Actin 3D structures

3D Structures of Actin3D Structures of Actin

Updated on 08-September-2024

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• α actin 1 (Aa)
  • 3hbt, 2zwh, 1nwk, 1j6z, 3g37, 2y83 – rAa – rabbit
    
  • 2q1n, 2q31, 2a5x, 1rdw, 1rfq, 1lcu – rAa – dimer
    
  • 2hmp – rAa – protease cleaved
    
  • 2zwh, 2gwj, 2gwk – rAa-ATP
    
  • 3b5u – rAa filament – fiber diffraction
    
• α actin 1 complex with gelsolin
  • 2ff3 - rAa+ hGelsolin +domains of hWASP
    
  • 1eqy, 3cjb, 1p8z, 3ffk, 3tu5, 4pkg, 4pkh, 4pki, 7whg – rAa+hGelsolin
    
  • 1rgi - rAa+hoGelsolin – horse (ho)
    
  • 1t44 - rAa+hGelsolin/mThymosin β-4
    
  • 4z94 - rAa+hGelsolin/tropomodulin/leiomodin
    
  • 2ff6 - rAa+DmCiboulot+hGelsolin
    
  • 7c2f, 7c2g, 7c2h, 7whf - rAa+ Gelsolin
    
  • 1mdu – cAa+hGelsolin - chicken
    
  • 4cbu, 5mvv – PfAa + gelsolin – Plasmodium falciparum
    
  • 4cbw – PbAa + gelsolin – Plasmodium berghei
    
• F-actin (α actin 1 complex with ADP)
  • 9b3r – hFAa – Cryo EM
    
  • 9b3q – hFAa (mutant) – Cryo EM
    
  • 8dmy – bFAa - Cryo EM
    
  • 3mfp, 4a7n, 3jbj, 6bnu, 3j8i, 3j8j, 3j8k, 6bno, 6avb, 6av9, 5mvy, 5mva, 6fhl, 5oof, 5ooe, 5ood, 5ooc, 5onv, 7uxf, 6t23, 6t24, 6vau, 8a2r, 8a2s, 8a2t, 8a2u, 8a2y, 8a2z, 8dmx, 8f8p, 8f8q, 8f8r, 8f8s, 8ru0, 8uz0, 8uz1 – rFAa – Cryo EM
    
  • 6kll, 6kln – mFAa – mouse - Cryo EM
    
  • 6djn, 6djo, 7bt7, 7k20, 7k21, 7r8v, 8d13, 8d14, 8d15, 8d16, 8d17 – cFAa - Cryo EM
    
  • 8ord – FAa – zebrafish - Cryo EM
    
  • 6iug – FAa – maize - Cryo EM
    
  • 8thx, 8ti3 – yFAa – yeast - Cryo EM
    
  • 8thy – yFAa (mutant) - Cryo EM
    
  • 7q8b, 7q8c - LmFAa – Leishmania major - Cryo EM
    
  • 8trm – FAa – Toxoplasma gondii
    
• α actin 1 complex with small molecule
  • 2q36, 1qz5 – rAa+kabiramide C + ATP
    
  • 2vyp – rAa+myxobacterial rhizopodin + ATP
    
  • 1ijj - rAa+latrunculin A
    
  • 2fxu – rAa+bistramide A
    
  • 1wua – rAa+alpyronine A
    
  • 4k41, 1qz6, 1s22, 4k42, 4k43, 2asm, 2asp, 2aso, 1yxq, 1s22, 3m6g, 6mgo - rAa+ macrolide
    
  • 1qz6 – rAa+jaspisamide derivative
    
  • 7ahn, 7ahq – rFAa+jaspisamide derivative
    
  • 6qri – rAa+ chivosazole
    
  • 7z7i – rFAa + ADP-ribose – Cryo EM
    
  • 7pm3 – rFAa + JASP – Cryo EM
    
  • 6djm – cAa + AMPPNP - Cryo EM
    
  • 7k20, 7k21 – cFAa + pyrene - Cryo EM
    
  • 5ogw – PfFAa + JASP – Cryo EM
    
  • 6bqw – Aa + AMPPNP – Bacillus subtilis - Cryo EM
    
  • 8trn – TgFAa + JASP – Cryo EM
    
• α actin 1 binary complex with protein
  • 6fm2 – hAa + adenylyl cyclase-associated protein
    
  • 7lrg - pAa + MYBP-C – Cryo EM
    
  • 3j8a - mAa + tropomyosin - mouse
    
  • 8q4g - mAa + tropomyosin – Cryo EM
    
  • 6bnw, 6bnp, 6bih - rAa + myosin – Cryo EM
    
  • 8c4c - rFAa + SIPA – Cryo EM
    
  • 8pvx - rFAa + LIFEACT13 – Cryo EM
    
  • 8rv2, 9az4, 9b03, 9b0k - rFAa + inverted formin – Cryo EM
    
  • 2v51, 2v52, 2yje, 2yjf – rAa+mMKL/Myocardin-like protein
    
  • 2vcp – rAa+ neural wiskott-aldrich syndrome protein (hWASP) – human (h)
    
