3fkr

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Structure of L-2-keto-3-deoxyarabonate dehydratase complex with pyruvateStructure of L-2-keto-3-deoxyarabonate dehydratase complex with pyruvate

Structural highlights

3fkr is a 2 chain structure with sequence from Atcc 29145. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[KDADA_AZOBR] Catalyzes the dehydration of L-2-keto-3-deoxyarabonate (L-KDA) to alpha-ketoglutaric semialdehyde (alphaKGSA). Is involved in a degradation pathway of L-arabinose that allows A.brasilense to grow on L-arabinose as a sole carbon source.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Watanabe S, Shimada N, Tajima K, Kodaki T, Makino K. Identification and characterization of L-arabonate dehydratase, L-2-keto-3-deoxyarabonate dehydratase, and L-arabinolactonase involved in an alternative pathway of L-arabinose metabolism. Novel evolutionary insight into sugar metabolism. J Biol Chem. 2006 Nov 3;281(44):33521-36. Epub 2006 Sep 1. PMID:16950779 doi:http://dx.doi.org/M606727200

3fkr, resolution 1.80Å

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OCA