5-hydroxytryptamine receptor 3D structures

3D structures of 5-hydroxytryptamine receptor3D structures of 5-hydroxytryptamine receptor

Updated on 28-August-2024 - For a general description of the protein see 5-hydroxytryptamine receptor

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• 5-HT 1A
  • 7e2z – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein – Cryo EM
    
  • 7e2y – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + serotonin– Cryo EM
    
  • 8fy8, 8fye, 8fyl, 8fyx – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + drug – Cryo EM
    
  • 8fyt – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + LSD + cholesterol – Cryo EM
    
  • 8pjk – hHT1A + guanine nucleotide-binding protein + inositol derivative + cholesterol – Cryo EM
    
  • 8jsp, 8pkm – hHT61A+ guanine nucleotide-binding protein + scFv + drug – Cryo EM
    
• 5-HT 1B
  • 4iaq, 4iar, 5v54 – hHT1B/cytochrome b562 (mutant) + drug - human
    
  • 7c61 – hHT1B/cytochrome b562 (mutant) + antibody
    
  • 6g79 – hHT1B + guanine nucleotide-binding protein
    
• 5-HT 1D
  • 7e32 – hHT1D + guanine nucleotide-binding protein + Scfv + serotonin – Cryo EM
    
• 5-HT 1E
  • 8ugy, 8uh3 – hHT1E + guanine nucleotide-binding protein + drug – Cryo EM
    
• 5-HT 1F
  • 7exd – hHT1F + guanine nucleotide-binding protein + Scfv + drug – Cryo EM
    
• 5-HT 2A
  • 6a93, 6a94, 7vod, 7voe, 7wc5, 7wc7, 7wc8, 7wc9, 8jt8 – hHT2A/cytochrome b562 (mutant) + drug
    
  • 7wc4 – hHT2A/cytochrome b562 (mutant) + serotonin
    
  • 7wc6 – hHT2A/cytochrome b562 (mutant) + LSD
    
  • 6wgt – hHT2A/cytochrome b562 + hallucinogen
    
  • 6wh4 – hHT2A/cytochrome b562 + agonist
    
  • 7ran, 8v6u – hHT2A + guanine nucleotide-binding protein + Scfv + agonist – Cryo EM
    
  • 8uwl – hHT2A + guanine nucleotide-binding protein + Scfv + drug – Cryo EM
    
• 5-HT 2B
  • 4nc3 – hHT2B/cytochrome b562 (mutant)
    
  • 4ib4 – hHT2B/cytochrome b562 (mutant) + drug
    
  • 7srq – hHT2B + LSD – Cryo EM
    
  • 7srs – hHT2B + arrestin + antibody + LSD – Cryo EM
    
  • [7srrl]] – hHT2B + guanine nucleotide-binding protein + Scfv + LSD – Cryo EM
    
  • 5tvn – hHT2B/cytochrome b562 (mutant) + LSD
    
  • 5tud – hHT2B/cytochrome b562 (mutant) + antibody
    
  • 6drx, 6dry, 6drz, 6ds0 – hHT2B/cytochrome b562 + agonist + cholesterol
    
• 5-HT 2C
  • 6bqg, 6bqh – hHT2C/cytochrome b562 (mutant) + ergotamine
    
  • 8dpf, 8dph, 8dpi – hHT2C + guanine nucleotide-binding protein + scFv + drug – Cryo EM
    
  • 8dpg – hHT2C + guanine nucleotide-binding protein + scFv + serotonin derivative – Cryo EM
    
• 5-HT 3A
  • 8axd – hHT3A – Cryo EM
    
  • 8bla, 8blb – hHT3A + drug – Cryo EM
    
  • 4pir – mHT3A + VHH15 - mouse
    
  • 6be1, 8bl8, 8c1w, 8c1z, 8c20, 8c21 – mHT3A – Cryo EM
    
  • 6his – mHT3A + drug
    
  • 6np0, 6w1j, 6w1m, 6w1y, 6y1z, 8aw2 – mHT3A + drug – Cryo EM
    
  • 8cc6, 8cc7 – mHT3A + inhibitor – Cryo EM
    
  • 6dg7, 6dg8, 6hin, 6hio, 6hiq, 8frz, 8fsb – mHT3A + serotonin – Cryo EM
    
  • 6y59, 6y5a, 6y5b – mHT3A (mutant) + serotonin – Cryo EM
    
  • 8frx, 8frw, 8fsp, 8fsz – mHT3A + agonist – Cryo EM
    
• 5-HT 4
  • 7xt9, 7xta – hHT4 + guanine nucleotide-binding protein + serotonin – Cryo EM
    
  • 7xt8 – hHT4 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM
    
• 5-HT 5A
  • 7um5, 7um6, 7um7 – hHT5A + minigo + guanine nucleotide-binding protein + scFv + drug – Cryo EM
    
  • 7um4 – hHT5A + PGS + quinolone derivative
    
• 5-HT 6
  • 7xtb – hHT6 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM
    
  • 8jlz – hHT6 + guanine nucleotide-binding protein + nanobody + agonist – Cryo EM
    
  • 7ys6 – hHT6 + guanine nucleotide-binding protein + scFv + serotonin – Cryo EM