]] - hPPARγ LBD + antagonist<br />
**[[3b0r]], [[5lsg]], [[4r6s]], [[4r2u]], [[4r06]],  [[6dh9]], [[6dcu]], [[6dbh]] - hPPARγ + antagonist<br />
**[[3osi]], [[3osw]], [[3pba]] - hPPARγ LBD + bisphenol derivative<br />
**[[3osi]], [[3osw]], [[3pba]] - hPPARγ + bisphenol derivative<br />
**[[2p4y]], [[3adt]], [[3adu]], [[3adw]], [[3et3]], [[2hfp]], [[3ty0]] - hPPARγ LBD + modulator<br />
**[[2p4y]], [[3adt]], [[3adu]], [[3adw]], [[3et3]], [[2hfp]], [[3ty0]] - hPPARγ + modulator<br />
**[[2zvt]] - hPPARγ LBD (mutant) + modulator<br />
**[[2zvt]] - hPPARγ (mutant) + modulator<br />
**[[2vsr]], [[2vst]], [[2vv0]], [[2vv1]], [[2vv2]], [[2vv3]], [[2vv4]], [[3x1i]], [[3x1h]], [[3wj5]], [[3wj4]], [[3po9]], [[3sz1]] - hPPARγ LBD + fatty acid activator<br />
**[[2vsr]], [[2vst]], [[2vv0]], [[2vv1]], [[2vv2]], [[2vv3]], [[2vv4]], [[3x1i]], [[3x1h]], [[3wj5]], [[3wj4]], [[3po9]], [[3sz1]] - hPPARγ + fatty acid activator<br />
**[[3ads]], [[3adx]], [[5u5l]], [[4xum]], [[4xuh]], [[4xta]], [[4xld]], [[6d5a]] - hPPARγ LBD + anti-inflammatory drug<br />
**[[3ads]], [[3adx]], [[5u5l]], [[4xum]], [[4xuh]], [[4xta]], [[4xld]], [[6d5a]] - hPPARγ + anti-inflammatory drug<br />
**[[4oj4]] - hPPARγ LBD (mutant) + anti-inflammatory drug<br />
**[[4oj4]] - hPPARγ (mutant) + anti-inflammatory drug<br />
**[[3adv]] - hPPARγ LBD + serotonin<br />
**[[3adv]] - hPPARγ + serotonin<br />
**[[3k8s]], [[3et0]], [[2yfe]], [[4a4v]], [[4a4w]], [[4jaz]], [[5tto]], [[4pwl]], [[4pvu]], [[5y2t]], [[5y2o]], [[5ugm]], [[6dha]] - hPPARγ LBD + antidiabetic drug<br />
**[[3k8s]], [[3et0]], [[2yfe]], [[4a4v]], [[4a4w]], [[4jaz]], [[5tto]], [[4pwl]], [[4pvu]], [[5y2t]], [[5y2o]], [[5ugm]], [[6dha]] - hPPARγ + antidiabetic drug<br />
**[[4o8f]] - hPPARγ LBD (mutant) + antidiabetic drug<br />
**[[4o8f]] - hPPARγ (mutant) + antidiabetic drug<br />
**[[6enq]] - hPPARγ LBD + antifibrotic drug<br />
**[[6enq]] - hPPARγ + antifibrotic drug<br />


