Adaptin 3D structures

3D structures of Adaptin3D structures of Adaptin

Updated on 11-September-2024

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• AP1γ
  • 1iu1 – hAP1γ-1 appendage domain 662-785 – human
    
  • 4bcx – hAP1γ-2 appendage domain
    
  • 2e9g – hAP1γ-2 appendage domain - NMR
    
  • 2ymt, 3zhf – hAP1γ-2 appendage domain + peptide
    
  • 2a7b – mAP1γ-1 appendage domain – mouse
    
  • 1gyw, 1gyv, 1gyu – mAP1γ-1 appendage domain (mutant)
    
  • 3zy7 – mAP1γ-1 appendage domain (mutant) - NMR
    
• AP1μ
  • 4emz, 4en2 – mAP1μ-1 sorting motif recognition domain 158-423 + NEF + MHC-I
    
• AP1β + AP1γ + AP1μ + AP1σ
  • 6cm9, 6d84 – hAPβ-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + NEF + GTP - Cryo EM
    
  • 6dff, 6cri – hAP1β-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + NEF + ARF1 + GTP - Cryo EM
    
  • 4p6z – mAP1β-1 + hAP1-γ-1 + mAP1μ-1 + hAP1σ-1 + VPU + bone marrow stromal antigen peptide
    
  • 4hmy – mAP1β-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + ARF1 + GTP
    
  • 1w63 – rAP1β-1 + mAP1γ-1 + mAP1μ-1 + mAP1σ-3 - rat
    
• AP2α; domain - appendage 702-938
  • 1b9k, 1qts – mAP2α appendage domain
    
  • 1qtp – mAPα appendage domain (mutant)
    
  • 1ky6, 1kyd – mAP2α appendage domain + epsin peptide
    
  • 1ky7 – mAPα appendage domain + amphiphysin peptide
    
  • 1kyf, 1kyu – mAP2α appendage domain + eps15 peptide
    
  • 1w80, 2vj0 – mAP2α2 appendage domain + synaptojanin peptide
    
  • 3hs8 – mAP2α appendage domain + intersectin peptide
    
• AP2β
  • 1e42 – hAP2β1 appendage domain - human
    
  • 2g30 – hAP2β1 appendage domain + ARH peptide
    
  • 3h1z – hAP2β1 appendage domain + PTDINSPKI-γ peptide
    
  • 3hs9 – hAP2β1 appendage domain + intersectin peptide
    
  • 2iv9 – hAP2β2 appendage domain + eps15 peptide
    
  • 2iv8 – hAP2β2 appendage domain + B-arrestin peptide
    
  • 6yai, 7om8 – hAP2β2 + clathrin – Cryo EM
    
  • 7ohi, 7ohz, 7oi5, 7oiq – hAP2β2 + F-BAR
    
  • 1mj7 – hAP2β4 appendage domain
    
• AP2γ
  • 1iu1 – hAP2γ1 appendage domain
    
  • 2e9g, 4bcx – hAP2γ2 appendage domain
    
  • 2ymt – hAP2γ2 appendage domain + peptide
    
  • 3zhf – hAP2γ2 appendage domain + large envelope protein peptide
    
  • 1gyu, 2a7b – mAP2γ1 appendage domain
    
  • 1gyv, 1gyw, 3zy7 – mAP2γ1 appendage domain (mutant)
    
• AP2μ; Domain - C-terminal 158-433
  • 6bnt – hAP2μ2 C-terminal + insulin receptor substrate peptide
    
  • 7ofp – rAP2μ1 C-terminal - rat
    
  • 4emz, 4en2 – mAP2μ1 C-terminal + NEF + MHC-I
    
  • 3h85 – rAP2μ1 C-terminal + PTDINSPKIγ peptide - rat
    
  • 2bp5 – rAP2μ2 + purinoceptor peptide
    
  • 1bw8, 1i31 – rAP2μ2 C-terminal + EGFR peptide
    
  • 1bxx – rAP2μ2 C-terminal + TGN38 peptide
    
  • 1hes – rAP2μ2 C-terminal + selectin peptide
    
  • 5c7z, 5fpi – rAP2μ2 C terminal + integrin peptide
    
  • 2pr9 – rAP2μ2 C-terminal + GABA receptor peptide
    
  • 5wrm, 5wrl, 5wrk – rAP2μ2 C-terminal + insulin receptor substrate peptide
    
• AP2α + AP2σ
  • 4nee – rAP2 + HIV-1 NEF
    
• AP2α2 + AP2β + AP2σ
  • 4uqi – rAP2 + VPU
    
• AP2α + AP2β + AP2μ + AP2σ
  • 2vgl – rAP2α2 + AP2β1 + AP2μ1 + AP2σ1
    
  • 4uqi – rAP2α2 + AP2β2 + AP2μ2 + AP2σ1
    
  • 2xa7 – rAP2α2 + APβ + APμ + APσ + cargo peptide
    
  • 6qh5 – rAPα + rAPβ + APμ-1 + APσ
    
  • 6uri – rAPα + hAPβ + hAPμ-1 + hAPσ + NEF
    
  • 6qh6, 6qh7 – rAPα + rAPβ + APμ-1 + APσ + TGN38 peptide + CD4 peptide
    
  • 6yah, 6yae – rAP2α2 + hAPβ + rAPμ + mAPσ – Cryo EM
    
  • 6yaf – rAPα2 + hAPβ + rAPμ + mAPσ + hTGN38 peptide – Cryo EM
    
  • 2jkr, 2jkt – mAP2α2 + AP2β1 + AP2μ1 + AP2σ1 + CD4 peptide
    
  • 6owo – mAP2α2 + APβ + APμ + APσ + NECAP – Cryo EM
    
  • 6oxl – mAP2α2 + APβ + APμ + APσ + NECAP + DNA – Cryo EM
    
  • 7rw8, 7rw9, 7rwb – mAP2α2 + APβ + APμ + APσ – Cryo EM
    
  • 7rwc – mAP2α2 + APβ + APμ + APσ + SGIP – Cryo EM
    
  • 7rwa, 8t1o – mAP2α2 + APβ + APμ + APσ + Tgn38 peptide – Cryo EM
    
  • 7oho, 7z5c – rAP2α2 + hAPβ + rAPμ + mAPσ
    
  • 6owt – rAP2α2 + rAPβ + mAPμ + rAPσ + tetherin – Cryo EM
    
• AP2β1 + AP2γ1 + AP2μ1 + AP2σ3
  • 6dff, 6d84, 6d83, 6cri, 6cm9 – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + tetherin-NEF – Cryo EM
    
  • 7ux3, 8d4c, 8d4d, 8d4e, 8d4f, 8d4g, 8d9r, 8d9s, 8d9t, 8d9u, 8d9w – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + NEF + MHC-I – Cryo EM
    
  • 7r4h – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + HSTING – Cryo EM
    
• AP2γ1 + AP2β1 + AP2μ1 + AP2σ1
  • 1w63 – mAP2
    
  • 4hmy – mAP2 + ADP-ribosylation factor
    
  • 4p6z – mAP2 + VPU + bone marrow stromal antigen
    
• AP3μ
  • 4ikn – rAP3μ1 + TGN38 sorting peptide
    
• AP3δ
  • 4afi - hAP3δ1/mVAMP7
    
• AP3μ + AP3δ
  • 7p3x, 7p3y, 7p3z – yAP3 – yeast - Cryo EM
    
• AP4β
  • 2mj7 - hAP4β appendage domain - NMR
    
• AP4μ
  • 3l81, 4mdr – hAP2μ1 C-terminal + amyloid beta-A4 peptide