Fatty acid-binding protein

Fatty acid-binding protein (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells. Some FABSs are linked to metabolic and inflammatory pathways. Various FABS differ in their tissue expression. IFABP is intestinal; HFABP is heart-type; BFABP is brain-type; LFABP is liver-type; AFABP is adipocyte; LMDABP is from flight muscle; TFABP is from testis; EXFABP is extracellular.

3D structures of fatty acid-binding protein3D structures of fatty acid-binding protein

Updated on 07-March-2013

Intestinal fatty acid-binding protein

1ael, 1a57, 1sa8 - rIFABP – rat – NMR
1t8v - rIFABP (mutant) – NMR
1kzw - hIFABP – human – NMR
1kzx - hIFABP (mutant) – NMR

Intestinal fatty acid-binding protein binary complex

3akm - hIFABP + fatty acid analog
3akn - rIFABP + fatty acid analog
1ure - rIFABP + palmitate – NMR

Heart-type fatty acid-binding protein

1g5w - hHFABP – NMR

Brain-type fatty acid-binding protein

1fdq - hBFABP
1fe3 - hBFABP + oleate

Liver-type fatty acid-binding protein

1p6p - LFABP – toad
1tvq - cLFABP – chicken
1zry - cLFABP - NMR
2f73,-3stn - hLFABP
2py1, 2l67, 2l68 - hLFABP – NMR
2ju3, 2ju7 - rLFABP – NMR
2ft9 – AmLFABP - Ambystoma mexicanum

Liver-type fatty acid-binding protein binary complex

3stk, 3stm - hLFABP + palmitate
2ju8 - rLFABP + oleate – NMR
1tw4 - cLFABP + cholate
2jn3 - cLFABP + chenodeoxycholate
2k62 - cLFABP + bile acid-based Gd chelate
2ftb - AmBFABP + oleate

Adipocyte fatty acid-binding protein

1tou, 2hnx, 3q6l, 3rzy - hAFABP
1tow - hAFABP + carbazole butanoic acid
2nnq, 3fr2, 3fr4, 3fr5 - hAFABP + inhibitor
3p6c - hAFABP + citrate
3p6d, 3p6e - hAFABP + propionate derivative
3p6f - hAFABP + phenyl-butyrate
3p6g, 3p6h - hAFABP + ibuprofen
2qm9 - mAFABP + troglitazone – mouse
2q9s - mAFABP + linoleate
3hk1, 3js1, 3jsq - mAFABP + inhibitor

Flight muscle fatty acid-binding protein

2flj - LMFABP – locust

Testis fatty acid-binding protein

4a60 - hTFABP

Extracellular fatty acid-binding protein

2kt4 - qEXFABP – quail
2lbv - qEXFABS + enterobactin
3sao - cEXFABP + myristoyl lysophosphatidic acid

2poa - FABP (mutant) - Schistosoma mansoni – NMR