Kinesin 3D Structures

3D Structures of Kinesin3D Structures of Kinesin

Updated on 10-May-2024

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• KIF1A, KIF1B, KIF1C or kinesin-3
  • 1bg2 – hKIF MD - human
    
  • 4hna, 4lnu – hKIF1 + Tubulin + designed ankyrin repeat protein + Mg-ADP + GDP + GTP + AlF4
    
  • 4uxy – hKIF1 MD + Tubulin + GDP + GTP – Cryo EM
    
  • 6ojq – hKIF1 MD + Tubulin + G2P + GTP – Cryo EM
    
  • 4uy0 – hKIF1 MD + Tubulin + GDP + GTP + ADP – Cryo EM
    
  • 4uxo, 4uxp, 4uxr, 4uxs, 4uxt - hKIF + tubulin 1B, 2B chains + GDP + GTP – Cryo EM
    
  • 2p4n – hKIF+ Tubulin – EM docking
    
  • 1mkj – hKIF MD+docked FNL
    
  • 6zph – hKIF MD + KIF-binding protein – Cryo EM
    
  • 2wbe – bKIF MD+FNL+Tubulin +AMPPNP – bovine
    
  • 3edl – bKIF MD+ Tubulin – EM
    
  • 4atx - rKIF MD+ Tubulin – rat - Cryo EM
    
• KIF-like 1A, KIF-like 1B, KIF-like 1C
  • 4ejq, 4egx – hKIFL 1A CC1-FHA domain 430-607
    
  • 5lt0, 5lt1, 5lt2, 5lt3, 5lt4 – hKIFL 1 MD (mutant)
    
  • 2g1l – hKIFL 1C FHA domain
    
  • 5wdh – hKIFL 1C MD
    
  • 2eh0 – hKIFL 1B FHA domain – NMR
    
  • 2hxh – pKIFL 1A head+ADP - pig
    
  • 2hxf – pKIFL 1A head+AMPPNP
    
  • 1ia0 – pKIFL 1A MD+Tubulin +ATP
    
  • 2zfi, 2zfj, 2zfk, 2zfl, 2zfm – mKIFL 1A – mouse
    
  • 1vfv, 1vfw – mKIFL 1A MD+Mg-AMPPNP
    
  • 1vfx – mKIFL 1A MD+ADP-Mg-AlFx
    
  • 7eo9, 7eob – mKIFL 1A MD (mutant) +ADP-Mg-AlFx
    
  • 1vfz – mKIFL 1A MD+ADP-Mg-VO4
    
  • 2owm – NcKIFL 1C MD – Neurospora crassa
    
• KIF-like 2A, KIF-like 2C or kinesin-13
  • 2heh, 4ubf – hKIFL 2C
    
  • 2gry – hKIFL 2+ADP
    
  • 6bbn – hKIFL 2A MD + Tubulin + Darpin
    
  • 5mio – hKIFL 2C MD + Tubulin
    
  • 1v8j, 5xja, 5xjb – mKIFL 2C MD+Mg-ADP
    
  • 1i5s – mKIFL 2C MD (mutant)+Mg-ADP
    
  • 1i6i – mKIFL 2C MD (mutant)+Mg-AMPPCP
    
  • 1v8k – mKIFL 2C MD+Mg-AMPPNP
    
  • 2vvg – KIF2 MD – Giardia intestinalis
    
• KIF-like 3B, KIF-like 3C or kinesin-2
  • 3b6u, 3b6v – hKIFL 3B MD
    
  • 5wde – hKIFL 3C+ADP
    
• KIF4A, KIF4B or kinesin-4
  • 3zfc, 3zfd – mKIF4 MD+Mg-AMPPNP
    
• KIF5B, KIF5C or kinesin-1
  • 6ign, 6igv – mKIF5B coiled coil domain 444-566
    
  • 3wrd – mKIF5C
    
  • 3x2t – mKIF5C + ADP
    
  • 3j6h – mKIF5C MD+Mg-GTP + G2P + tubulin
    
  • 3j8x, 3j8y – mKIF5C MD+ GTP + GDP + tubulin
    
  • 2y5w, 2y65 - DmKIF MD – Drosophila melanogasgter
    
  • 4pxt, 4pxu – DmKIF MD (mutant)
    
  • 1n6m – DmKIF MD+FNL
    
  • 3l1c – DmNCD (mutant)
    
