Neuraminidase 3D structures

3D structures of Neuraminidase3D structures of Neuraminidase

Updated on 05-February-2020

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• Influenza virus neuraminidase
  • 3nss, 3k36, 3beq, 3cye, 2cml, 2b8h, 2ht5, 1v0z, 1nn2, 4hzv, 4fvk, 4gez – IvNANA residues 82-469 – Influenza virus
    
  • 4fvk, 4gez - IvNANA residues 76-442
    
  • 3k38, 4hzy – IvNANA (mutant)
    
  • 4b7m, 6d96 - IvNAN H1n1
    
  • 6n4d – IvNAN H3n2
    
  • 4qn4 – IvNAN H3n6
    
  • 4wa3 – IvNAN H3n8
    
  • 5hug, 2ht5, 2htv, 2hty – IvNAN H5n1
    
  • 5huk – IvNAN H5n2
    
  • 5hun, 5hum – IvNAN H5n6
    
  • 5l14, 3nn9, 4nn9, 5nn9, 6nn9, 4mwj, 4mwl – IvNAN H7n9
    
  • 4qn3 – IvNAN H10n7
    
  • 7nn9, 6mcx - IvNAN H11n9 Tern
    
  • 3sal - IvNAN H12n5 residues 82-469
    
  • 4gdi, 4gdj - IvNAN H17n10
    
  • 4mc7 – IvNAN H18n11
    
  • 2hty - IvNAN N1 residues 82-469
    
  • 4gzo, 4k1h, 4k1i, 4k1k - IvNAN N2 residues 77-469
    
  • 4gzs, 4k1j - IvNAN N2 residues 77-469 (mutant)
    
  • 2htv - IvNAN N4 residues 82-469
    
  • 6hgb – IvNAN N6
    
  • 2ht5 – IvNAN N8 residues 82-469
    
  • 2qwa - IvNAN N9 Tern (mutant)
    
• Binary complexes of Influenza virus neuraminidase
  • 3o9j, 3o9k, 2c4a, 2c4l, 1w1x, 1w20, 1w21, 1nsb, 1nsc, 1nsd – IvNANA + sialic derivative
    
  • 3k37, 3b7e, 1vcj, 1l7f, 1f8c, 1f8d, 1f8e, 1a4g, 1a4q, 1b9t, 1b9v, 1b9s, 1inf, 1ing, 1inh, 1ivb, 1ivc, 1ivd, 1ive, 1ivf, 1ivg, 4d8s, 4ks1, 4ks2, 4ks3, 4ks4, 4ks5, 4m3m, 4mju, 4mjv – IvNANA + inhibitor
    
  • 3k39, 3k3a, 3ckz, 3cl0, 3cl2, 1l7g, 1l7h - IvNANA (mutant) + inhibitor
    
  • 1f8b, 1inv, 1inw, 1inx, 1iny, 4gb1 – IvNANA + sialic acid analog
    
  • 3ti3, 3ti4, 3ti5, 3ti6, 6g02, 6g01 - IvNAN H1n1 + inhibitor
    
  • 4qnp, 6q23 - IvNAN H1n1 + antibody
    
  • 3tia, 3tib, 3tic – IvNAN H2n2 + inhibitor
    
  • 6q20 - IvNAN H2n2 + antibody
    
  • 6n6b - IvNAN H3n2 + antibody
    
  • 2bat, 4gzw, 4gzx, 4gzq – IvNAN H3n2 + sialic acid
    
  • 2ht7, 2ht8, 2htq, 2htu – IvNAN H5n1 + inhibitor
    
  • 2htr, 2htw – IvNAN H5n1 + sialic acid analog<br /
  • 5l18 - IvNAN H7n9 + sialic acid
    
