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Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAMCrystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM
Structural highlights
FunctionDMA_ECOLI Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication. See Also |
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