TRNA methyltransferase 3D structures

3D structures of tRNA methyltransferase3D structures of tRNA methyltransferase

Updated on 20-August-2024 - For a general description of the protein see TRNA methyltransferase

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• tRNA to N1 of guanine methyltransferase
  • 6w14 – MsTrm – Mycobacterium smegmatis
    
  • 6w15 – MsTrm + SAH
    
  • 7kff – CdTrm – Corynebacterium diphtheriae
    
  • 3knu, 8sh4 – ApTrm – Anaplasma phagocytophilum
    
• tRNA guanine 9 N1 methyltransferase
  • 4jwg – fyTrm – fission yeast
    
  • 4jwf, 4jwh – fyTrm + SAH
    
  • 4jwj – yTrm + SAH – yeast
    
• tRNA guanine 37 N1 methyltransferase or TrmD
  • 1oy5 – AaTrm – Aquifex aeolicus
    
  • 3ief – Trm – Bartonella henselae
    
  • 1uaj – HiTrm – Haemophilus influenzae
    
  • 3ky7 – SaTrm – Staphylococcus aureus
    
  • 3quv, 6nvr, 7rey – MaTrmD – Mycobacterium abscessus
    
  • 5hjj, 5yac – PabTrm – Pyrococcus abyssi
    
  • 6jki – PaTrmD – Pseudomonas aeruginosa
    
  • 5zhi – MtTrm – Mycobacterium tuberculosis
    
  • 7myq – AbTrm – Acinetobacter baumannii
    
• Complexes of tRNA guanine 37 N1 methyltransferase
  • 1uak, 4yvg – HiTrmD + SAM
    
  • 1ual, 1uam – HiTrm + SAH
    
  • 3axz – HiTrmD + adenosine
    
  • 4mcb, 4mcc, 4mcd – HiTrmD + inhibitor
    
  • 4yvh – HiTrmD + SFG
    
  • 4yvi, 4yvj, 4yvk – HiTrmD + SFG + tRNA
    
  • 5d9f, 4ypw, 4ypx, 4ypy, 4ypz, 4yq0, 4yq1, 4yq2, 4yq3, 4yq4, 4yq5, 4yq6, 4yq7, 4yq8, 4yq9, 4yqa, 4yqb, 4yqc, 4yqg, 4yqi, 4yqj, 4yqk, 4yql, 4yqn, 4yqo, 4yqp, 4yqq, 4yqr, 4yqs, 4yqt, 4yqd – HiTrmD + SAM competitive
    
  • 2yx1 – MjTrm + SFG – Methanocalcococcus jannaschii
    
  • 3ay0 – MjTrm5 + adenosine
    
  • 4h3y, 4h3z – Trm + SAH – Burkholderia phymatum
    
  • 4ig6 – ApTrm + SAH
    
  • 1p9p – EcTrm + SAH – Escherichia coli
    
  • 4gek, 4iwn – EcTrm + SAM derivative
    
  • 5hr7 – EcTrm + tRNA-Glu
    
  • 5hji, 5hjm – PabTrm + adenosine derivative
    
  • 5hjk – PabTrm + SAH
    
  • 6qo2, 6qo3, 6qo4, 6qo6, 6qoa, 6qoc, 6qod, 6qoe, 6qof, 6qog, 6qoh, 6qoi, 6qoj, 6qok, 6qol, 6qom, 6qon, 6qoo, 6qop, 6qoq, 6qor, 6qos, 6qot, 6qou, 6qov, 6qow, 6qox, 6qqq, 6qqr, 6qqt, 6qqu, 6qqv, 6qqw, 6qqz, 6qr0, 6qr1, 6qr2, 6qr3, 6qr4, 6qr7, 6qr9, 6qra, 6qrc, 6qrd, 6qre, 6qrf, 6qrg – MaTrmD + inhibitor
    
  • 6nw6 – MaTrmD + SAM
    
  • 6nw7, 7rez, 7rf0 – MaTrmD + SAH
    
  • 6joe, 6jof, 5zhm, 5zhn, 6afk – PaTrmD + inhibitor
    
  • 6wyq – PaTrmD + SAM
    
  • 6wyr – PaTrmD + SFG
    
  • 5zhj – MtTrmD + SAH
    
  • 5zhk, 5zhl – MtTrm + inhibitor
    
  • 5wt1 – PabTrm5a + tRNA + SAH
    
  • 5hji – PabTrm5a + adenosine
    
  • 5wt3 – PabTrm5a + tRNA + methylthioadenosine
    
  • 7mys – AbTrmD + SAH
    
  • 7kff – CdTrmD + SAH
    
• tRNA guanine 46 N7 methyltransferase
  • 2vdu, 2vdv – yTrm8
    
  • 1yzh – Trm – Streptococcus pneumoniae
    
  • 2fca, 7nzj – BsTrmB – Bacillus subtilis
    
  • 3dxx – EcTrmB
    
• Complexes of tRNA guanine 46 N7 methyltransferase
  • 3ckk – hTrm + SAM - human
    
