6ixn

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Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and citrateCrystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and citrate

Structural highlights

6ixn is a 4 chain structure with sequence from Ostreococcus tauri. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.87Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

IDH_OSTTA Performs an essential role in the oxidative function of the tricarboxylic acid cycle and respiration (Probable). Catalyzes the decarboxylation of isocitrate to produce 2-oxoglutarate and generate NADH to provide electrons for energy production (Probable).[1]

See Also

References

  1. Tang WG, Song P, Cao ZY, Wang P, Zhu GP. A unique homodimeric NAD(+)-linked isocitrate dehydrogenase from the smallest autotrophic eukaryote Ostreococcus tauri. FASEB J. 2015 Jun;29(6):2462-72. doi: 10.1096/fj.14-257014. Epub 2015 Feb 27. PMID:25724193 doi:http://dx.doi.org/10.1096/fj.14-257014

6ixn, resolution 1.87Å

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OCA