1zvm

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Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolaseCrystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase

Structural highlights

1zvm is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CD38_HUMAN Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1zvm, resolution 2.20Å

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OCA