1fdq

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CRYSTAL STRUCTURE OF HUMAN BRAIN FATTY ACID BINDING PROTEINCRYSTAL STRUCTURE OF HUMAN BRAIN FATTY ACID BINDING PROTEIN

Structural highlights

1fdq is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FABP7_HUMAN B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1fdq, resolution 2.10Å

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OCA