Crystal structure of human METTL1 bound to SinefunginCrystal structure of human METTL1 bound to Sinefungin

Structural highlights

7pl1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TRMB_HUMAN Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.[1]

See Also

References

  1. Alexandrov A, Martzen MR, Phizicky EM. Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. RNA. 2002 Oct;8(10):1253-66. PMID:12403464

7pl1, resolution 1.85Å

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