Isocitrate dehydrogenase 3D structures: Difference between revisions
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Michal Harel (talk | contribs) New page: ==3D Structures of Isocitrate dehydrogenase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Isocitrate dehydroge... |
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*Isocitrate dehydrogenase | *Isocitrate dehydrogenase | ||
**[[5grh]] – hIDH3 α,γ subunits + Mg | **[[6kdf]] – hIDH3 α,β subunits - human<br /> | ||
**[[6kde]] – hIDH3 α,β subunits + Ca <br /> | |||
**[[5grh]] – hIDH3 α,γ subunits + Mg <br /> | |||
**[[3blx]] – yIDH - yeast<br /> | **[[3blx]] – yIDH - yeast<br /> | ||
**[[2uxq]] – DpIDH – ''Desulfotalea psychrophila''<br /> | **[[2uxq]] – DpIDH – ''Desulfotalea psychrophila''<br /> | ||
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**[[5z16]] – IDH –'' Acinetobacter baumannii''<br /> | **[[5z16]] – IDH –'' Acinetobacter baumannii''<br /> | ||
**[[5m2e]] - PaIDH – ''Pseudomonas aeruginosa''<br /> | **[[5m2e]] - PaIDH – ''Pseudomonas aeruginosa''<br /> | ||
**[[6ixl]] – OtIDH – ''Ostreococcus tauri''<br /> | |||
*IDH+citrate | *IDH+citrate | ||
**[[5yfn]] – hIDH1 + isocitrate+ Mg<br /> | **[[5yfn]] – hIDH1 + isocitrate+ Mg<br /> | ||
**[[5gri]] – hIDH3 | **[[5gri]] – hIDH3 α,γ subunits + citrate+ Mg<br /> | ||
**[[5h3f]] – mIDH 2 + isocitrate<br /> | |||
**[[5h3e]] – mIDH 2 (mutant) + isocitrate<br /> | |||
**[[2qfw]] – yIDH+isocitrate <br /> | **[[2qfw]] – yIDH+isocitrate <br /> | ||
**[[3blv]] – yIDH+citrate<br /> | **[[3blv]] – yIDH+citrate<br /> | ||
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**[[1hqs]] – IDH+citrate – ''Bacillus subtilis''<br /> | **[[1hqs]] – IDH+citrate – ''Bacillus subtilis''<br /> | ||
**[[4zda]] - IDH +isocitrate+Mn – ''Mycobacterium smegmatis''<br /> | **[[4zda]] - IDH +isocitrate+Mn – ''Mycobacterium smegmatis''<br /> | ||
**[[6ixu]] - OtIDH +isocitrate+Mg<br /> | |||
*IDH+NADP | *IDH+NADP | ||
**[[1t09]] – hIDH+NADP <br /> | **[[1t09]], [[5yfm]] – hIDH+NADP <br /> | ||
**[[3mar]] – hIDH (mutant) + NADP<br /> | **[[3mar]] – hIDH (mutant) + NADP<br /> | ||
**[[5k10]], [[5k11]] – hIDH + NADP – Cryo EM<br /> | **[[5k10]], [[5k11]] – hIDH + NADP – Cryo EM<br /> | ||
**[[5svn]], [[5svo]] – hIDH2 (mutant) + NADP<br /> | **[[5svn]], [[5svo]] – hIDH2 (mutant) + NADP<br /> | ||
**[[6kdy]], [[6ke3]] – hIDH3 α,β + NADH<br /> | |||
**[[5yvt]] – hIDH α+γ + NADH<br /> | **[[5yvt]] – hIDH α+γ + NADH<br /> | ||
**[[5yzh]] – mIDH+NADP – mouse<br /> | **[[5yzh]] – mIDH+NADP – mouse<br /> | ||
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**[[4hcx]], [[5kvu]] – IDH + NADP – ''mycobacterium tuberculosis''<br /> | **[[4hcx]], [[5kvu]] – IDH + NADP – ''mycobacterium tuberculosis''<br /> | ||
**[[6aj6]] – TbIDH (mutant) + NADP – ''Trypanosoma brucei''<br /> | **[[6aj6]] – TbIDH (mutant) + NADP – ''Trypanosoma brucei''<br /> | ||
**[[6ixt]] – OtIDH + NAD + Mg<br /> | |||
*IDH+α-ketoglutarate | *IDH+α-ketoglutarate | ||
