6s8m
S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP stateS. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state
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Structural highlights
FunctionCUT7_SCHPO Could be a spindle pole body motor. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules which interdigitate to form a short spindle that elongates to span the nucleus at metaphase. Mutations at cut7 block spindle formation. See AlsoContents |