SelB

Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms The planar base is also sandwiched between in the protein, which form a tight hydrophobic pocket. This is best seen using a The overall shape of the hairpin is recognized by contacts with several In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of This page complements the article on Selenocysteine Synthase in the Molecule of the Month Series. See also Teaching Scenes, Tutorials, and Educators' Pages.

spinqualitylabelsall models Elongation factor SelB C terminal tetramer complex with RNA 1wsu Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of SelB3D structures of SelB

1lva – MtSelB C terminal – Moorella thermoacetica
2v9v - MtSelB winged-helix domains
4aca – MmSelB – Methanococcus maripaludis

SelB complex with nucleotidesSelB complex with nucleotides

4ac9 – MmSelB + GDP
4acb – MmSelB + GPPNHP
1wsu, 2uwm - MtSelB C terminal + RNA
2pjp – EcSelB mRNA-binding domain + RNA – Eschrichia coli
2ply - EcSelB mRNA-binding domain (mutant) + RNA

Additional ResourcesAdditional Resources

For additional information, see: Translation