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**[[6aj8]], [[6aja]], [[6ajb]] - TbIDH (mutant) +NADP + α-ketoglutarate <br /> | **[[6aj8]], [[6aja]], [[6ajb]] - TbIDH (mutant) +NADP + α-ketoglutarate <br /> | ||
*IDH binary complex | *IDH binary complex with inhibitor | ||
**[[ | **[[6q6f]] – hIDH1 (mutant) + inhibitor<br /> | ||
**[[3asj]] – TtIDH + inhbibitor<br /> | **[[3asj]] – TtIDH + inhbibitor<br /> | ||
*IDH higher complexes | *IDH higher complexes | ||
**[[3map]] - | **[[3map]], [[6pay]] - hIDH1 +NADP+isocitrate<br /> | ||
**[[3mas]] – | **[[3mas]] – hIDH1 (mutant) +NADP+isocitrate<br /> | ||
**[[1t0l]] – hIDH+NADP+isocitrate+Ca<br /> | **[[1t0l]] – hIDH+NADP+isocitrate+Ca<br /> | ||
**[[5gre]], [[5grf]] – hIDH3 α,γ subunits + ADP+ citrate+ Mg<br /> | **[[5gre]], [[5grf]] – hIDH3 α,γ subunits + ADP+ citrate+ Mg<br /> | ||
**[[5grl]] – hIDH3 α,γ subunits + ADP+ isocitrate+ Mg<br /> | **[[5grl]] – hIDH3 α,γ subunits + ADP+ isocitrate+ Mg<br /> | ||
**[[5l57]], [[5l58]] - | **[[5l57]], [[5l58]] - hIDH1 +NADP + inhibitor<br /> | ||
**[[4i3k]], [[4i3l]], [[4ja8]],[[4umx]], [[4umy]], [[4xrx]], [[4xs3]], [[5de1]], [[5lge]], [[5sun]], [[5svf]], [[6b0z]], [[5tqh]], [[6o2y]], [[6o2z]], [[6adg]] - hIDH1 (mutant) +NADP + inhibitor<br /> | **[[4i3k]], [[4i3l]], [[4ja8]],[[4umx]], [[4umy]], [[4xrx]], [[4xs3]], [[5de1]], [[5lge]], [[5sun]], [[5svf]], [[6b0z]], [[5tqh]], [[6o2y]], [[6o2z]], [[6adg]], [[6u4j]], [[6vei]], [[6vg0]] - hIDH1 (mutant) +NADP + inhibitor<br /> | ||
**[[6adi]] – hIDH2 (mutant) +NADP + inhibitor<br /> | **[[6bkx]], [[6bky]], [[6bkz]], [[6bl0]], [[6bl1]], [[6bl2]] – hIDH1 + isocitrate + inhibitor<br /> | ||
**[[6bkx]], [[6bky]], [[6bkz]], [[6bl0]], [[6bl1]], [[6bl2]] - | **[[6adi]], [[6vfz]] – hIDH2 (mutant) +NADP + inhibitor<br /> | ||
**[[6l57]], [[6l59]] – hIDH3 a+g + citrate + ATP<br /> | |||
**[[6bkx]], [[6bky]], [[6bkz]], [[6bl0]], [[6bl1]], [[6bl2]] - hIDH1 + isocitrate + inhibitor<br /> | |||
**[[5svf]] - hIDH (mutant) +NADP + citrate + inhibitor<br /> | **[[5svf]] - hIDH (mutant) +NADP + citrate + inhibitor<br /> | ||
**[[5i96]] – hIDH2 + NADP+ enasidenib + Ca<br /> | **[[5i96]] – hIDH2 + NADP+ enasidenib + Ca<br /> | ||
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**[[1idc]] - EcIDH (mutant)+oxalosuccinate+Mg<br /> | **[[1idc]] - EcIDH (mutant)+oxalosuccinate+Mg<br /> | ||
**[[6ajc]] - TbIDH (mutant) +NADP+isocitrate<br /> | **[[6ajc]] - TbIDH (mutant) +NADP+isocitrate<br /> | ||
**[[6ixn]] - OtIDH +NAD + citrate<br /> | |||
*IDH quaternary complexes | *IDH quaternary complexes | ||
**[[5svf]] – hIDH1 (mutant) +NADP + citrate + inhibitor<br /> | **[[5svf]], [[6io0]] – hIDH1 (mutant) +NADP + citrate + inhibitor<br /> | ||
**[[1hj6]] – EcIDH (mutant)+NADP+isopropylmalate+Mg<br /> | **[[1hj6]] – EcIDH (mutant)+NADP+isopropylmalate+Mg<br /> | ||
**[[1ai3]] - EcIDH +isocitrate+Mg+NDP<br /> | **[[1ai3]] - EcIDH +isocitrate+Mg+NDP<br /> | ||
Revision as of 13:33, 27 August 2020
3D Structures of Isocitrate dehydrogenase3D Structures of Isocitrate dehydrogenase
Updated on 27-August-2020