Template:STRUCTURE 3gc6
Cluster of Differentiation 38 (CD38), known also as ADP-ribosyl cyclase 1 (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling.
3D Structures of Cluster of Differentiation 383D Structures of Cluster of Differentiation 38
Updated on 12-March-2015
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- CD38
- 3gc6 – bCD38 - bovine
- 3gh3, 3ghh – bCD38 residues 32-278
- 2eg9 - CD38 enzymatic domain (mutant) – mouse
- 2ef1 - hCD38 enzymatic domain – human
- 1yh3 - hCD38 enzymatic domain (mutant)
- 1zvm - hCD38 (mutant)
- 1isf – hADPRC2 (mutant)
- CD38+ligand
- 3i9m, 3i9n – hCD38 enzymatic domain+ADPR analog
- 3f6y – hCD38 enzymatic domain+Ca++
- 3dzf - hCD38 enzymatic domain+intermediate
- 3dzg - hCD38 enzymatic domain (mutant)+intermediate/nicotinamide complex
- 3dzh - hCD38 enzymatic domain (mutant)+GTP
- 3dzi - hCD38 enzymatic domain (mutant)+intermediate/GTP complex
- 3dzj, 3dzk - hCD38 enzymatic domain (mutant)+NMN complex
- 2pgj, 2pgl - hCD38 enzymatic domain (mutant)+substrate analog
- 2o3t - hCD38 enzymatic domain (mutant)+cGDPR
- 3u4h, 3u4i - hCD38 enzymatic domain (mutant)+cIDPR
- 2o3u - hCD38 enzymatic domain (mutant)+NGD
- 2o3q, 2o3r, 2o3s - hCD38 enzymatic domain (mutant)+cADPR
- 4f45 - hCD38 enzymatic domain (mutant)+ NAADP
- 4f46 - hCD38 enzymatic domain (mutant)+ NAADP + ADPRP
- 4cmh - hCD38 enzymatic domain + antibody
- 2i65 – hCD38+NAD
- 3kou - hCD38+NAD derivative
- 2i67 - hCD38 (mutant)+ADPR
- 2hct - hCD38 enzymatic domain (mutant)+NMN
- 3ofs - hCD38 enzymatic domain (mutant)+ ARA-2 F-ADPR
- 3raj - hCD38 enzymatic domain (mutant)+ FAB
- 3rok, 3rom - hCD38 (mutant) + arabinitol derivative
- 3roq - hCD38 (mutant) + hydrofuran derivative
- 3rop - hCD38 (mutant) + arabinitol derivative + nicotinamide
- 3p5s - bADPRC + arabinitol derivative