6cri

Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimerStructure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer

6cri, resolution 6.80Å Show:Asymmetric Unit Biological Assembly Structural highlights 6cri is a 24 chain structure with sequence from Homo sapiens, Human immunodeficiency virus 1 and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 6.8Å Ligands: Experimental data: Check Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function AP1M1_MOUSE Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. See Also Adaptin 3D structures Protein Nef 3D structures Tetherin