• KIF-like 7 or kinesin-4
  • 4a14 – hKIFL 7 MD
    
  • 2xt3 – hKIFL 7 MD (mutant)
    
  • 6mlr – hKIFL 7 MD + Tubulin + GTP + GDP + ANP – Cryo EM
    
  • 6mlq – hKIFL 7 MD + Tubulin + GTP + GDP + ADP – Cryo EM
    
  • 7rx0 – hKIFL 7 MD + GLI2 ANTubulin + GTP + GDP + G2P – Cryo EM
    
• KIF-like 9 or kinesin-9
  • 3nwn – hKIFL 9+ADP
    
• KIF-like 10A or kinesin-6
  • 3j2u – hKIFL 10A head domain – Cryo EM
    
  • 6b0c, 6b0l – DmKIFL 10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM
    
  • 6vpp – DmKIFL 61F + tubulin + GTP + GDP + Mg – Cryo EM
    
  • 6vpo – DmKIFL 61F + tubulin + GTP + GDP + ANP + Mg – Cryo EM
    
  • 6b0i – DmKIFL 10A + tubulin + GTP + GDP + Mg – Cryo EM
    
• KIF-like 11 or kinesin-5 or Eg5
  • 4b7b – hKIFL 11 (mutant) + ADP + Co + Cd
    
  • 3ken, 2wog, 2x2r, 2xae, 4bbg – hKIFL 11 +S-trityl-L-cysteine derivative + ADP + Mg
    
  • 3wpn – hKIFL 11 +inhibitor
    
  • 2uyi, 2uym, 2gm1, 2pg2, 2fme, 2x7d, 2x7c, 2ieh, 3cjo, 2g1q, 2fl2, 2fl6, 1yrs, 2q2y, 2fky, 2q2z, 3k3b, 2x7e, 4a50, 4a51, 3zcw, 6g6y, **6g6z, 6hkx, 6hky - hKIF11+inhibitor +ADP + Mg
    
  • 4bxn, 4as7 – hKIFL 11+inhibitor +ADP + Cd
    
  • 3l9h – hKIFL 11+inhibitor +ADP
    
  • 4zhi – hKIFL 11 MD +ADP
    
  • 1x88, 1q0b – hKIFL 11 +Mg + ADP+monastrol
    
  • 4ap0, 4a5y – hKIFL 11 +MgADP + ispinesib + Mg
    
  • 3hqd – hKIFL 11 +AMPPNP+Mg
    
  • 1ii6, 4a1z, 4a28 – hKIFL11 +ADP+Mg
    
  • 4zca, 6tle, 6trl, 6y1i – hKIFL 11 (mutant) +ADP+Mg
    
  • 3k5e – hKIFL 11 +ADP+enastrol + Mg
    
  • 4aqv, 4aqw – hKIFL 11 (mutant) + tubulin + GDP + GTP + Mg – Cryo EM
    
  • 4ck5, 4ck6, 4ck7 – hKIFL 11 (mutant) + tubulin + ADP + GDP + GTP + Mg – Cryo EM
    
  • 6ta3, 6tiw – hKIFL 11 MD (mutant) + tubulin + G2P + quinolin derivative + Mg – Cryo EM
    
  • 6ta4 – hKIFL 11 MD + tubulin + G2P + ANP + Mg – Cryo EM
    
  • 5m5i, 5m5l, 5m5m, 5m5n, 5m5o – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM
    
  • 6s8m – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP – Cryo EM
    
• KIF11
  • 5mm4, 5mm7 – UmKIF + tubulin + GDP + GTP + ANP + taxol – Ustilago maydis – Cryo EM
    
  • 7nb8 – PfKIF MD + tubulin + GTP + G2P – Plasmodium falciparum – Cryo EM
    
  • 7nba – PfKIF MD + tubulin + GTP + G2P + ANP – Cryo EM
    
• KIF13A, KIF13B or kinesin-3
  • 3gbj – hKIF13B MD+ADP
    
  • 5b64 – mKIF13B MBS domain + MAGUK
    
  • 3kin, 2kin – rKIF MD
    
  • 6a1z – rKIF13B
    
  • 5zbs, 6a20, 7d8v – rKIF13B (mutant)
    
  • 7d8v – rKIF13B (mutant) + ADP
    
  • 5zbr – rKIF13B MD + AMPPNP
    
• KIF-like 13B
  • 2cow – hKIFL 13B CAP-gly domain – NMR
    
  • 3fm8 – hKIFL 13B FHA domain + centaurin-alpha-1
    
  • 5djo – mKIFL 13A CC1-FHA domain
    
  • 5djn – mKIFL 13A coiled-coil domain (mutant)
    
