Sandbox29

1EVE1EVE

This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!

Created by Lori Mathis

1eve is a protein that is a drug used to prevent Alzheimer disease. The of 1EVE contains a section with 15 sheets and 16 .

1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept.  The overall protein itself was created by a Japanese corporation called the Eisai Company.

1eve, resolution 2.50Å ()

Ligands:

,

Activity:

Acetylcholinesterase, with EC number 3.1.1.7

Structural annotation:
Resources:	CATH : 1Eve000 InterPro : Ipr000908, Ipr002018, Ipr000997 Pfam : PF00135 SCOP : d1eve__ UniProt : P04058

Functional annotation:
Cellular component:	synapse cell junction membrane
Biological process:	neurotransmitter catabolic process acetylcholine catabolic process in synaptic cleft
Molecular function:	cholinesterase activity hydrolase activity GPI anchor binding acetylcholinesterase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

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