4f45

Crystal structure of human CD38 E226Q mutant in complex with NAADPCrystal structure of human CD38 E226Q mutant in complex with NAADP

Structural highlights 4f45 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CD38_HUMAN Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. See Also Cluster of Differentiation CD38

spinqualitylabelsall models 4f45, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image