4zaj

2.2 Angstrom Crystal Structure of a Human Arginyl-tRNA Synthetase2.2 Angstrom Crystal Structure of a Human Arginyl-tRNA Synthetase

Structural highlights

4zaj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.22Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SYRC_HUMAN Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.^[1]

References

↑ Bottoni A, Vignali C, Piccin D, Tagliati F, Luchin A, Zatelli MC, Uberti EC. Proteasomes and RARS modulate AIMP1/EMAP II secretion in human cancer cell lines. J Cell Physiol. 2007 Aug;212(2):293-7. PMID:17443684 doi:http://dx.doi.org/10.1002/jcp.21083

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OCA

[1] Bottoni A, Vignali C, Piccin D, Tagliati F, Luchin A, Zatelli MC, Uberti EC. Proteasomes and RARS modulate AIMP1/EMAP II secretion in human cancer cell lines. J Cell Physiol. 2007 Aug;212(2):293-7. PMID:17443684 doi:http://dx.doi.org/10.1002/jcp.21083

[1]

4zaj

2.2 Angstrom Crystal Structure of a Human Arginyl-tRNA Synthetase2.2 Angstrom Crystal Structure of a Human Arginyl-tRNA Synthetase

Structural highlights

Function

See Also

References

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4zaj

2.2 Angstrom Crystal Structure of a Human Arginyl-tRNA Synthetase2.2 Angstrom Crystal Structure of a Human Arginyl-tRNA Synthetase

Structural highlights

Function

See Also

References

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