Fatty acid-binding protein: Difference between revisions
No edit summary |
No edit summary |
||
| Line 78: | Line 78: | ||
[[3sao]] - cEXFABP + myristoyl lysophosphatidic acid | [[3sao]] - cEXFABP + myristoyl lysophosphatidic acid | ||
[[2poa]] - FABP (mutant) - Schistosoma mansoni – NMR<BR /> | [[2poa]] - FABP (mutant) - ''Schistosoma mansoni'' – NMR<BR /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 13:42, 28 March 2012
Fatty acid-binding protein (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells. Some FABSs are linked to metabolic and inflammatory pathways. Various FABS differ in their tissue expression. IFABP is intestinal; HFABP is heart-type; BFABP is brain-type; LFABP is liver-type; AFABP is adipocyte; LMDABP is from flight muscle; TFABP is from testis; EXFABP is extracellular.
3D structures of fatty acid-binding protein3D structures of fatty acid-binding protein
Intestinal fatty acid-binding protein
1ael, 1a57, 1sa8 - rIFABP – rat – NMR
1t8v - rIFABP (mutant) – NMR
1kzw - hIFABP – human – NMR
1kzx - hIFABP (mutant) – NMR
Intestinal fatty acid-binding protein binary complex
3akm - hIFABP + fatty acid analog
3akn - rIFABP + fatty acid analog
1ure - rIFABP + palmitate – NMR
Heart-type fatty acid-binding protein
1g5w - hHFABP – NMR
Brain-type fatty acid-binding protein
1fdq - hBFABP
1fe3 - hBFABP + oleate
Liver-type fatty acid-binding protein
1p6p - LFABP – toad
1tvq - cLFABP – chicken
1zry - cLFABP - NMR
2f73,-3stn - hLFABP
2py1, 2l67, 2l68 - hLFABP – NMR
2ju3, 2ju7 - rLFABP – NMR
2ft9 – AmLFABP - Ambystoma mexicanum
Liver-type fatty acid-binding protein binary complex
3stk, 3stm - hLFABP + palmitate
2ju8 - rLFABP + oleate – NMR
1tw4 - cLFABP + cholate
2jn3 - cLFABP + chenodeoxycholate
2k62 - cLFABP + bile acid-based Gd chelate
2ftb - AmBFABP + oleate
Adipocyte fatty acid-binding protein
1tou, 2hnx, 3q6l, 3rzy - hAFABP
1tow - hAFABP + carbazole butanoic acid
2nnq, 3fr2, 3fr4, 3fr5 - hAFABP + inhibitor
3p6c - hAFABP + citrate
3p6d, 3p6e - hAFABP + propionate derivative
3p6f - hAFABP + phenyl-butyrate
3p6g, 3p6h - hAFABP + ibuprofen
2qm9 - mAFABP + troglitazone – mouse
2q9s - mAFABP + linoleate
3hk1, 3js1, 3jsq - mAFABP + inhibitor
Flight muscle fatty acid-binding protein
2flj - LMFABP – locust
Testis fatty acid-binding protein
4a60 - hTFABP
Extracellular fatty acid-binding protein
2kt4 - qEXFABP – quail
2lbv - qEXFABS + enterobactin
3sao - cEXFABP + myristoyl lysophosphatidic acid
2poa - FABP (mutant) - Schistosoma mansoni – NMR