6dm8

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Understanding the Species Selectivity of Myeloid cell leukemia-1 (Mcl-1) inhibitorsUnderstanding the Species Selectivity of Myeloid cell leukemia-1 (Mcl-1) inhibitors

Structural highlights

6dm8 is a 8 chain structure with sequence from Escherichia coli K-12 and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MALE_ECOLI Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.MCL1_MOUSE Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis.

See Also

6dm8, resolution 2.70Å

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OCA