  • 6q1z - IvNAN H7n9 + antibody
    
  • 1nna, 1nnb, 5w2y, 5w2w, 5w2u, 5w26 - IvNAN H11n9 + neuraminic acid derivative
    
  • 4dgr - IvNAN H11n9 + benzoic acid derivative
    
  • 4weg - IvNAN H11n9 + sialic acid derivative
    
  • 1bji, 1nnc - IvNAN H11n9 Tern + sialic acid analog
    
  • 1xoe, 1xog, 3w09 - IvNAN H11n9 Tern + inhibitor
    
  • 4qn5 - IvNAN H12n5 + sialic acid
    
  • 4h52, 4h53 – IvNAN N2 + inhibitor
    
  • 2qwb - IvNAN N9 Tern (mutant) + sialic derivative
    
  • 2qwc, 2qwd, 2qwe - IvNAN N9 Tern (mutant) + sialic acid analog
    
  • 1mwe - IvNAN N9 Tern + sialic acid
    
  • 2qwf, 2qwg, 2qwh, 2qwi, 2qwj, 2qwk - IvNAN N9 Tern (mutant) + inhibitor
    
  • 1nma, 1nmb, 1a14, 1nca, 1ncb, 1ncc, 1ncd, 2aep, 2aeq, 1nmc - IvNAN N9 Tern + antibody – mouse
    
• Binary complexes of Influenza virus neuraminidase with drugs
  • 4b7j, 4b7n, 4b7q, 4b7r, 5nzn, 6hp0 - IvNAN H1n1 + drug
    
  • 5nzf, 5nze, 5nz4, 5nwe - IvNAN H1n1 (mutant) + drug
    
  • 4gzp, 4gzt, 6br6, 6br5 - IvNAN H3n2 + drug
    
  • 4qn6 - IvNAN H3n6 + drug
    
  • 4wa5, 4wa4 - IvNAN H3n8 + drug
    
  • 5l15, 5l17, 5jyy, 4mwq, 4mwr, 4mwu, 4mwv, 4mww, 4mwx, 4mwy, 4mx0 - IvNAN H7n9 + drug
    
  • 4mwq, 4mwr, 4mwu, 4mwv, 4mww, 4mwx, 4mwy, 4mx0 - IvNAN H7n9 + flu drug
    
  • 4qn7- IvNAN H10n7 + drug
    
  • 3san, 3ti8 - IvNAN H12N5 + flu drug
    
  • 4hzw, 4hzx - IvNAN N3 + flu drug
    
  • 4hzz, 4i00 - IvNAN N3 (mutant) + flu drug
    
  • 6hg5 - IvNAN N6 + flu drug
    
  • 6hfy - IvNAN N6 + DANA
    
  • 6heb, 6hcx - IvNAN N9 + flu drug
    
  • 6hg0 - IvNAN N9 Tern + NANA
    
• Endo-neuraminidase
  • 3gvf, 3gvk, 3gvj – ENANA (mutant) residues 246-910 – Enterobacteria phage K1F
    
  • 3gvl, 3ju4 – ENANA residues 246-910
    
  • 3gw6 – ENANA residues 790-1064
    
• Pseudaminidase
  • 2w38, 3h6j – PNANA – Pseudomonas aeruginosa
• Trans-sialidase
  • 2sli, 1sli, 3sli – lTS + inhibitor – leech
    
  • 1mr5, 1ms3, 1ms4 - TcTS (mutant) – Trypanosoma cruzi
    
  • 1ms0 - TcTS (mutant) + DANA + lactose
    
  • 1ms1, 1ms8 - TcTS (mutant) + DANA
    
  • 3b69 - TcTS (mutant) + NANA derivative
    
  • 1ms5 - TcTS (mutant) + Na-S-Gal
    
  • 1ms9, 3pjq - TcTS (mutant) + lactose
    
  • 1s0i - TcTS (mutant) + sialyl-lactose
    
  • 1s0j - TcTS (mutant) + MUNANA
    
  • 3opz - TcTS (mutant) + antibody
    
  • 2ah2 - TcTS (mutant) + difluorosialic acid
    
• Anhydrosialidase
  • 4x47, 4x4a - RgSal + neuraminic acid derivative - Ruminococcus gnavus
    
  • 4x49 - RgSal + tamiflu
    
  • 4x6k - RgSal + siastatin