3D structures of fatty acid synthase3D structures of fatty acid synthase
Updated on 25-July-2021
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- Fatty acid synthase; Domains – KS-MAT 2-963; MAT 422-823; enoyl-ACP-reductase 1529-1867; ACP 2114-2202; thioesterase 2221-2502
- 1xkt, 4z49 – hFAS thioesterase domain – human
- 2jfd – hFAS MAT domain
- 3hhd - hFAS KS-MAT domain
- 4w82 – hFAS enoyl- ACP-reductase domain
- 2cf2, 2vz8 – pFAS – pig
- 2png – FAS ACP domain – rat
- 5my2 – FAS KS-MAT DI domain – mouse
- 2uv8, 3hmj, 6ql9 – yFAS α+β subunits - yeast
- 6jsh, 6jsi, 6ql5, 6ql6, 6ta1, 6u5t, 6u5u, 6wc7 - yFAS α+β subunits – Cryo EM
- 2pff, 2was, 2ml8 – yFAS α subunit
- 6fn6 – FAS – Drosophila melanogaster
- 1kp9 – MtFAS CmaA1 – Mycobacterium tuberculosis
- 4v8w, 6gjc – MtFAS I – Cryo-EM
- 4v8l – FAS – Mycobacterium smegmatis – Cryo-EM
- 4v58 – TlFAS – Thermomyces lanuginosus
- 6u5v, 6u5w - FAS α+β subunits – Candida albicans - Cryo EM
- 7bc4 - PpFAS α+β subunits – Pischia pastoris - Cryo EM
- 7bc5 - PpFAS α subunit ACP domain - Cryo EM
- FAS complex with fatty acid
- 3tjm – hFAS thioesterase domain + fatty acid
- 1kpg – MtFAS CmaA1 + cetyl-trimethyl-ammonium + adenosyl homocysteine
- 1kph – MtFAS CmaA1 + didecyl-dimethyl-ammonium + adenosyl homocysteine
- 1kpi – MtFAS CmaA2 + didecyl-dimethyl-ammonium + adenosyl homocysteine
- 3hem - MtFAS CmaA1 + dioctylamine
- FAS complex with reactants
- 2jfk – hFAS MAT domain + malonyl CoA
- 2vz9 – pFAS + NADP
- 5my0 - mFAS KS-MAT domain + malonyl CoA
- 6rop - mFAS KS-MAT domain + octanoyl CoA
- 2wat – yFAS α subunit + CoA
- 4v59 – TlFAS + NADP
- FAS complex with protein
- 2cg5 - hFAS ACP domain + AASD-PPT
- 6ql7 – yFAS α+β subunits + translation machinery-associated protein 17
- FAS complex with inhibitor
- 2px6 – hFAS thioesterase domain + orlistat
- 4piv, 5c37, 6nna – hFAS (mutant) + NADP + inhibitor
- 2vkz - yFAS α+β subunits + cerulenin
For FAS acyl carrier protein see Acyl carrier protein