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Signal recognition particle receptor

. Water molecules are shown as red spheres.

.

Receptor for activated C kinase 1

Nuclear receptors

The

The .

(PDB entry 1dkf).

The Ligand binding domain for each piece of the dimer has a nearly identical structure of an . These alpha helices form a total of 12 domains per protein (referred to as H1-12), with an additional 2 beta sheets as well. Additionally, the α-helical sandwich formed has been shown to bind All-Trans Retinoic Acid (ATRA), the isomer of RA used by the body. Both monomers contain two regions of activity, the and the .

Endoplasmic reticulum/Sarcoplasmic reticulum receptors

Ligand-gated Calcium channels

Inositol 1,4,5-Trisphosphate Receptor

Ryanodine receptor

SEE ALSO:


Human androgen receptor ligand-binding domain complex with modulator (PDB code 3b5r)

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ReferencesReferences

  1. Li MJ, Greenblatt HM, Dym O, Albeck S, Pais A, Gunanathan C, Milstein D, Degani H, Sussman JL. Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators. J Med Chem. 2011 Apr 7. PMID:21473635 doi:10.1021/jm200192y

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Alexander Berchansky