*PPARγ complex with polypeptide
*PPARγ complex with polypeptide


**[[1wm0]] –  hPPARγ LBD+ NCAO2 peptide + agonist<br />
**[[1wm0]] –  hPPARγ + NCAO2 peptide + agonist<br />
**[[5dwl]], [[5dvc]], [[5dv8]], [[5dv6]], [[5dv3]], [[5dsh]] - hPPARγ LBD+ NCOA2 peptide + inhibitor<br />
**[[5dwl]], [[5dvc]], [[5dv8]], [[5dv6]], [[5dv3]], [[5dsh]] - hPPARγ + NCOA2 peptide + inhibitor<br />
**[[1zgy]] –  hPPARγ LBD+ antidiabetic drug + nuclear receptor peptide<br />
**[[1zgy]] –  hPPARγ + antidiabetic drug + nuclear receptor peptide<br />
**[[2gtk]], [[3qt0]], [[5gtp]], [[5gto]], [[5gtn]], [[6jq7]], [[6izm]], [[6ilq]], [[6ijs]], [[6ijr]], [[6icj]], [[5ycp]], [[5ycn]] - hPPARγ LBD+ NCOA1 peptide<br />
**[[2gtk]], [[3qt0]], [[5gtp]], [[5gto]], [[5gtn]], [[6jq7]], [[6izm]], [[6ilq]], [[6ijs]], [[6ijr]], [[6icj]], [[5ycp]], [[5ycn]] - hPPARγ + NCOA1 peptide<br />
**[[3cs8]], [[3u9q]]- hPPARγ LBD + PGC-1A peptide<br />
**[[3cs8]], [[3u9q]]- hPPARγ + PGC-1A peptide<br />
**[[3cwd]] - hPPARγ LBD + NCOA1-2 peptide<br />
**[[3cwd]] - hPPARγ + NCOA1-2 peptide<br />
**[[5two]], [[6izn]], [[6fzp]], [[6fzj]], [[6fzf]] - hPPARγ LBD + modulating ligand<br />
**[[5two]], [[6izn]], [[6fzp]], [[6fzj]], [[6fzf]] - hPPARγ + modulating ligand<br />
**[[3fur]], [[3kmg]], [[3v9t]], [[3v9v]], [[3v9y]], [[4f9m]], [[3b1m]], [[3lmp]] - hPPARγ LBD + SRC-1 peptide + modulator<br />
**[[3fur]], [[3kmg]], [[3v9t]], [[3v9v]], [[3v9y]], [[4f9m]], [[3b1m]], [[3lmp]] - hPPARγ + SRC-1 peptide + modulator<br />
**[[4fgy]], [[2prg]] - hPPARγ LBD + antidiabetic agent + NCOA1 peptide<br />
**[[4fgy]], [[2prg]] - hPPARγ + antidiabetic agent + NCOA1 peptide<br />
**[[6ad9]] - hPPARγ LBD + anticancer agent + NCOA1 peptide<br />
**[[6ad9]] - hPPARγ + anticancer agent + NCOA1 peptide<br />
**[[3s9s]], [[3t03]], [[2fvj]]- hPPARγ LBD + NCOA1 peptide + partial agonist<br />
**[[3s9s]], [[3t03]], [[2fvj]]- hPPARγ + NCOA1 peptide + partial agonist<br />
**[[4y29]], [[2fvj]], [[5azt]] - hPPARγ LBD + NCOA1 peptide + ligand<br />
**[[4y29]], [[2fvj]], [[5azt]] - hPPARγ + NCOA1 peptide + ligand<br />
**[[3h0a]] - hPPARγ LBD + SRC 1 + retinoic acid receptor α + retinoic acid + partial agonist<br />
**[[3h0a]] - hPPARγ + SRC 1 + retinoic acid receptor α + retinoic acid + partial agonist<br />
**[[1k74]], [[1rdt]], [[1fm9]] - hPPARγ LBD + NCOA1 + retinoic acid receptor α + retinoic acid + agonist<br />
**[[1k74]], [[1rdt]], [[1fm9]] - hPPARγ + NCOA1 + retinoic acid receptor α + retinoic acid + agonist<br />
**[[5ji0]] - hPPARγ LBD + retinoic acid receptor  + NCOA1 peptide + antidiabetic drug <br />
**[[5ji0]] - hPPARγ + retinoic acid receptor  + NCOA1 peptide + antidiabetic drug <br />
**[[3dzu]], [[3e00]], [[3dzy]] - hPPARγ LBD + DNA + retinoic acid receptor α + NCOA2 peptide + retinoic acid<br />
**[[3dzu]], [[3e00]], [[3dzy]] - hPPARγ + DNA + retinoic acid receptor α + NCOA2 peptide + retinoic acid<br />
**[[1fm6]] - hPPARγ LBD + antidiabetic drug + retinoic acid receptor α + NCOA2 peptide + retinoic acid<br />
**[[1fm6]] - hPPARγ + antidiabetic drug + retinoic acid receptor α + NCOA2 peptide + retinoic acid<br />
**[[3vn2]], [[4hee]], [[4prg]] - hPPARγ LBD + NCOA1 peptide + activator<br />
**[[3vn2]], [[4hee]], [[4prg]] - hPPARγ + NCOA1 peptide + activator<br />
**[[6ms7]] - hPPARγ LBD + PGC1 LXXLL<br />
**[[6ms7]] - hPPARγ + PGC1 LXXLL<br />
**[[6dgp]], [[5z6s]], [[5z5s]] - hPPARγ LBD + coactivator peptide<br />
**[[6dgp]], [[5z6s]], [[5z5s]] - hPPARγ + coactivator peptide<br />
**[[6d94]] - hPPARγ LBD + mediator of RNA polymerase II peptide<br />
**[[6d94]] - hPPARγ + mediator of RNA polymerase II peptide<br />


