4gon

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Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAMCrystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM

Structural highlights

4gon is a 3 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.72Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DMA_ECOLI Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication.

See Also

4gon, resolution 2.72Å

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OCA