Protein G

Protein G or immunoglobulin-binding protein G (ProG) is a cell surface protein from Streptococcal bacteria which binds Fab and Fc regions of immunoglobulins. For ProG immunoglobulin-binding domain see Chameleon peptide.

spinqualitylabelsall models Protein G domain II (grey) complex with mouse Fab heavy chain (red) and light chain (aqua) (PDB code 1uwx). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of protein G3D Structures of protein G

Updated on 03-February-2022

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• Streptococcus Protein G residues 2-68
  • 6u8c – StProG + antibody – Streptococcus
    
• Streptococcus Protein G residues 56-118
  • 1uwx – StProG + Igg1 Fab
    
  • 1qkz – StProG (mutant) + Igg1 Fab + peptide antigen
    
• Streptococcus Protein G residues 189-244
  • 1em7 – StProG (mutant)
    
• Streptococcus Protein G B1 domain residues 228-282
  • 1pga, 1pgb, 2ju6, 2rmm, 2rpv, 1mpe, 1q10, 2j52, 2j53, 2k0p, 3mp9, 1gb1, 2gi9 - StProG
    
  • 2gb1, 3gb1, 5ub0, 5ubs, 5uce,2n9k, 5ucf, 2n9l, 2plp, 6che, 1qmt, 2lgi, 2nmq, 2rpv - StProG - NMR
    
  • 1mvk, 1fcl, 1fd6, 1em7, 3v3x, 6c9o, 6kmc, 6nla, 6nlb, 6nl9, 6nl8, 6nl7, 6nl6, 5ofs, 6cne, 6cpz, 4wh4, 6l9b, 6lji, 5bmi, 5bmh, 6l91, 6l9d, 5hg2, 5hfy, 5hi1 – StProG (mutant)
    
  • 1q10, 2rmm, 2k0p, 2ju6 – StProG (mutant) – NMR
    
  • 1mi0, 1mhx – ProG (mutant) – Finegoldia magna
    
• Streptococcus Protein G albumin-binding domain residues 254-299
  • 1gjs, 1gjt - StProG albumin-binding domain - NMR
    
• Streptococcus Protein G 3rd Igg-binding domain residues 300-357
  • 3fil, 1pgx, 2igd, 1igd - StProG
    
  • 3v3x, 5bmg, 6c9o, 6cte, 6nl6, 6nl7, 6nl8, 6nl9, 6nlb – StProG (mutant)
    
  • 2plp, 1p7f, 1p7e, 2n7j, 2lum - StProG - NMR
    
  • 2jsv, 2kq4, 2kwd, 1fcl, 1fd6 - StProG (mutant) - NMR
    
  • 1igc – StProG + Igg1 Fab
    
  • 6o41 – StProG + antibody
    
• Streptococcus Protein G domains II+III residues 367-430
  • 2on8, 2igg - StProG
    
  • 2igh – StProG – NMR
    
  • 2onq, 2on8 – StProG (mutant)
    
  • 1gb4, 6njf – StProG (mutant) – NMR
    
  • 1fcc – StProG + Igg1 Fc
    
• Streptococcus Protein G residues 443-497
  • 1p7e, 1p7f, 2lum, 2oed - StProG - NMR
    
  • 1zxh - StProG (mutant) - NMR
    
  • 6oc7 – StProG + antibody
    
  • 6wfw – StProG + antibody + peptide
    
• Protein G
  • 1gb1, 2gb1, 2igg, 2igh - SgProG immunoglobulin-binding domain – Streptomyces griseus – NMR
    
  • 2igg, 2igh - SgProG immunoglobulin-binding domains II+III – NMR
    
  • 2gi9, 2qmt – SaProG domain B1 (mutant) – Staphylococcus aureus
    
  • 2klk - SaProG immunoglobulin-binding domain - NMR