Cytochrome c oxidase 3D structures

3D Structures of Cytochrome c oxidase3D Structures of Cytochrome c oxidase

Updated on 27-February-2025

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• Mammalian CcO or complex IV
  • 5z62 - CcO – human – Cryo EM
    
  • 1occ, 2occ, 1v54, 2dyr, 2zxw, 3abl, 3abm, 3asn, 3aso, 3x2q, 6nmp, 6j8m, 7tie, 7tih, 7tii, 7xma, 7y44, 7ypy, 8gcq – bCcO oxidized – bovine
    
  • 2eil, 2ein, 5b1a, 5xdq, 7coh, 7ypy, 8h8r, 8h8s - bCcO oxidized + metal
    
  • 1ocr, 1v55, 2eij, 3ag1, 6jy4, 7thu – bCcO reduced
    
  • 6juw – bCcO in catalytic intermediate
    
  • 2eik, 2eim, 5b1b, 5xdx, 6nmf - bCcO reduced + metal
    
  • 3abk, 3ag3, 8ijn - bCcO reduced + NO
    
  • 3ag2, 8gbt - bCcO reduced + CO
    
  • 3ag4, 7vuw, 7vvr, 7w3e - bCcO reduced + CN
    
  • 7vuw - bCcO oxidized + CN
  • 1ocz, 5zcq, 5zcp, 5zco, 5z86, 5z85, 5z84, 8gvm – bCcO + N3
    
  • 2y69, 3wg7, 6jy3 – bCcO + O2
    
  • 6nkn - bCcO + O
    
  • 7xmb, 8d4t - bCcO + inhibitor
    
  • 1oco, 5b3s, 5x1f, 5x1b, 5x19, 5wau, 5w97, 7coh, 7cp5, 7d5w, 7d5x, 7ev7 - bCcO + CO
    
  • 2dys – bCcO + lipids
    
  • 5luf – bCcO in respirasome – Cryo EM
    
  • 2ybb – bCcO + cytochrome bc1 complex + NADH-quinone oxidoreductase – Cryo EM
    
  • 5iy5 – bCcO + cytochrome c
    
  • 7o37, 7o3c, 7o3e - mCcO in complex III – mouse - Cryo EM
    
  • 7jro, 7jrp – CcO in complex IV – mung bean – Cryo EM
    
  • 6t0b, 6t15, 6ymx, 6ymy, 7z10, 8dh6, 8e7s, 8ec0, 9c8o – yCcO – yeast – Cryo EM
    
  • 7biu – yCcO
    
  • 6hu9, 6giq – yCcO in Bc1 complex
    
  • 6zdb – yCcO subunit 13 - NMR
    
  • 8c8q – CcO – fission yeast – Cryo EM
    
• Bacterial CcO
  • 1ar1, 1qle – PdCcO + antibody – Paracoccus denitrificans
    
  • 3ehb – PdCcO (mutant)
    
  • 3hb3 - PdCcO
    
  • 7ate, 7atn, 7au3, 7au6 – PdCcO – Cryo EM
    
  • 1m56 – RsCcO – Rhodoacter sphaeroides
    
  • 1m57 – RsCcO (mutant)
    
  • 2gsm – RsCcO subunit I+II
    
  • 3fye - RsCcO subunit I+II reduced
    
  • 3om3, 3oma, 3omi, 3omn, 6ci0 - RsCcO subunit I+II reduced (mutant)
    
  • 3fyi - RsCcO subunit I+II reduced + CN
    
  • 3dtu - RsCcO subunit I+II + deoxycholic acid
    
  • 6pw1 - RsCcO subunit I+II (mutant)
    
  • 6pw0 - RsCcO subunit I+II (mutant) + OH
    
  • 5weh - RsCcO subunit I+II+III polypeptide
    
  • 1xme, 2qpd, 2qpe, 3bvd, 3s8f, 3s33, 3s38, 3s39, 3s3a, 3s3b, 3s3c, 3s3d – TtCcO subunit I+II – Thermus thermophilus
    
  • 5u7n, 6ptt, 6pty - TtCcO subunit II
    
  • 3eh3, 3eh4, 3eh5 – TtCcO reduced
    
  • 3qjq, 3qjr, 3qjs, 3qjt, 3qju, 3qjv, 8ajz, 8k65, 8k6y – TtCcO subunits I+II+IIA + CO
    
  • 3s8g, 4fa7, 4faa – TtCcO (mutant)
    
  • 4n4y - TtCcO (mutant) + H2O2
    
  • 2lln – TtCcO subunit II - NMR
    
  • 2yev - TtCcO subunit I,IIC,III,IV
    
  • 4g70, 4g71, 4g72, 4g7q, 4g7r, 4g7s, 4gp4, 4gp5, 4gp8 - TtCcO subunit I (mutant),II,IIA
    
  • 2fwl – TtCcO subunit II + cytochrome C552
    
  • 3mk7, 5djq – CcO + peptide – Pseudomonas stutzeri
    
  • 1w2l - CcO subunit II – Rhodothermus marinus
    
  • 4txv - CcO subunit II + TlpA – Bradyrhizobium diazoefficiens
    
  • 4w9z - CcO subunit II – Bradyhisobium diazoefficiens
    
  • 6hwh, 6adq - CcO subunit I+II+III + ubiquinol cytochrome c reductase – Mycobacterium smegmatis – Cryo EM
    
  • 7e1v, 9dm1 - MsCcO in complex III – Cryo EM
    
  • 7rh5, 8ovc, 8ovd - MsCcO in complex III/IV – Cryo EM
    
  • 7e1w, 7e1x, 7rh6, 7rh7 - MsCcO in complex III + drug – Cryo EM
    
  • 6xkw, 6xkx, 6xkz - CcO in Bc1 complex – Rhodobacter capsulatus – Cryo EM
    
  • 7w5z, 8b6h - CcO in complex IV – Tetrhymena thermophila - Cryo EM
    
  • 7qho - CgCcO in complex IV – Corynebacterium glutamicum - Cryo EM
    
  • 7q21, 7qhm - CgCcO in complex III/IV - Cryo EM
    
  • 7rhe - CcO in respiratory complex + drug – Mycobacterium tuberculosis – Cryo EM
    
  • 7deg - CcO subunit I, II, IIa – Aquifex aeolicus – Cryo EM
    
  • 8ucj, 8uck – KpCcO + synaptic vesicular amine transporter – Komagataella pastoris – Cryo EM
    
  • 8ucm, 8ucp – KpCcO + synaptic vesicular amine transporter + drug – Cryo EM
    
  • 8ucn – KpCcO + synaptic vesicular amine transporter + histamine – Cryo EM
    
  • 8uco – KpCcO + synaptic vesicular amine transporter + amphetamine – Cryo EM
    
  • 8ucl – KpCcO + synaptic vesicular amine transporter + inhibitor – Cryo EM
    
• Ba3-type CcO
  • 1ehk, 5ndc, 8hua – TtCcO subunits I,II,IIA