3fkk

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Structure of L-2-keto-3-deoxyarabonate dehydrataseStructure of L-2-keto-3-deoxyarabonate dehydratase

Structural highlights

3fkk is a 2 chain structure with sequence from Azospirillum brasilense. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KDADA_AZOBR Catalyzes the dehydration of L-2-keto-3-deoxyarabonate (L-KDA) to alpha-ketoglutaric semialdehyde (alphaKGSA). Is involved in a degradation pathway of L-arabinose that allows A.brasilense to grow on L-arabinose as a sole carbon source.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Watanabe S, Shimada N, Tajima K, Kodaki T, Makino K. Identification and characterization of L-arabonate dehydratase, L-2-keto-3-deoxyarabonate dehydratase, and L-arabinolactonase involved in an alternative pathway of L-arabinose metabolism. Novel evolutionary insight into sugar metabolism. J Biol Chem. 2006 Nov 3;281(44):33521-36. Epub 2006 Sep 1. PMID:16950779 doi:http://dx.doi.org/M606727200

3fkk, resolution 2.10Å

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OCA
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