Rho guanine nucleotide exchange factor 3D structures

3D Structures of Rho guanine nucleotide exchange factor3D Structures of Rho guanine nucleotide exchange factor

Updated on 16-October-2023 {{#tree:id=OrganizedByTopic|openlevels=0|

• GEF guanine nucleotide exchange factor 1 (P115-GEFGEF)

• • 1iap – hGEF N terminal RGS domain 42-252 - human
    
  • 3odo, 3odw, 3odx – hGEF DH/PH domain 353-766
    
  • 3p6a – hGEF DH/PH domain (mutant)
    
  • 1shz, 3ab3 – hGEF N terminal RGS domain + guanine nucleotide-binding protein
    

• GEF guanine nucleotide exchange factor 2

• • 8bnt – hGEF-H1 DH domain 206-448 + RhoA
    
  • 7g80, 7g81, 7g82, 7g83, 7g84, 7g85, 7g86, 7g88, 7g89, 7g8a, 7g8b, 7g8c, 7g8d, 7g8e, 7g8f, 7g8g, 7g8h, 7g8i, 7g8j, 7g8k, 7g8l, 7g8m, 7g8n, 7g8o, 7g8p, 7g8q, 7g8r, 7g87, 7g8s, 7g8t, 7g8u, 7g8v, 7g8w, 7g8x, 7g8y, 7g8z, 7g90, 7g91, 7g92, 7g93, 7g94, 7g95, 7g96, 7g97, 7g98, 7g99, 7g9a, 7g9b, 7g9c, 7g9d, 7g9e, 7g9f, 7g9g, 7g9h, [[7g9i, 7g9j – hGEF-H1 DH domain + RhoA + inhibitor
    
  • 5efx – hGEF-H1 439-582
    

• GEF guanine nucleotide exchange factor 3

• • 2z0q – mGEF DH/PH domain - mouse
    

• GEF guanine nucleotide exchange factor 4 (Asef)

• • 2dx1 – hGEF 59-540
    
  • 2pz1 – hGEF 137-599
    
  • 3nmx, 3nmz – hGEF 170-276 + APC
    

• GEF guanine nucleotide exchange factor 6

• • 1ujy – hGEF SH3 domain 160-222 - NMR
    
  • 1wyr – hGEF CH domain 4-111 - NMR
    

• GEF guanine nucleotide exchange factor 7 (b-PIX)

• • 1by1 – hGEF DH domain 81-289 - NMR
    
  • 2l3g – hGEF CH domain 1-137 - NMR
    
  • 2esw – mGEF SH3 domain 7-63
    
  • 2g6f – rGEF SH3 domain – rat
    
  • 2w6b – rGEF coiled-coil domain 588-638
    

• GEF guanine nucleotide exchange factor 7 complex with peptide

• • 2ak5 – hGEF SH3 domain + CBL-b peptide
    
  • 2df6 – hGEF SH3 domain + PAK-1 peptide
    
  • 1zsg – hGEF residues 179-243 + PAK-1 peptide – NMR
    
  • 2p4r – rGEF SH3 domain + E3 ubiquitin protein ligase peptide
    
  • 3l4f – rGEF coiled-coil domain + SHANK1 PDZ domain
    

• GEF guanine nucleotide exchange factor 8 (PRONE8)

• • 3eo2 – hGEF residues 161-373
    
  • 4xh9 – hGEF DH/PH domain + transforming protein GEFA
    
  • 2ntx – AtGEF PRONE domain 76-440 – Arabidopasis thaliana
    
  • 2wbl – AtGEF PRONE domain + GTPase ROP7
    
  • 2nty – AtGEF PRONE domain + GTPase ROP4 + GDP
    

• GEF guanine nucleotide exchange factor 9 (collybistin)

• • 2ysq – hGEF SH3 domain - NMR
    
  • 4mt6, 4mt7 – rGEF (mutant)
    
  • 2dfk – rGEF II + CDC42
    

• GEF guanine nucleotide exchange factor 11

• • 2dls – hGEF PDZ domain 44-123 - NMR
    
  • 5e6p – hGEF PDZ domain + plexin-B2
    
  • 3kz1, 3t06 – hGEF DH/PH domain 710-1085 + transforming protein GEFA
    
  • 5jhg – hGEF DH/PH domain + transforming protein RhoA
    
  • 5jhh – hGEF DH/PH domain + transforming protein RhoA + inhibitor
    
  • 1xcg – hGEF DH/PH domain + transforming protein GEFA - NMR
    
  • 3cx6, 3cx8 – rGEF RGS domain 307-508 + guanine nucleotide-binding protein
    

• GEF guanine nucleotide exchange factor 12 (Leukemia-associated GEFGEF)

• • 1txd – hGEF DH/PH domain 764-1138
    
  • 2omj – hGEF PDZ domain 67-151
    
  • 1x86 – hGEF DH/PH domain (mutant) + transforming protein GEFA
    
  • 2os6 – hGEF PDZ domain + plexin peptide – NMR
    

• GEF guanine nucleotide exchange factor 16 (Ephexin-4)

• • 1x6b – hGEF SH3 domain 334-399 - NMR
    
  • 7cso, 7csp, 7csr – mGEF 261-713 (mutant)
    

• GEF guanine nucleotide exchange factor 18

• • 6bcb – mGEF 302-444 + transforming protein RhoA
    

• GEF guanine nucleotide exchange factor 25

• • 2rgn – hGEF 149-502 + transforming protein RhoA + guanine nucleotide-binding protein G(I)
    

• GEF guanine nucleotide exchange factor 28

• • 6bc1 – hGEF PH domain 1049-1194 + Ras-related C3 botulinum toxin substrate 1
    
  • 6bc0 – hGEF PH domain + transforming protein RhoA
    

}}