2co9

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Solution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouseSolution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouse

Structural highlights

2co9 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TOX_MOUSE May play a role in regulating T-cell development.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Wilkinson B, Chen JY, Han P, Rufner KM, Goularte OD, Kaye J. TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nat Immunol. 2002 Mar;3(3):272-80. Epub 2002 Feb 19. PMID:11850626 doi:http://dx.doi.org/10.1038/ni767
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