*'''PPARδ'''
*'''PPARδ''';Ligand-binding domain 171-441


**[[2gwx]] – hPPARδ LBD<br />
**[[2gwx]] – hPPARδ<br />
**[[2env]] – hPPARδ zinc finger domain<br />
**[[2env]] – hPPARδ zinc finger domain 72-146 - NMR<br />
**[[2baw]], [[2b50]], [[2awh]] – hPPARδ + Vaccenic Acid<br />
**[[2baw]], [[2b50]], [[2awh]] – hPPARδ + Vaccenic Acid<br />
**[[3gwx]] – hPPARδ LBD + 5,8,11,14,17-Eicosapentaenoic Acid<br />
**[[3gwx]] – hPPARδ + 5,8,11,14,17-Eicosapentaenoic Acid<br />
**[[3dy6]] – hPPARδ LBD + anthranilic acid <br />
**[[3dy6]] – hPPARδ + anthranilic acid <br />
**[[3et2]], [[1gwx]] – hPPARδ + fatty acid<br />
**[[3et2]], [[1gwx]] – hPPARδ + fatty acid<br />
**[[2j14]], [[2xyj]], [[2xyw]], [[2xyx]], [[3oz0]], [[3sp9]], [[5u3q]], [[5u3r]], [[5u3s]], [[5u3t]], [[5u3u]], [[5u3v]], [[5u3w]], [[5u3x]], [[5u3y]], [[5u3z]], [[5u40]], [[5u41]], [[5u42]], [[5u43]], [[5u44]], [[5u45]], [[1gwx]], [[3tkm]], [[1y0s]], [[5u46]], [[5y7x]] - hPPARδ LBD + agonist<br />
**[[2j14]], [[2xyj]], [[2xyw]], [[2xyx]], [[3oz0]], [[3sp9]], [[5u3q]], [[5u3r]], [[5u3s]], [[5u3t]], [[5u3u]], [[5u3v]], [[5u3w]], [[5u3x]], [[5u3y]], [[5u3z]], [[5u40]], [[5u41]], [[5u42]], [[5u43]], [[5u44]], [[5u45]], [[1gwx]], [[3tkm]], [[1y0s]], [[5u46]], [[5y7x]] - hPPARδ + agonist<br />
**[[3peq]] - hPPARδ LBD + partial agonist<br />
**[[3peq]] - hPPARδ + partial agonist<br />
**[[3d5f]] - hPPARδ LBD + phenoxy derivative<br />
**[[3d5f]] - hPPARδ + phenoxy derivative<br />
**[[5xmx]], [[6a6p]], [[5zxi]] - hPPARδ LBD + inhibitor<br />
**[[5xmx]], [[6a6p]], [[5zxi]] - hPPARδ + inhibitor<br />
}}
}}


[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:52, 21 September 2020

3D Structures of PPAR3D Structures of PPAR

Updated on 21-September-2020

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky
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