  • 2a3z, 2a40, 2a41 – rAa+bDNase I+domains of hWASP – bovine
    
  • 2a42 – rAa+cDNase I
    
  • 6wvt, 7utj – rFAa+ catenin – Cryo EM
    
  • 4eah – rAa + formin-like protein 3 FH2 domain
    
  • 3daw – rAa+mTwinfilin-1
    
  • 3buz – rAa+Iota toxin component IA
    
  • 4b1u, 4b1v, 4b1w, 4b1x, 4b1y, 4b1z – rAa + phosphatase and actin regulator
    
  • 4pl8 - rAa+ Thymosin β-4
    
  • 3u8x - rAa+DmThymosin β-4 - Drosophila melanogaster
    
  • 2pbd, 5zzb, 5zza, 5yee – rAa+hProfilin-1
    
  • 2q97 – rAa+toxofilin
    
  • 2q0r – rAa+pectenotoxin-2
    
  • 1y64 – rAa+yBNI1 domain FH2
    
  • 1sqk – rAa+DmCiboulot
    
  • 3sjh, 3u9d, 3u9z - rAa+DmCiboulot thymosin β-4 domain
    
  • 3mn5 – rAa+ DmSpire WH2 domain
    
  • 1lot, 1kxp, 1ma9 – rAa+hVitamin D binding protein
    
  • 3m1f – rAa+VOPL WH2 domain
    
  • 3m3n – rAa+mN-WASP
    
  • 3tpq – rAa + MAL RPEL domain
    
  • 3ue5 – rAa + spire domain D
    
  • 4gy2 – rAa + ι toxin component IA
    
  • 3jbi – rAa + vinculin - CryoEM
    
  • 4wyb – rAa + BUD6
    
  • 5ypu – rAa + protein cordon-bleu WH2 domain
    
  • 6jbk, 6jcu, 6jh8, 6jh9 – rAa + protein cordon-bleu peptide
    
  • 6gvc – rAa + Rho GTPase-activating protein
    
  • 7kch, 7r91, 7rb8, 7rb9, 8syf - cAa + myosin – Cryo EM
    
  • 3j4k - cAa + tropomyosin
    
  • 5yu8 – cAa + cofilin 2
    
  • 7w52 – cAa + fragmin + ATP
    
  • 7w4z – cAa + fragmin + AMPPNP
    
  • 5ce3, 4ci6 – Aa + protein kinase YopO – fall armyworm
    
  • 6i4d – PfAa + mGelsolin
    
• F-actin complex with protein
  • 7w50, 7w51, 8gsu – hFAa + in
    
  • 8gt1, 8gt3, 8gt5 – hFAa (mutant) + fragmin
    
  • 8ru2 - hFAa + mDia1 – Cryo EM
    
  • 7ztc, 7ztd – hFAa + tropomyosin alpha-1 - Cryo EM
    
  • 5nol, 5noj, 5nog – pFAa + tropomyosin alpha-1 – pig - Cryo EM
    
  • 8f8t - rFAa + tropomodulin – Cryo EM
    
  • 6vec – rFAa + LCP1 – Cryo EM
    
  • 3jbk – rFAa + metavinculin - CryoEM
    
  • 6t1y, 6t20, 6t25, 6u96 – rFAa + phalloidin - CryoEM
    
  • 6uby, 6uc0, 6uc4, 6vao – rFAa + cofilin 1 – Cryo EM
    
  • 9b27, 9b3d - rFAa + mDia1 – Cryo EM
    
  • 7uuw - rFAa + catenin-like – Cryo EM
    
  • 7bti - cFAa + phalloidin – Cryo EM
    
  • 8c4e - cFAa + SIPA – Cryo EM
    
  • 7yne - cFAa + fragmin
    
• α actin 1 higher complex with protein
  • 8gsw, 8gt2, 8gt4 – hAa (mutant) + fragmin + AMPPNP
    
  • 8rty – hFAa + Cdc12 + profilin - Cryo EM
    
  • 8rtt – hFAa + Cdc12 + phalloidin - Cryo EM
    
  • 8efh, 8efi – hFAa + tropomyosin alpha-1 + myosin – Cryo EM
    
  • 9c57, 9c62, 9c6n – hFAa in TIP60 complex + ATP – Cryo EM
    
  • 8xvg, 8xvt – hFAa in NUA4/TIP60 complex + ATP – Cryo EM
    
  • 7zi4 – hAa in INO80 complex + nucleosome – Cryo EM
    
  • 8dd0 – pAa + troponin T2 + tropomyosin alpha-1 - Cryo EM
    
  • 8uww, 8uwx, 8uwy, 8uyd, 8uz5, 8uz6, 8uzx, 8uzy, 8v01, 8v0i, 8v0k, 8v0y – pAa + troponin I,C,T2 + tropomyosin alpha-1 - Cryo EM
    
