Ribosomal protein S15

Ribosomal protein S15 (RPS15) is one of the 21 proteins which belong to the 30S of the bacterial ribosome or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It is involved in the early steps of ribosome assembly^[1].

Relevance

RPS15 phosphorylation mediates leucine-rich kinase 2 neurodegeneration in Parkinson's disease^[2].

3D Structures of Ribosomal protein S153D Structures of Ribosomal protein S15

Updated on 10-October-2017

- 3iy8 - EcRPS15+EcRPS5+EcRPS6+EcRPS9+ EcRPS8+EcRPS11+EcRPS12+EcRPS16+EcRPS17+EcRPS18+Leishmania taretolae mRNA
- 1g1x - TtRPS15+TtRPS6+TtRPS18+16S RRNA fragment
- 1qd7 – TtRPS15+TtRPS4+TtRPS5+TtRPS7+TtRPS8+TtRPS6+TtRPS17+TtRPS20+16S RRNA fragment

ReferencesReferences

↑ Serganov A, Ennifar E, Portier C, Ehresmann B, Ehresmann C. Do mRNA and rRNA binding sites of E.coli ribosomal protein S15 share common structural determinants? J Mol Biol. 2002 Jul 26;320(5):963-78. PMID:12126618 doi:http://dx.doi.org/10.1016/S0022283602005533
↑ Martin I, Kim JW, Lee BD, Kang HC, Xu JC, Jia H, Stankowski J, Kim MS, Zhong J, Kumar M, Andrabi SA, Xiong Y, Dickson DW, Wszolek ZK, Pandey A, Dawson TM, Dawson VL. Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease. Cell. 2014 Apr 10;157(2):472-85. doi: 10.1016/j.cell.2014.01.064. PMID:24725412 doi:http://dx.doi.org/10.1016/j.cell.2014.01.064

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Alexander Berchansky, Michal Harel, Joel L. Sussman

[1] Serganov A, Ennifar E, Portier C, Ehresmann B, Ehresmann C. Do mRNA and rRNA binding sites of E.coli ribosomal protein S15 share common structural determinants? J Mol Biol. 2002 Jul 26;320(5):963-78. PMID:12126618 doi:http://dx.doi.org/10.1016/S0022283602005533

[2] Martin I, Kim JW, Lee BD, Kang HC, Xu JC, Jia H, Stankowski J, Kim MS, Zhong J, Kumar M, Andrabi SA, Xiong Y, Dickson DW, Wszolek ZK, Pandey A, Dawson TM, Dawson VL. Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease. Cell. 2014 Apr 10;157(2):472-85. doi: 10.1016/j.cell.2014.01.064. PMID:24725412 doi:http://dx.doi.org/10.1016/j.cell.2014.01.064

[1]

[2]

Ribosomal protein S15

Relevance

3D Structures of Ribosomal protein S153D Structures of Ribosomal protein S15

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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