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Crystal structure of mycolic acid cyclopropane synthase CmaA1, apo-formCrystal structure of mycolic acid cyclopropane synthase CmaA1, apo-form
Structural highlights
FunctionCMAS1_MYCTU Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences |
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