• KIF-like 14 or kinesin-3
  • 6wwe, 6wwi, 6wwt – hKIF14L MD + Tubulin + GTP + GDP – Cryo EM
    
  • 6wwf, 6wwh, 6wwg, 6wwj, 6wwk, 6wwl, 6wwm, 6wwn, 6wwo, 6wwp, 6wwq, 6wwr, 6wws, 6wwu, 6wwv, 7lvq, 7lvr – mKIF14L MD + Tubulin + nucleotides – Cryo EM
    
• KIF-like Kar3
  • 1f9t, 1f9u, 1f9v, 1f9w, 3kar – yKIFL Kar3 MD (mutant) – yeast
    
  • 4etp – yKIFL Kar3 MD (mutant) + VIK1
    
• KIF-like 15 or kinesin-12
  • 4bn2 – hKIFL 15 MD
    
  • 7ryp – hKIFL 15 MD + KIF-binding protein – Cryo EM
    
  • 6zpi – hKIFL 15 MD + tubulin + GDP + GTP + Mg – Cryo EM
    
• KIF-like 16B or kinesin-3
  • 2v14, 6ee0 – hKIFL 16B PX homology domain 1179-1312
    
• KIF-like 18A or kinesin-8
  • 3lre – hKIFL 18A MD
    
  • 5oam – hKIFL 18A MD + tubulin + GTP
    
  • 5ocu – hKIFL 18A MD + tubulin + GTP + GDP + ANP
    
  • 5ogc – hKIFL 18A MD + tubulin + GTP + GDP + taxol
    
  • 7rsi – hKIFL 18A MD + KIF-binding protein + ADP – Cryo EM
    
• KIF-like 19A or kinesin-8
  • 5gsy – mKIFL 19A MD + GDP
    
  • 5gsz – mKIFL 19A MD + ADP
    
• KIF-like 20A or kinesin-6
  • 6yip – hKIFL 20A coiled coil domain 596-668
    
  • 5nd3 – mKIFL 20A MD + tubulin
    
  • 5nd2, 5nd4 – mKIFL 20A MD + tubulin + ADP
    
  • 5nd7 – mKIFL 20A MD + tubulin + AMPPNP
    
  • 5lef – mKIFL 20A residues 603-665 + RAB-6
    
  • 5x3e - KIFL MD - Caenorhabditis elegans
    
• KIF-like 21A or kinesin-4
  • 5d3a – hKIFL 21A coiled coil domain 938-1017
    
  • 7klj – hKIFL 21A WD-repeat domain 1324-1640
    
• KIF-like 22 or kinesin-10
  • 2edu – hKIFL 22 C-terminal – NMR
    
  • 6nje – hKIFL 22 MD +ADP
    
• KIF23 or kinesin-6
  • 3vhx – hKIFL 23 794-911 + ADP-ribosylation factor 6
    
  • 2ncd, 1cz7 – DmKIF MD non-claret disjuctional (NCD) dimer
    
  • 3l1c – DmNCD (mutant)
    
  • 1ry6 – PfKIF MD
    
  • 7nba – PfKlF + tubulin + GTP + G2P + ANP + Mg – Cryo EM
    
  • 7nb8 – PfKlF + tubulin + GTP + G2P + Mg – Cryo EM
    
  • 1goj – NcKIF MD
    
• Kinesin light chain (KLC)
  • 5oj8, 7ai4, 7aie – hKLC1 TPR domain
    
  • 6fuz – hKLC1 TPR domain + nanobody
    
  • 3edt – hKLC2
    
  • 3ceq, 3nf1 – hKLC2 TPR domain
    
  • 6f9i – hKLC2 + clcytenin peptide
    
  • 6fv0 – mKLC1 TPR domain + nanobody
    
  • 5ojf – mKLC2 TPR domain
    
  • 3zfw, 5fjy, 6ejn, 6swu - mKLC2 TPR domain + peptide
    

• NOD
  • 3dc4 – DmNOD catalytic core domain+ADP + Mg
    
  • 3dcb - DmNOD catalytic core domain+AMPPNP + Mg
    
  • 3dco - DmNOD catalytic core domain+ cTubulin + ADP + GDP + GTP + Mg
    
  • 3pxn - DmNOD catalytic core domain+ADP + Mn