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[[Image:1g1x.gif|left|200px]]


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==STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA==
The line below this paragraph, containing "STRUCTURE_1g1x", creates the "Structure Box" on the page.
<StructureSection load='1g1x' size='340' side='right'caption='[[1g1x]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1g1x]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekc 1ekc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G1X FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g1x OCA], [https://pdbe.org/1g1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g1x RCSB], [https://www.ebi.ac.uk/pdbsum/1g1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g1x ProSAT]</span></td></tr>
{{STRUCTURE_1g1x| PDB=1g1x |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RS6_THET8 RS6_THET8] Located on the outer edge of the platform on the body of the 30S subunit.[HAMAP-Rule:MF_00360]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/1g1x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g1x ConSurf].
<div style="clear:both"></div>


'''STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA'''
==See Also==
 
*[[Ribosomal protein S15|Ribosomal protein S15]]
 
*[[Ribosomal protein S18|Ribosomal protein S18]]
==Overview==
*[[Ribosomal protein S6|Ribosomal protein S6]]
The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a 104-nucleotide RNA fragment composed of two three-helix junctions that lie at the end of a central helix, and the ribosomal proteins S15, S6, and S18. S15 binds the ribosomal RNA early in the assembly of the 30S ribosomal subunit, stabilizing a conformational reorganization of the two three-helix junctions that creates the RNA fold necessary for subsequent binding of S6 and S18. The structure of the complex demonstrates the central role of S15-induced reorganization of central domain RNA for the subsequent steps of ribosome assembly.
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
1G1X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekc 1ekc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA].
 
==Reference==
Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10753109 10753109]
[[Category: Protein complex]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Agalarov, S C.]]
[[Category: Agalarov SC]]
[[Category: Funke, P M.]]
[[Category: Funke PM]]
[[Category: Prasad, G S.]]
[[Category: Prasad GS]]
[[Category: Stout, C D.]]
[[Category: Stout CD]]
[[Category: Williamson, J R.]]
[[Category: Williamson JR]]
[[Category: Ribosomal proteins s15]]
[[Category: Ribosome]]
[[Category: Rna]]
[[Category: S18]]
[[Category: S30 ribosomal subunit]]
[[Category: S6]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 17:01:54 2008''

Latest revision as of 10:21, 7 February 2024

STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNASTRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA

Structural highlights

1g1x is a 10 chain structure with sequence from Thermus thermophilus. This structure supersedes the now removed PDB entry 1ekc. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RS6_THET8 Located on the outer edge of the platform on the body of the 30S subunit.[HAMAP-Rule:MF_00360]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1g1x, resolution 2.60Å

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