2co9

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Solution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouseSolution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouse

Structural highlights

2co9 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TOX_MOUSE May play a role in regulating T-cell development.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Wilkinson B, Chen JY, Han P, Rufner KM, Goularte OD, Kaye J. TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nat Immunol. 2002 Mar;3(3):272-80. Epub 2002 Feb 19. PMID:11850626 doi:http://dx.doi.org/10.1038/ni767
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OCA
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