Transposase 3D structures

3D structures of transposase3D structures of transposase

Updated on 16-May-2022 - For a general description of the protein see Transposase

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• Mu transposase
  • 1tns, 1tnt – MuMuA DNA-binding domain – enterobacteria phage Mu - NMR
    
  • 1bcm, 1bco – MuMuA core domain
    
  • 2ezh, 2ezi – MuMuA Iγ subdomain - NMR
    
  • 2ezk, 2ezl – MuMuA Iβ subdomain - NMR
    
  • 4fcy – MuMuA + DNA
    
  • 1f6v – MuA C terminal – Escherichia virus Mu - NMR
    
• Hermes transposase
  • 2bw3 – fTra (mutant) - fly
    
  • 4d1q, 6dx0, 6dww, 6dwy, 6dwz – fTra (mutant) + DNA
    
• Dra2 transposase
  • 2xm3 – Dra2 + Dra2 transposase binding element + DNA – Deinococcus radiodurans
    
  • 2xma, 2xqc – Dra2 + DNA
    
  • 2xo6 – Dra2 (mutant) + DNA
    
• Tn5 transposase
  • 1muh, 1mus, 1mm8, 3ecp, 4dm0 – EcTn5 (mutant) + DNA – Escherichia coli
    
• Tn7 transposase
  • 1f1z – EcTn7 tnsA
    
  • 5d17 – EcTn7 tnsE C terminal
    
  • 5d16 – EcTn7 tnsE C terminal (mutant)
    
  • 1t0f – EcTn7 tnsA + tnsC
    
  • 7m9a, 7m9b, 7m9c – hTn7 tnsC + DNA + ADP – Cryo EM
    
  • 7n6i – ShTn7 tnsC + TniQ + DNA + ATP – Scytonema hofmannii - Cryo EM
    
  • 7m99 – ShTn7 tnsC + DNA + ATPgS - Cryo EM
    
  • 7plh – ShTn7 tnsC + DNA + AMPPNP Cryo EM
    
  • 7pla – ShTn7 cas12k + DNA + RNA - Cryo EM
    
• Mos1 transposase
  • 2f7t – DmMos1 catalytic domain (mutant) – Drosophila mauritiana
    
  • 4u7b, 5hoo – DmMos1 + DNA
    
  • 3hos, 3hot, 4r79 – DmMos1 (mutant) + DNA
    
  • 4mda, 4mdb – DmMos1 catalytic domain (mutant) + drug
    
• Tc3 transposase
  • 1tc3, 1u78 – Tc3 DNA-binding domain (mutant) + DNA – Caenorhabditis elegans
    
• Orfa transposase (Is608)
  • 2a6m – HpOrfa – Helicobacter pylori
    
  • 2vhg, 2a6o, 2vic, 2vih, 2vju, 2vjv – HpOrfa + DNA
    
• Sleeping beauty transposase
  • 5cr4 – SB catalytic domain – synthetic
    
  • 2m8e – SB PAI domain – synthetic - NMR
    
  • 5unk – OmRED domain – Oncorhynchus mykiss - NMR
    
  • 6urs – OmSB PAI domain - NMR
    
• DNA-mediated transposase
  • 6pqr, 6pqu, 6pqx, 6pr5 – DMT – corn earthworm moth – Cryo EM
    
• P element transposase
  • 6pe2, 6p5a – DmPET + DNA – Cryo EM
    
  • 3kde – DmPET THAP domain + DNA
    
• Piggyback transposase
  • 6x68, 6x67 – clPBT + DNA – cabbage looper – Cryo EM
    
  • 5lme – clPBT C terminal - NMR
    
• ISC transposase
  • 6xg8, 6xgx, 6xgw – ISC + DNA – Hungateiclostridium thermocellum
    
  • 6dgc – ISC C-terminal catalytic domain - Sulfolobus
    
• TniQ transposase
  • 6lnd, 6v9p – VcTniQ – Vibrio Cholerae
    
  • 6lnc, 6lnb, 6pig, 6pif, 6pij, 6uvn – VcTniQ + Cas6 + Cas7 + Cas8 + RNA – Cryo EM
    
  • 7oxd – ShTn7 TniqQ
    
• Heltiron transposase
  • 7lcc – HT + DNA – bat – Cryo EM