  • 8ib2 – pFAb + spectrin – Cryo EM
    
  • 7tit, 7tj7 - pAa + MYBP-C + tropomyosin – Cryo EM
    
  • 8enc – pFAa + tropomyosin alpha-1 + myosin – Cryo EM
    
  • 7jh7 – pAa in actomyosin complex – Cryo EM
    
  • 7ko4, 7ko5, 7ko7, 7kon, 7kor – pAa in thin filament – Cryo EM
    
  • 5jlf, 3j8a – rFAa + tropomyosin alpha-1 – Cryo EM
    
  • 6kn7, 6kn8 – rAa in thin filament – Cryo EM
    
  • 6c1h, 6c1g, 6c1d - rAa + myosin + calmodulin
    
  • 6bnv - rAa + myosin + calmodulin – Cryo EM
    
  • 6bnq, 6blh - rFAa + myosin – Cryo EM
    
  • 6yp9 – rAa+mTwinfilin-1 + ATP
    
  • 6rsw, 7ccc – rFAa + mTwinfilin-1 + CAP-1
    
  • 1esv - rAa+hGelsolin+ latrunculin A
    
  • 3cjc - rAa+hGelsolin+cDNase I
    
  • 2d1k - rAa+hWH2 domain of MIN+cDNase I
    
  • 7nxv – rAa + bDNase I + protein phosphatase
    
  • 6nas, 6nbe, 6nbw – rAa + hProfilin-1 + acetyltransferase + acetyl CoA + ATP
    
  • 9azp – rFAa + hProfilin-1 + formin + ATP – Cryo EM
    
  • 2pav - rAa+hProfilin-1+hVASP
    
  • 8bjh, 8bji, 8bjj - rAa+hProfilin-1+ adenylyl cyclase
    
  • 2q0u - rAa+pectenotoxin-2+latrunculin B
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  • 7ad9 – rFAa + phalloidin + lifeact - CryoEM
    
  • 7p1g – rFAa + phalloidin + ExoY - CryoEM
    
  • 7tpt – rAa in ARP2/3 complex – Cryo EM
    
  • 4a7f, 4a7h, 4a7l, 5h53, 5kg8 7ply, 7plz, 7pm0, 7pm1, 7pm2, 7plt, 7plu, 7plv, 7plw, 7plx, 7pm5, 7pm6, 7pm7, 7pm8, 7pm9, 7pma, 7pmb, 7pmc, 7pmd, 7pme, 7pmf, 7pmg, 7pmh, 7pmi, 7pmj, 7pml – rAa in actomyosin complex – Cryo EM
    
  • 4v0u – rAa + protein phosphatase 1 +serine/threonine protein phosphatase
    
  • 4h0t – rAa + ι toxin component IA + ADPR
    
  • 4h03, 4h0v, 4h0x, 4h0y – rAa + ι toxin component IA + NAD
    
  • 7z7h – rFAa + TccC3 + ADP-ribose – Cryo EM
    
  • 8jo3 – rFAa + substrate of the DOT/ICM + AMP – Cryo EM
    
  • 8jo4 – rFAa + substrate of the DOT/ICM + ATP – Cryo EM
    
  • 7nep, 7qin – mAa in actomyosin complex – Cryo EM
    
  • 7aqk – mAa in ARP2/3 complex – Cryo EM
    
  • 6x5z - cAa + tropomyosin + myosin – Cryo EM
    
  • 6d8c - cAa + filamin + phalloidin – Cryo EM
    
  • 7r94, 7sx8, 7sx9, 7sxa - cFAa + plastin-3 – Cryo EM
    
  • 6m5g - cFAa + utrophin – Cryo EM
    
  • 7bte - cFAa + lifeact – Cryo EM
    
  • 2w49 – cAa + troponin I,C,T2 + tropomyosin alpha-1 - Cryo EM
    
  • 7w52 – cAa + fragmin + ATP
    
  • 6upw – cFAa + metavinculin - CryoEM
    
  • 6upv – cFAa + catenin – Cryo EM
    
  • 7udt, 7udu - cFAa + myosin + regulatory light chain – Cryo EM
    
  • 5i9e – yAa + actin-related protein 4 + helicase
    
  • 7yfn, 7yfp, 8esc – yAa in NUA4 complex + ATP – Cryo EM
    
  • 8a5a, 8a5o, 8ets, 8etu, 8etw – yAa in INO80 complex – Cryo EM
    
  • 8eu9, 8euf – yAa in INO80 complex + nucleosome – Cryo EM
    
  • 8oo7, 8oof, 8oop, 8oor, 8oot – CtAa in INO80 complex – Chaetomium thermophilum - Cryo EM
    
