1tc3

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TRANSPOSASE TC3A1-65 FROM CAENORHABDITIS ELEGANSTRANSPOSASE TC3A1-65 FROM CAENORHABDITIS ELEGANS

Structural highlights

1tc3 is a 3 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.45Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TC3A_CAEEL Binds specifically to the terminal nucleotides of the TC3 inverted repeat. Its expression results in frequent excision and transposition of endogenous TC3 elements. TC3 transposase acts by making double strand breaks at the ends of TC3 element. The excised element would then be inserted into a target sequence.

See Also

1tc3, resolution 2.45Å

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OCA