7ryp

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Cryo-EM structure of KIFBP:KIF15Cryo-EM structure of KIFBP:KIF15

Structural highlights

7ryp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 4.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KIF15_HUMAN Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly (By similarity).

Publication Abstract from PubMed

[Figure: see text].

Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding.,Solon AL, Tan Z, Schutt KL, Jepsen L, Haynes SE, Nesvizhskii AI, Sept D, Stumpff J, Ohi R, Cianfrocco MA Sci Adv. 2021 Nov 19;7(47):eabj9812. doi: 10.1126/sciadv.abj9812. Epub 2021 Nov, 19. PMID:34797717[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Solon AL, Tan Z, Schutt KL, Jepsen L, Haynes SE, Nesvizhskii AI, Sept D, Stumpff J, Ohi R, Cianfrocco MA. Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding. Sci Adv. 2021 Nov 19;7(47):eabj9812. doi: 10.1126/sciadv.abj9812. Epub 2021 Nov, 19. PMID:34797717 doi:http://dx.doi.org/10.1126/sciadv.abj9812

7ryp, resolution 4.80Å

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OCA