  • 8a5d, 8a5p, 8a5q – CtAa in INO80 complex + DNA - Cryo EM
    
  • 6i4e, 6i4m – PfFAa + mGelsolin
    
  • 6i4i, 6i4j – PfFAa (mutant) + mGelsolin
    
  • 6i4f, 6i4l – PfAa (mutant) + mGelsolin + ATP + ADP
    
  • 6i4g, 6i4h, 6i4k – PfAa (mutant) + mGelsolin + ATP
    
  • 6tu7 - PfFAa + myosin – Cryo EM
    
  • 7q8s - LmFAa + cofilin - Cryo EM
    
  • 8c47 - LmFAa + profilin + ATP - Cryo EM
    
• Beta actin (Ab)
  • 8cog – hAb – Cryo EM
    
  • 3lue – hAb+hAlpha-actinin
    
  • 3byh – hAb+hFimbrin ABD2 – Cryo EM
    
  • 3j82 – hAb + DNGR-1 - CryoEM
    
  • 6anu – hAb + spectrin – Cryo EM
    
  • 7p1h – hAb (mutant) + profilin + MMBP – Cryo EM
    
  • 8oid – hAb (mutant) + ADP – Cryo EM
    
  • 8vrd, 8vrk – hAb in gamma tubulin ring complex - CryoEM
    
  • 6znl – pAb in dynactin complex – Cryo EM
    
  • 7z8m – pAb in dynactin complex + BICDR1 – Cryo EM
    
  • 3u4l, 3ub5 – bAb + profilin-1 - bovine
    
  • 8oi8 – bAb (mutant) – Cryo EM
    
  • 8oi6 – bAb + phalloidin – Cryo EM
    
  • 7pdz – bAb + phalloidin + F-actin-capping protein – Cryo EM
    
  • 8iah, 8iai – pAb in spectrin complex – Cryo EM
    
  • 7u8k – rAb + cofilin 2 - NMR
    
  • 2oan – cAb
    
  • 3j0s – cAb + cofilin 2
    
  • 4cbx – PbAb + gelsolin
    
• Gamma 1 actin (Ag)
  • 8dnf, 8dnh, 8v2o – hAb - CryoEM
    
  • 8v2z, 8v30 – hAb (mutant) - CryoEM
    
  • 1h1v – hAg+rGelsolin
    
  • 5jlh, 6g2t, 6cxj, 6cxi – hAg + myosin-14 + tropomyosin alpha-3 – Cryo-EM
    
  • 1atn – rAg+cDNase I
    
  • 8j9b – rAg+ type IV secretion protein
    
  • 1hlu, 2btf – cAg+cProfilin
    
  • 1o1g, 1o1a, 1o1b, 1o1c, 1o1d, 1o1e, 1o1f, 1o18, 1o19, 1mvw, 1m8q –cAg+cMyosin II - tomography
    
  • 3w3d – cAg + DNase I
    
  • 3chw – Major DdAg+hProfilin+poly-Pro repeat – Dictyostelium discoideum
    
  • 3ci5, 3cip, 1nmd - Major DdAg+hGelsolin
    
  • 3a5l, 3a5m, 3a5n, 3a5o - Major DdAg+hGelsolin (mutant)
    
  • 1c0g, 1dej – DdAg:tetrahymenatA+hGelsolin
    
  • 1nm1 - DdAg+hGelsolin+Mg-ATP
    
  • 1nlv, 1c0f – DdAg+hGelsolin
    
  • 1yvn – yA (mutant)+hGelsolin
    
  • 1yag - yA+hGelsolin
    
  • 1d4x – Ag 1/3+hGelsolin – C. elegans
    
  • 3b63 – actin filament – Limulus polyphemus
    
• Actin 2
  • 8d18 – cFA2 – Cryo EM
    
  • 8ccn, 8cco – PfFA2 – Cryo EM
    
• Actin 5C (A5C)
  • 4rwt, 5wfn – DmA5C + leiomodin
    
  • 3eks – DmAg 5c (mutant)
    
  • 3eku – DmAg 5c (mutant)+cytochalasin D
    
  • 3el2, 2hf4 - DmAg 5c (mutant)+Ca-ATP
    
  • 2hf3 - DmAg 5c (mutant)+Ca-ADP
    
  • 3mmv – DmA-5C+spire WH2 domain
    
  • 3mn6, 3mn7, 3mn9 - DmA-5C (mutant)+spire
    
  • 4jhd – DmAg 5c + protein cordon-bleu WH2 domain
    
  • 8oh4 – DmAg 5c (mutant) + twinstar – Cryo EM
    
  • 4efh – A + spire domains C,D – Acanthamoeba castellanii