3d6u

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Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetaseCrystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase

Structural highlights

3d6u is a 1 chain structure with sequence from Atcc 43067. This structure supersedes the now removed PDB entry 2q1g. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:tyrS, MJ0389 (ATCC 43067)
Activity:Tyrosine--tRNA ligase, with EC number 6.1.1.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Steer BA, Schimmel P. Major anticodon-binding region missing from an archaebacterial tRNA synthetase. J Biol Chem. 1999 Dec 10;274(50):35601-6. PMID:10585437

3d6u, resolution 2.20Å

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OCA
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