  • 7pl1 – hTrm + sinefungin
    
  • 7ogj – hTrm + SAH
    
  • 3dxy – EcTrmB + SAM
    
  • 3dxz – EcTrmB + SAH
    
  • 7nyb – BsTrmD + SAM
    
  • 7nzi – BsTrmD + SAH
    
• Trm to O2 of guanosine 18
  • 7edc – EcTrmH (mutant) + SAM
    
• Trm to O2 of cytidine 32
  • 4cnd – EcTrmJ (mutant)
    
  • 4xbo – EcTrmJ + SAH
    
  • 4cne – EcTrmJ (mutant) + SAH
    
• tRNA cytidine 34 O2 methyltransferase YibK
  • 6jp6 – yTrm7
    
  • 3e5y – BpTrmH – Burkholderia pseudomalllei
    
  • 4jak, 4kdz – EcTrmL
    
  • 7e3s – TrmL – Shewanella oneidensis<br />
  • 7e3r – VvTrmL – Vibrio vulnificus
    
  • 1j85, 6ahw, 7d51 – HiYibK
    
  • 6qkv, 6qh8 – PaYibK
    
  • 6ahw – HiTrm
    
• Complexes of tRNA cytidine 34 O2 methyltransferase
  • 6jpl – yTrm7 + SAM
    
  • 4kgn – BpTrm + SAH
    
  • 3n4k, 3n4j – Trm + SAH – Yersinia pestis
    
  • 1mxi, 1im8 – HiTrm + SAH
    
  • 4jal – EcYibK + SAH
    
  • 7e3q – VvTrm + SAH
    
• Trm to C5 of cytidine 38
  • 6fdf – fyTrm + SAH
    
• Trm to O2 of cytidine/uridine
  • 5gra – TrmJ – Zymomonas mobilis
    
  • 5gmc, 5gmb – PaTrmJ
  • 5gm8 – PaTrmJ + SFG
    
• tRNA guanine 6 N2 methyltransferase
  • 3tm5 – PfTrm14 + SFG – Pyrococcvus furiosus
    
  • 3tlj – PfTrm14 + SAH
    
  • 3tm4 – PfTrm14 + SAM
    
• Trm to N2 of guanine 10
  • 6zxy – AfTrm11 – Archaeoglobus fulgidus
    
  • 6zxv, 6zxw – AfTrm11 + SFG
    
• Trm M2G/M22G10
  • 5e71 – TkTrm – Thermococcvus kodakarensis
    
  • 5e72 – TkTrm + SAM
    
• Trm to N1 of adenine 9
  • 5a7t, 5a7z – SaTrm – Sulfolobus acidocaldarius
    
  • 4cnf – SaTrm (mutant)
    
  • 5a7y – SaTrm + SAH
    
  • 4cng – SaTrm (mutant) + SAH
    
• Trm to N1 of adenine 22
  • 6q56 – BsTrm (mutant)
    
  • 6qe6 – TrmK + SAH - Mycoplasma capricolum
    
  • 7o4m – SaTrm
    
  • 7o4o – SaTrm + SAH
    
  • 7o4n – SaTrm + SAM
    
• tRNA adenine 58 N1 methyltransferase
  • 5ccb, 5cd1 – hTrm + SAH + tRNA-Lys
    
  • 5ccx – hTrm + tRNA-Lys
    
  • 5eqj – yTrm6
    
  • 5erg – yTrm6 + SAM
    
  • 2pwy – TtTrm – Thermus thermophilus
    
  • 5c0o, 5c1i – TtTrm (mutant) + SAM
    
• Trm to uracil 34
  • 4qnx – EcTrm
    
  • 4qnu, 4qnv – EcTrm + SAM derivative
    
• Trm9-Trm112 to uracil 34
  • 5cm2 – Trm – Yarrowia lipolytica
    
• tRNA uracil 54 methyltransferase
  • 3bt7 – yTrmA + RNA
    
• Trm dual specificity
  • 4pl1, 4pl2 – EcTrm Rlmn (mutant) + SAM
    
  • 5hr7, 5hr6 – EcTrm RlmN (mutant) + tRNA-Glu
    
• Trm10 dual specificity to N1 of adenine 9/guanine 9
  • 7onu – hTrm10 in RNase P complex – Cryo EM
    
  • 6ems, 6emt – TkTrm10 (mutant)
    
  • 6emv – TkTrm10 (mutant) + SAH
    
  • 6emu – TkTrm10 (mutant) + SAM
    
• METTL6
  • 7f1e – hMETTL6 + SAM
    
  • 7ezg – hMETTL6 + SAH