SelB

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Molecular Recognition in SelB Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms The planar base is also sandwiched between in the protein, which form a tight hydrophobic pocket. This is best seen using a The overall shape of the hairpin is recognized by contacts with several In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of

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David S. Goodsell, Eran Hodis, Eric Martz, David Canner, Michal Harel, Alexander Berchansky, Joel L. Sussman