3D structures of Ubiquitin activating enzyme

3D Structures of ubiquitin activating enzyme3D Structures of ubiquitin activating enzyme

Updated on 22-February-2024 - For a general description of the protein see Ubiquitin activating enzyme

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• Ubiquitin activating enzyme E1
  • 4p22 – hUba N-terminal (mutant) - human
    
  • 4ii2 – hUba + E2 Ubc4 + ubiquitin-ribosomal protein L40 + ATP
    
  • 4ii3 – hUba + ubiquitin-ribosomal protein L40 + ATP
    
  • 6dc6 – hUba (mutant) + ubiquitin
    
  • 6nya – hUba1 + Ubc3 + ubiquitin
    
  • 1z7l – mUba 1 second catalytic Cys half-domain - mouse
    
  • 2v31 – mUba X first catalytic Cys half-domain
    
  • 2lzj – mUba X first catalytic Cys half-domain - NMR
    
  • 5um6 – fyUba1 – fission yeast
    
  • 6o83, 6o82 – fyUba + ubiquitin-ribosomal protein L40 + adenosine derivative
    
  • 5um6 – yUba (mutant) – yeast
    
  • 3cmm, 4nnj – yUba + ubiquitin + AMP
    
  • 5tr4 – yUba (mutant) + ubiquitin
    
  • 7zh9 – yUba + ATP
    
  • 6zqh – yUba + ubiquitin-ribosomal protein S31
    
  • 6zqh – yUba + ubiquitin-ribosomal protein S31
    
  • 5l6h, 5l6i, 5l6j – yUba + ubiquitin-ribosomal protein S31 + inhibitor
    
  • 6zhs, 6zht – yUba + E2
    
  • 5knl, 6nya, 7k5j – yUba + ubiquitin + E2
    
  • 6zhu – yUba + ATP + E2
    
• Ubiquitin activating enzyme E1-like
  • 3ong, 3onh – yUba + SUMO-conjugating enzyme Ubc9
    
• Ubiquitin activating enzyme E1C or NEDD8-activating enzyme ubiquitin activating enzyme 3 subunit
  • 2lq7 – hUba catlytic subunit - NMR
    
  • 1r4m – hUba + NEDD8
    
  • 1r4n – hUba (mutant) + NEDD8 + APPBP1 + ATP
    
  • 1tt5 – hUba + E2 Ubc12 + APPBP1
    
  • 1y8x – hUba + E2 Ubc12
    
  • 1yov – hUba + APPBP1
    
  • 3dbr – hUba + APPBP1 (mutant) + NEDD8
    
  • 2nvu – hUba + E2 Ubc12 + APPBP1 + NEDD8 + ATP
    
  • 3gzn – hUba + inhibitor + APPBP1 + NEDD8 + ATP
    
  • 3dbh, 3dbl – hUba (mutant) + NEDD8
    
  • 3fn1 – hUba (mutant) + NEDD8-conjugating enzyme
    
• Uba4 or adenyltransferase and sulfurtransferase Uba4
  • 6yub – CtUba – Chaetonium thermophilum
    
  • 6yuc – CtUba + Urm1
    
• Ubiquitin activating enzyme 5 or Ubiquitin-like modifier-activating enzyme 5
  • 5ia8 – hUba residues 1-83
    
  • 3guc – hUba + AMPPNP
    
  • 3h8v, 6h78, 7pvn – hUba + ATP
    
  • 5iaa – hUba + UFM1
    
  • 5l95 – hUba + UFM1 + AMP
    
  • 6h77 – hUba + UFM1 + ATP
    
  • 6h8c – hUba LIR motif + GABARAPL2 - NMR
    
• Uba6 or Ubiquitin-like modifier-activating enzyme 6
  • 7pyv – hUba + UbD
    
  • 7sol – hUba (mutant) + Ub
    
• Uba7 or Ubiquitin-like modifier-activating enzyme 7
  • 8oif, 8se9, 8sea, 8seb, 8sv8 – hUba + Ub-like protein + Ub/ISG15-conjugating enzyme E2 L6 – Cryo EM
    
• Ubiquitin-like 1 activating enzyme E1A or SUMO-1 activating enzyme subunit 1
  • 1y8r – hSAE subunit 1 + hSAE subunit 2 + SMTC3
    
• Ubiquitin-like modifier-activating enzyme 2 or SUMO-activating enzyme subunit 2
  • 6cwz – hSAE subunits 1,2
    
  • 1y8q – hSAE subunits 1,2 + ATP
    
  • 6cwy – hSAE subunits 1,2 + inhibitor
    
  • 3kyc – hSAE subunits 1,2 + SUMO
    
  • 3kyd – hSAE subunits 1,2 + SUMO + AMP
    
  • 5fq2, 4w5v – hSAE ubiquitin domain + Ubc9
    
• Ubiquitin-like modifier-activating enzyme Atg7 see Autophagy-related protein